Search Results - "Banerjea, Akhil C."

SARS-CoV-2 Spike Targets USP33-IRF9 Axis via Exosomal miR-148a to Activate Human Microglia by Mishra, Ritu, Banerjea, Akhil C

“…SARS-CoV-2, the novel coronavirus infection has consistently shown an association with neurological anomalies in patients, in addition to its usual respiratory…”
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Curcumin inhibits HIV-1 by promoting Tat protein degradation by Ali, Amjad, Banerjea, Akhil C.

“…HIV-1 Tat is an intrinsically unfolded protein playing a pivotal role in viral replication by associating with TAR region of viral LTR. Unfolded proteins are…”
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Neurological Damage by Coronaviruses: A Catastrophe in the Queue by Mishra, Ritu, Banerjea, Akhil C

“…Neurological disorders caused by neuroviral infections are an obvious pathogenic manifestation. However, non-neurotropic viruses or peripheral viral infections…”
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Proteasomal Degradation Machinery: Favorite Target of HIV-1 Proteins by Lata, Sneh, Mishra, Ritu, Banerjea, Akhil C

“…Proteasomal degradation pathways play a central role in regulating a variety of protein functions by controlling not only their turnover but also the…”
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Dengue Virus Dysregulates Master Transcription Factors and PI3K/AKT/mTOR Signaling Pathway in Megakaryocytes by Lahon, Anismrita, Arya, Ravi P, Banerjea, Akhil C

“…Dengue virus (DENV) infection can cause either self-limited dengue fever or hemorrhagic complications. Low platelet count is one of the manifestations of…”
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Role of RNA Interference (RNAi) in Dengue Virus Replication and Identification of NS4B as an RNAi Suppressor by Kakumani, Pavan Kumar, Ponia, Sanket Singh, S, Rajgokul K, Sood, Vikas, Chinnappan, Mahendran, Banerjea, Akhil C, Medigeshi, Guruprasad R, Malhotra, Pawan, Mukherjee, Sunil K, Bhatnagar, Raj K

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human Immunodeficiency Virus Type 1 Vif Up-Regulates the Expression of Tat via AKT Signaling Pathway: Role of Ubiquitin Specific Protease 17 by Lata, Sneh, Sood, Vikas, Banerjea, Akhil C

“…Human immunodeficiency virus type 1 (HIV-1) has RNA genome and depends on host cellular machinery for most of its activities. Host cellular proteins modulate…”
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Dengue haemorrhagic fever: a job done via exosomes? by Mishra, Ritu, Lata, Sneh, Ali, Amjad, Banerjea, Akhil C.

“…Dengue fever is one of those unique diseases where host immune responses largely determine the pathogenesis and its severity. Earlier studies have established…”
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Suppressor of Cytokine Signaling 3 (SOCS3) Degrades p65 and Regulate HIV-1 Replication by Sood, Vikas, Lata, Sneh, Ramachandran, Vishnampettai G, Banerjea, Akhil C

“…Human Immunodeficiency Virus-1 (HIV-1) is known to induce the expression of SOCS3 which is a negative feed-back regulator of inflammatory responses. Here, we…”
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The miRNA miR-34a enhances HIV-1 replication by targeting PNUTS/PPP1R10, which negatively regulates HIV-1 transcriptional complex formation by Kapoor, Richa, Arora, Sakshi, Ponia, Sanket S, Kumar, Binod, Maddika, Subbareddy, Banerjea, Akhil C

“…HIV-1 relies heavily on the host cellular machinery for its replication. During infection, HIV-1 is known to modulate the host-cell miRNA profile. One of the…”
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Molecular epidemiology of HIV-1 subtypes in India: origin and evolutionary history of the predominant subtype C by Neogi, Ujjwal, Bontell, Irene, Shet, Anita, De Costa, Ayesha, Gupta, Soham, Diwan, Vishal, Laishram, Ranbir S, Wanchu, Ajay, Ranga, Udaykumar, Banerjea, Akhil C, Sönnerborg, Anders

“…India has the third largest HIV-1 epidemic with 2.4 million infected individuals. Molecular epidemiological analysis has identified the predominance of HIV-1…”
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Dengue NS3, an RNAi suppressor, modulates the human miRNA pathways through its interacting partner by Kakumani, Pavan Kumar, Rajgokul, K S, Ponia, Sanket Singh, Kaur, Inderjeet, Mahanty, Srikrishna, Medigeshi, Guruprasad R, Banerjea, Akhil C, Chopra, Arun Prasad, Malhotra, Pawan, Mukherjee, Sunil K, Bhatnagar, Raj K

“…RNAi acts as a host immune response against non-self molecules, including viruses. Viruses evolved to neutralize this response by expressing suppressor…”
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In-Vitro Subtype-Specific Modulation of HIV-1 Trans-Activator of Transcription (Tat) on RNAi Silencing Suppressor Activity and Cell Death by Ronsard, Larance, Yousif, Ashraf S, Ramesh, Janani, Sumi, N, Gorman, Matthew, Ramachandran, Vishnampettai G, Banerjea, Akhil C

“…Human immunodeficiency virus (HIV) is a global health concern affecting millions of individuals with a wide variety of currently circulating subtypes affecting…”
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In silico Analyses of Subtype Specific HIV-1 Tat-TAR RNA Interaction Reveals the Structural Determinants for Viral Activity by Ronsard, Larance, Rai, Tripti, Rai, Devesh, Ramachandran, Vishnampettai G, Banerjea, Akhil C

“…HIV-1 Tat transactivates viral genes through strong interaction with TAR RNA. The stem-loop bulged region of TAR consisting of three nucleotides at the…”
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Molecular and genetic characterization of natural HIV-1 Tat Exon-1 variants from North India and their functional implications by Ronsard, Larance, Lata, Sneh, Singh, Jyotsna, Ramachandran, Vishnampettai G, Das, Shukla, Banerjea, Akhil C

“…Designing an ideal vaccine against HIV-1 has been difficult due to enormous genetic variability as a result of high replication rate and lack of proofreading…”
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Genetic characterization of natural variants of Vpu from HIV-1 infected individuals from Northern India and their impact on virus release and cell death by Verma, Sachin, Ronsard, Larance, Kapoor, Richa, Banerjea, Akhil C

“…Genetic studies reveal that vpu is one of the most variable regions in HIV-1 genome. Functional studies have been carried out mostly with Vpu derived from…”
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Dengue Virus Degrades USP33-ATF3 Axis via Extracellular Vesicles to Activate Human Microglial Cells by Mishra, Ritu, Lahon, Anismrita, Banerjea, Akhil C

“…Dengue virus (DENV) infection disrupts host innate immune signaling at various checkpoints. Cellular levels and stability of intermediate signaling molecules…”
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Immunogenicity and efficacy of single antigen Gp63, polytope and polytopeHSP70 DNA vaccines against visceral Leishmaniasis in experimental mouse model by Sachdeva, Rakhee, Banerjea, Akhil C, Malla, Nancy, Dubey, Mohan Lal

“…Polytope approach of genetic immunization is a promising strategy for the prevention of infectious disease as it is capable of generating effective cell…”
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Genetic and functional characterization of HIV-1 Vif on APOBEC3G degradation: First report of emergence of B/C recombinants from North India by Ronsard, Larance, Raja, Rameez, Panwar, Vaishali, Saini, Sanjesh, Mohankumar, Kumaravel, Sridharan, Subhashree, Padmapriya, Ramamoorthy, Chaudhuri, Suhnrita, Ramachandran, Vishnampettai G, Banerjea, Akhil C

“…HIV-1 is characterized by high genetic heterogeneity which is a challenge for developing therapeutics. Therefore, it is necessary to understand the extent of…”
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Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction by Ronsard, Larance, Ganguli, Nilanjana, Singh, Vivek K, Mohankumar, Kumaravel, Rai, Tripti, Sridharan, Subhashree, Pajaniradje, Sankar, Kumar, Binod, Rai, Devesh, Chaudhuri, Suhnrita, Coumar, Mohane S, Ramachandran, Vishnampettai G, Banerjea, Akhil C

“…HIV-1 evades host defense through mutations and recombination events, generating numerous variants in an infected patient. These variants with an undiminished…”
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