Search Results - "Bandini, Lorenza"

ETV6::ABL1 -Positive Myeloid Neoplasm: A Case of a Durable Response to Imatinib Mesylate without Additional or Previous Treatment by Bochicchio, Maria Teresa, Marconi, Giovanni, Baldazzi, Carmen, Bandini, Lorenza, Ruggieri, Francesca, Lucchesi, Alessandro, Agostinelli, Claudio, Sabattini, Elena, Orsatti, Agnese, Ferrari, Anna, Capirossi, Giorgia, Servili, Chiara, Ghelli Luserna di Rorà, Andrea, Martinelli, Giovanni, Simonetti, Giorgia, Rosti, Gianantonio

“…rearranged neoplasms are rare hematological diseases. To date, about 80 cases have been reported, including myeloid and lymphoid leukemias. The gene codes for…”
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Ex vivo characterization of acute myeloid leukemia patients undergoing hypomethylating agents and venetoclax regimen reveals a venetoclax-specific effect on non-suppressive regulatory T cells and bona fide PD-1 + TIM3 + exhausted CD8 + T cells by Corradi, Giulia, Forte, Dorian, Cristiano, Gianluca, Polimeno, Andrea, Ciciarello, Marilena, Salvestrini, Valentina, Bandini, Lorenza, Robustelli, Valentina, Ottaviani, Emanuela, Cavo, Michele, Ocadlikova, Darina, Curti, Antonio

“…Acute myeloid leukemia (AML) is an aggressive heterogeneous disease characterized by several alterations of the immune system prompting disease progression and…”
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Tracking Response and Resistance in Acute Myeloid Leukemia through Single-Cell DNA Sequencing Helps Uncover New Therapeutic Targets by Bruno, Samantha, Borsi, Enrica, Patuelli, Agnese, Bandini, Lorenza, Mancini, Manuela, Forte, Dorian, Nanni, Jacopo, Barone, Martina, Grassi, Alessandra, Cristiano, Gianluca, Venturi, Claudia, Robustelli, Valentina, Atzeni, Giulia, Mosca, Cristina, De Santis, Sara, Monaldi, Cecilia, Poletti, Andrea, Terragna, Carolina, Curti, Antonio, Cavo, Michele, Soverini, Simona, Ottaviani, Emanuela

“…Acute myeloid leukemia (AML) is an aggressive hematologic neoplasia with a complex polyclonal architecture. Among driver lesions, those involving the gene…”
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Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia by Bruno, Samantha, Bandini, Lorenza, Patuelli, Agnese, Robustelli, Valentina, Venturi, Claudia, Mancini, Manuela, Forte, Dorian, De Santis, Sara, Monaldi, Cecilia, Grassi, Alessandra, Chiurumbolo, Gabriella, Paolini, Stefania, Cristiano, Gianluca, Papayannidis, Cristina, Sartor, Chiara, Nanni, Jacopo, Ottaviani, Emanuela, Curti, Antonio, Cavo, Michele, Soverini, Simona

“…FMS-like tyrosine kinase 3 (FLT3) is among the most common driver genes recurrently mutated in acute myeloid leukemia (AML), accounting for approximately 30%…”
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PB1865: NPM1‐MUT MONITORING DURING GILTERITINIB TREATMENT IDENTIFIES DIFFERENT DYNAMICAL PATTERNS IN RESPONSIVE PATIENTS by Sartor, Chiara, Ottaviani, Emanuela, Nanni, Jacopo, Ciruolo, Raffaele, Cristiano, Gianluca, Zannoni, Letizia, Zingarelli, Federico, Bandini, Lorenza, Patuelli, Agnese, Venturi, Claudia, Robustellu, Valentina, Forte, Dorian, Cavo, Michele, Curti, Antonio, Papayannidis, Cristina

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The baseline comorbidity burden affects survival in elderly patients with acute myeloid leukemia receiving hypomethylating agents: Results from a multicentric clinical study by Marconi, Giovanni, Candoni, Anna, Di Nicola, Roberta, Sartor, Chiara, Parisi, Sarah, Abbenante, Mariachiara, Nanni, Jacopo, Cristiano, Gianluca, Zannoni, Letizia, Lazzarotto, Davide, Giannini, Benedetta, Baldazzi, Carmen, Bandini, Lorenza, Ottaviani, Emanuela, Testoni, Nicoletta, Bezzi, Chiara Di Giovanni, Abd‐alatif, Rania, Ciotti, Giulia, Fanin, Renato, Martinelli, Giovanni, Paolini, Stefania, Ricci, Paolo, Cavo, Michele, Papayannidis, Cristina, Curti, Antonio

“…Background In older patients with acute myeloid leukemia (AML), the definition of fitness, prognosis, and risk of death represents an open question. Methods In…”
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Iron-Related Laboratory Profile May Predict Response and MRD Negativity Rate in Acute Myeloid Leukemia Patients by Zingarelli, Federico, Cristiano, Gianluca, Sartor, Chiara, Zannoni, Letizia, Nanni, Jacopo, Barone, Martina, Bandini, Lorenza, Ottaviani, Emanuela, Robustelli, Valentina, Testoni, Nicoletta, Arpinati, Mario, Papayannidis, Cristina, Cavo, Michele, Curti, Antonio

“…Introduction: iron metabolism is deeply related to the pathogenesis and prognosis of acute myeloid leukemia (AML) and remains largely unexplored in the era of…”
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A Chemo-Free Bridge-to-Transplant Strategy with Venetoclax and Azacitidine for NPM1-Mutated Acute Myeloid Leukemia in Molecular Failure by Sartor, Chiara, Brunetti, Lorenzo, Audisio, Ernesta, Cignetti, Alessandro, Zannoni, Letizia, Cristiano, Gianluca, Nanni, Jacopo, Ottaviani, Emanuela, Bandini, Lorenza, Parisi, Sarah, Paolini, Stefania, Sciabolacci, Sofia, Cardinali, Valeria, Papayannidis, Cristina, Cavo, Michele, Martelli, Maria Paola, Curti, Antonio

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IETV6::ABL1/I-Positive Myeloid Neoplasm: A Case of a Durable Response to Imatinib Mesylate without Additional or Previous Treatment by Bochicchio, Maria Teresa, Marconi, Giovanni, Baldazzi, Carmen, Bandini, Lorenza, Ruggieri, Francesca, Lucchesi, Alessandro, Agostinelli, Claudio, Sabattini, Elena, Orsatti, Agnese, Ferrari, Anna, Capirossi, Giorgia, Servili, Chiara, Ghelli Luserna di Rorà, Andrea, Ma, Simonetti, Giorgia, Rosti, Gianantonio

“…ETV6::ABL1 rearranged neoplasms are rare hematological diseases. To date, about 80 cases have been reported, including myeloid and lymphoid leukemias. The ETV6…”
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T Cell/Natural Killer (NK) Cell Transcriptional Profiles Are Associated with Response to Gilteritinib in FLT3 -Mutated Acute Myeloid Leukemia by Nanni, Jacopo, Vadakekolathu, Jayakumar, Bandini, Lorenza, Bruno, Samantha, Zannoni, Letizia, Sartor, Chiara, Cristiano, Gianluca, Parisi, Sarah, Zingarelli, Federico, Ciruolo, Raffaele, Marconi, Giovanni, Venturi, Claudia, Ciciarello, Marilena, Kanapari, Aisi, Mazzocchetti, Gaia, Simonetti, Giorgia, Ghetti, Martina, Testoni, Nicoletta, Paolini, Stefania, Soverini, Simona, Ottaviani, Emanuela, Papayannidis, Cristina, Cavo, Michele, Rutella, Sergio, Curti, Antonio

“…S.R. & A.C. equally contributed Background: Despite significative improvements in the management of FLT3-mutated AML and its prognosis since FLT3 inhibitors (…”
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An Outpatient Management for First Cycle of Venetoclax and Hypomethylating Agents Results in Reduced Infection Rate and Hospitalizations in Acute Myeloid Leukemia Patients by Nanni, Jacopo, Papayannidis, Cristina, Cristiano, Gianluca, Marconi, Giovanni, Sartor, Chiara, Parisi, Sarah, Saed, Rashed, Zannoni, Letizia, Ottaviani, Emanuela, Bandini, Lorenza, Testoni, Nicoletta, Baldazzi, Carmen, Ricci, Paolo, Di Giovanni Bezzi, Chiara, Abd-alatif, Rania, Paolini, Stefania, Cavo, Michele, Curti, Antonio

“…Introduction In the setting of clinical trials Venetoclax (VEN) combined with hypomethylating agents (HMAs) has shown fair activity in Relapsed/Refractory…”
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IDH1/2 Mutations Are Maintained in a Subset of Patients with Acute Myeloid Leukemia in Complete Remission and Do Not Correlate with Residual Disease by Marconi, Giovanni, Bandini, Lorenza, Patuelli, Agnese, Sartor, Chiara, Parisi, Sarah, Nanni, Jacopo, Cristiano, Gianluca, Zannoni, Letizia, Simonetti, Giorgia, Bochicchio, Maria Teresa, Ottaviani, Emanuela, Martinelli, Giovanni, Paolini, Stefania, Papayannidis, Cristina, Cavo, Michele, Curti, Antonio

“…Rationale: Isocitrate dehydrogenase 1 and 2 (IDH1/2) mutations may be the nearest signal to in vivo leukemogenesis that we are able to see in overt acute…”
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Release of IFN-γ by acute myeloid leukemia cells remodels bone marrow immune microenvironment by inducing regulatory T cells by Corradi, Giulia, Bassani, Barbara, Simonetti, Giorgia, Sangaletti, Sabina, Vadakekolathu, Jayakumar, Fontana, Maria Chiara, Pazzaglia, Martina, Gulino, Alessandro, Tripodo, Claudio, Cristiano, Gianluca, Bandini, Lorenza, Ottaviani, Emanuela, Ocadlikova, Darina, Piccioli, Milena, Martinelli, Giovanni, Colombo, Mario Paolo, Rutella, Sergio, Cavo, Michele, Ciciarello, Marilena, Curti, Antonio

“…The stromal and immune bone marrow (BM) landscape is emerging as a crucial determinant for acute myeloid leukemia (AML). Regulatory T cells (Tregs) are…”
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Impact of Comorbidities on Prognosis of Elderly Patients with Acute Myeloid Leukemia Who Receive Hypomethylating Agents by Marconi, Giovanni, Candoni, Anna, di Nicola, Roberta, Sartor, Chiara, Parisi, Sarah, Abbenante, Mariachiara, Nanni, Jacopo, Cristiano, Gianluca, Lazzarotto, Davide, Giannini, Maria Benedetta, Baldazzi, Carmen, Fontana, Maria Chiara, Bandini, Lorenza, Ottaviani, Emanuela, Testoni, Nicoletta, Di Giovanni Bezzi, Chiara, Abd-alatif, Rania, Fanin, Renato, Martinelli, Giovanni, Paolini, Stefania, Cavo, Michele, Papayannidis, Cristina, Curti, Antonio

“…BACKGROUND: Many efforts have been made in the attempt to address the conundrum question of fitness definition ad prognosis prediction in elderly acute myeloid…”
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Impact of infectious comorbidity and overall time of hospitalization in total outpatient management of acute myeloid leukemia patients following venetoclax and hypomethylating agents by Papayannidis, Cristina, Nanni, Jacopo, Cristiano, Gianluca, Marconi, Giovanni, Sartor, Chiara, Parisi, Sarah, Zannoni, Letizia, Saed, Rashed, Ottaviani, Emanuela, Bandini, Lorenza, Testoni, Nicoletta, Baldazzi, Carmen, Solli, Vincenza, Ricci, Paolo, Di Giovanni Bezzi, Chiara, Abd‐alatif, Rania, Stanzani, Marta, Paolini, Stefania, Cavo, Michele, Curti, Antonio

“…Venetoclax (VEN) and hypomethylating agent (HMAs) regimens are emerging as the standard of care for unfit for chemotherapy acute myeloid leukemia (AML)…”
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AML-CM Score Predicts Prognosis in Hemato-Geriatric Patients with New-Onset Acute Myeloid Leukemia (AML) Who Receive Hypomethylating Agents (HMA) by Marconi, Giovanni, di Nicola, Roberta, Sartor, Chiara, Abbenante, Mariachiara, Nanni, Jacopo, Cristiano, Gianluca, Parisi, Sarah, Baldazzi, Carmen, Fontana, Maria Chiara, Bandini, Lorenza, Ottaviani, Emanuela, Testoni, Nicoletta, Martinelli, Giovanni, Baccarani, Michele, Papayannidis, Cristina, Paolini, Stefania, Cavo, Michele, Curti, Antonio

“…Background Although much efforts have been made to precisely define fitness of AML patients, in patients who are not candidate to chemotherapy, there is no…”
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Identification of Two DNMT3A Mutations Compromising Protein Stability and Methylation Capacity in Acute Myeloid Leukemia by Bruno, Samantha, Bochicchio, Maria Teresa, Franchini, Eugenia, Padella, Antonella, Marconi, Giovanni, Ghelli Luserna di Rorà, Andrea, Venturi, Claudia, Raffini, Maddalena, Prisinzano, Giovanna, Ferrari, Anna, Bandini, Lorenza, Robustelli, Valentina, Pazzaglia, Martina, Fontana, Maria Chiara, Sartor, Chiara, Abbenante, Maria Chiara, Papayannidis, Cristina, Soverini, Simona, Ottaviani, Emanuela, Simonetti, Giorgia, Martinelli, Giovanni

“…Somatic mutations of DNMT3A occur in about 20% of acute myeloid leukemia (AML) patients. They mostly consist in heterozygous missense mutations targeting a…”
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ETV6::ABL1-Positive Myeloid Neoplasm: A Case of a Durable Response to Imatinib Mesylate without Additional or Previous Treatment by Bochicchio, Maria Teresa, Marconi, Giovanni, Baldazzi, Carmen, Bandini, Lorenza, Ruggieri, Francesca, Lucchesi, Alessandro, Agostinelli, Claudio, Sabattini, Elena, Orsatti, Agnese, Ferrari, Anna, Capirossi, Giorgia, Servili, Chiara, Ghelli Luserna di Rorà, Andrea, Martinelli, Giovanni, Simonetti, Giorgia, Rosti, Gianantonio

“…ETV6::ABL1 rearranged neoplasms are rare hematological diseases. To date, about 80 cases have been reported, including myeloid and lymphoid leukemias. The ETV6…”
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Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia by Bruno, Samantha, Bandini, Lorenza, Patuelli, Agnese, Robustelli, Valentina, Venturi, Claudia, Mancini, Manuela, te, Dorian, De Santis, Sara, Monaldi, Cecilia, Grassi, Alessandra, Chiurumbolo, Gabriella, Paolini, Stefania, Cristiano, Gianluca, Papayannidis, Cristina, Sartor, Chiara, Nanni, Jacopo, Ottaviani, Emanuela, Curti, Antonio, Cavo, Michele, Soverini, Simona

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