Search Results - "Bandres, Fernando"

Follow-up in healthy schoolchildren and in adolescents with Down syndrome: psycho-environmental and genetic determinants of physical activity and its impact on fitness, cardiovascular diseases, inflammatory biomarkers and mental health; the UP&DOWN study by Castro-Piñero, José, Carbonell-Baeza, Ana, Martinez-Gomez, David, Gómez-Martínez, Sonia, Cabanas-Sánchez, Verónica, Santiago, Catalina, Veses, Ana M, Bandrés, Fernando, Gonzalez-Galo, Ana, Gomez-Gallego, Félix, Veiga, Oscar L, Ruiz, Jonatan R, Marcos, Ascensión

“…An objective diagnosis of sedentary behaviour as well as of the physical activity and fitness levels in youth and to better understand how lifestyle is…”
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Effects of cigarette smoking and nicotine metabolite ratio on leukocyte telomere length by Verde, Zoraida, Reinoso-Barbero, Luis, Chicharro, Luis, Garatachea, Nuria, Resano, Pilar, Sánchez-Hernández, Ignacio, Rodríguez González-Moro, Jose Miguel, Bandrés, Fernando, Santiago, Catalina, Gómez-Gallego, Félix

“…Studies of the effects of smoking on leukocyte telomere length (LTL) using cigarettes smoked per day or pack years smoked (PYS) present limitations. Reported…”
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Effect of Obesity and Roux-En-Y Gastric Surgery on Omeprazole Pharmacokinetics by Portolés-Pérez, Antonio, Paterna, Ana Belén Rivas, Sánchez Pernaute, Andrés, Torres García, Antonio José, Moreno Lopera, Carmen, Chicharro, Luis M., Bandrés, Fernando, López-Picado, Amanda, Rubio, Miguel A., Castrillón, Emilio Vargas

“…Abstract Introduction: The prevalence of obesity is increasing globally. The principal aim was to evaluate whether gastric bypass surgery modifies the…”
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Physical Performance and Quality of Life in Older Adults: Is There Any Association between Them and Potential Drug Interactions in Polymedicated Octogenarians by Verde, Zoraida, García de Diego, Laura, Chicharro, Luis M, Bandrés, Fernando, Velasco, Verónica, Mingo, Teresa, Fernández-Araque, Ana

“…Older adults are at increased risk of several cytochrome P450 (CYP) drug interactions that can result in drug toxicity, reduced pharmacological effect, and…”
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Prognostic Significance of Amino Acid and Biogenic Amines Profiling in Chronic Kidney Disease by Gervasini, Guillermo, Verde, Zoraida, González, Luz M, Chicharro, Celia, González-Rodríguez, Laura, Fernández-Araque, Ana, Mota-Zamorano, Sonia, Cancho, Bárbara, Pérez-Hernández, Alberto, García-López, Virginio, Bandrés, Fernando, Robles, Nicolás R

“…There is a pressing need for more precise biomarkers of chronic kidney disease (CKD). Plasma samples from 820 subjects [231 with CKD, 325 with end-stage kidney…”
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Effect of Roux-en-Y gastric surgery on ciprofloxacin pharmacokinetics: an obvious effect? by Rivas, Ana Belén, Lopez-Picado, Amanda, Salas-Butrón, María del Rosario, Terleira, Ana, Sanchez Pernaute, Andres, Torres Garcia, Antonio José, Moreno Lopera, Carmen, Chicharro, Luis Miguel, Bandrés, Fernando, Rubio Herrera, Miguel Angel, Portolés, Antonio, Vargas, Emilio

“…Purpose To evaluate pharmacokinetic parameters of ciprofloxacin in patients undergoing Roux-en-Y gastric surgery (RYGS). Methods Controlled, single-dose,…”
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A Paradox: α-Klotho Levels and Smoking Intensity by Verde, Zoraida, González-Moro, Jose M. Rodríguez, Chicharro, Luis M., Reinoso-Barbero, Luis, Bandrés, Fernando, Gómez-Gallego, Félix, Santiago, Catalina

“…Reports regarding smoking differences in α-klotho expression have provided conflicting results. In the current study we focused on the influence of smoking…”
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A novel, single algorithm approach to predict acenocoumarol dose based on CYP2C9 and VKORC1 allele variants by Verde, Zoraida, Ruiz, Jonatan R, Santiago, Catalina, Valle, Beatriz, Bandrés, Fernando, Calvo, Elpidio, Lucía, Alejandro, Gómez Gallego, Félix

“…The identification of CYP2C9 and VKORC1 genes has strongly stimulated the research on pharmacogenetics of coumarins in the last decade. We assessed the…”
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The Effect of Polymorphisms in DNA Repair Genes and Carcinogen Metabolizers on Leukocyte Telomere Length: A Cohort of Healthy Spanish Smokers by Verde, Zoraida, Reinoso-Barbero, Luis, Chicharro, Luis, Resano, Pilar, Sánchez-Hernández, Ignacio, González-Moro, Jose Miguel Rodríguez, Bandrés, Fernando, Gómez-Gallego, Félix, Santiago, Catalina

“…Smoking implies exposure to carcinogenic agents that causes DNA damage, which could be suspected to enhance telomere attrition. To protect and deal with DNA…”
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PPARGC1A genotype (Gly482Ser) predicts exceptional endurance capacity in European men by Lucia, Alejandro, Gomez-Gallego, Felix, Barroso, Ines, Rabadan, Manuel, Bandres, Fernando, San Juan, Alejandro F, Chicharro, Jose L, Ekelund, Ulf, Brage, Soren, Earnest, Conrad P, Wareham, Nicholas J, Franks, Paul W

“…1 European University of Madrid, Madrid, Spain; 2 Department of Toxicology, Complutense University, Madrid, Spain; 3 The Wellcome Trust Sanger Institute,…”
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Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients by Romero-Lorca, Alicia, Novillo, Apolonia, Gaibar, María, Bandrés, Fernando, Fernández-Santander, Ana

“…Tamoxifen is used to prevent and treat estrogen-dependent breast cancer. It is described as a prodrug since most of its antiestrogen effects are exerted…”
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Relationship between genotypes Sult1a2 and Cyp2d6 and tamoxifen metabolism in breast cancer patients by Fernández-Santander, Ana, Gaibar, María, Novillo, Apolonia, Romero-Lorca, Alicia, Rubio, Margarita, Chicharro, Luis Miguel, Tejerina, Armando, Bandrés, Fernando

“…Tamoxifen is a pro-drug widely used in breast cancer patients to prevent tumor recurrence. Prior work has revealed a role of cytochrome and sulfotransferase…”
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CYP2D6 polymorphism screening in a selected population of Spain (La Alpujarra): No effect of geographical isolation by Fernández-Santander, Ana, Luna, Francisco, Santiago, Catalina, Rodríguez, María Teresa, Bandrés, Fernando, Ruiz, Jonatan R., Lucia, Alejandro, Gómez-Gallego, Félix

“…Background: There is growing interest in theCYP2D6 gene because of its key role in the metabolism of numerous commonly used drugs. Aim: We compared the…”
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'Smoking genes': a genetic association study by Verde, Zoraida, Santiago, Catalina, Rodríguez González-Moro, José Miguel, de Lucas Ramos, Pilar, López Martín, Soledad, Bandrés, Fernando, Lucia, Alejandro, Gómez-Gallego, Félix

“…Some controversy exists on the specific genetic variants that are associated with nicotine dependence and smoking-related phenotypes. The purpose of this study…”
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CYP2D6 polymorphism screening in a selected population of Spain (La Alpujarra): No effect of geographical isolation by Fernandez-Santander, Ana, Luna, Francisco, Santiago, Catalina, Rodriguez, Maria Teresa, Bandres, Fernando, Ruiz, Jonatan, Lucia, Alejandro, Gomez-Gallego, Felix

“…BACKGROUNDThere is growing interest in the CYP2D6 gene because of its key role in the metabolism of numerous commonly used drugs.AIMWe compared the frequency…”
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Effect of Genetic Polymorphisms and Long-Term Tobacco Exposure on the Risk of Breast Cancer by Verde, Zoraida, Santiago, Catalina, Chicharro, Luis Miguel, Reinoso-Barbero, Luis, Tejerina, Alejandro, Bandrés, Fernando, Gómez-Gallego, Félix

“…Tobacco smoke contains many potentially harmful compounds that may act differently and at different stages in breast cancer development. The focus of this work…”
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Reproductive function in male endurance athletes: sperm analysis and hormonal profile by Lucia, Alejandro, Chicharro, Jose L, Perez, Margarita, Serratosa, Luis, Bandres, Fernando, Legido., Julio C

“…Alejandro Lucía, José L. Chicharro, Margarita Pérez, Luis Serratosa, Fernando Bandrés, and Julio C. Legido. Unidad de Investigación, Facultad de Medicina,…”
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Identification of CYP2D6 null variants among long-stay, chronic psychiatric inpatients: Is it strictly necessary? by Fernández-Santander, Ana, Santiago, Catalina, Díez-Durán, Sarai, González, María, de Castro, Emilia, Guijarro, Jorge, Bandrés, Fernando, Lucia, Alejandro, Gómez-Gallego, Félix

“…We identified the null variants *3,*4,*5,*6,*7 and *8 of the CYP2D6 gene [encoding for cytochrome P450 (debrisoquine hydroxylase)] in a group of 84…”
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Are SNP-Smoking Association Studies Needed in Controls? DNA Repair Gene Polymorphisms and Smoking Intensity by Verde, Zoraida, Reinoso, Luis, Chicharro, Luis Miguel, Resano, Pilar, Sánchez-Hernández, Ignacio, Rodríguez González-Moro, Jose Miguel, Bandrés, Fernando, Gómez-Gallego, Félix, Santiago, Catalina

“…Variations in tobacco-related cancers, incidence and prevalence reflect differences in tobacco consumption in addition to genetic factors. Besides, genes…”
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Adjusting the dose of tamoxifen in patients with early breast cancer and CYP2D6 poor metabolizer phenotype by Martinez de Dueñas, Eduardo, Ochoa Aranda, Enrique, Blancas Lopez-Barajas, Isabel, Ferrer Magdalena, Teresa, Bandrés Moya, Fernando, Chicharro García, Luis Miguel, Gómez Capilla, José A, Zafra Ceres, Mercedes, de Haro, Tomás, Romero Llorens, Regina, Ferrer Albiach, Carlos, Ferriols Lisart, Rafael, Chover Lara, Dolores, López Rodríguez, Ángela, Munárriz Ferrandis, Javier, Olmos Antón, Santiago

“…Abstract Background CYP2D6 is a key enzyme in tamoxifen metabolism, transforming it into its main active metabolite, endoxifen. Poor CYP2D6 metabolizers (PM)…”
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