Search Results - "Bandeira‐Melo, Christianne"

Uvaol attenuates pleuritis and eosinophilic inflammation in ovalbumin-induced allergy in mice by Agra, Lais Costa, Lins, Marvin Paulo, da Silva Marques, Patrícia, Smaniotto, Salete, Bandeira de Melo, Christianne, Lagente, Vincent, Barreto, Emiliano

“…Uvaol, a triterpene present in olives and virgin olive oil, has been shown to possess anti-inflammatory properties and antioxidant effects. However, until now,…”
Get full text

Lipid body function in eicosanoid synthesis: An update by Bozza, Patricia T, Bakker-Abreu, Ilka, Navarro-Xavier, Roberta A, Bandeira-Melo, Christianne

“…Abstract Eicosanoids (prostaglandins, leukotrienes and lipoxins) are signaling lipids derived from arachidonic acid metabolism that have important roles in…”
Get full text

Parasitic infections: A new frontier for PGD2 functions by Diaz, Bruno L., Bandeira-Melo, Christianne

“…Prostaglandin (PG)D2 is produced and/or triggered by different parasites to modulate the course of the infection. These findings position PGD2 as a therapeutic…”
Get full text

Endogenous PGD2 acting on DP2 receptor counter regulates Schistosoma mansoni infection-driven hepatic granulomatous fibrosis by Pezzella-Ferreira, Giovanna N, Pão, Camila R R, Bellas, Isaac, Luna-Gomes, Tatiana, Muniz, Valdirene S, Paiva, Ligia A, Amorim, Natalia R T, Canetti, Claudio, Bozza, Patricia T, Diaz, Bruno L, Bandeira-Melo, Christianne

“…Identifying new molecular therapies targeted at the severe hepatic fibrosis associated with the granulomatous immune response to Schistosoma mansoni infection…”
Get full text

Inflammatory profiling of patients with familial amyloid polyneuropathy by Azevedo, Estefania P, Guimaraes-Costa, Anderson B, Bandeira-Melo, Christianne, Chimelli, Leila, Waddington-Cruz, Marcia, Saraiva, Elvira M, Palhano, Fernando L, Foguel, Debora

“…Familial amyloid polyneuropathy (FAP) or ATTRv (amyloid TTR variant) amyloidosis is a fatal hereditary disease characterized by the deposition of amyloid…”
Get full text

Leptin Mediates In Vivo Neutrophil Migration: Involvement of Tumor Necrosis Factor-Alpha and CXCL1 by Souza-Almeida, Glaucia, D'Avila, Heloisa, Almeida, Patricia E, Luna-Gomes, Tatiana, Liechocki, Sally, Walzog, Barbara, Hepper, Ingrid, Castro-Faria-Neto, Hugo Caire, Bozza, Patricia T, Bandeira-Melo, Christianne, Maya-Monteiro, Clarissa M

“…Leptin directly activates macrophages and lymphocytes, but the role of leptin in neutrophil activation and migration is still controversial. Here, we…”
Get full text

Prostaglandins regulate humoral immune responses in Aedes aegypti by Barletta, Ana Beatriz Ferreira, Alves E Silva, Thiago Luiz, Talyuli, Octavio A C, Luna-Gomes, Tatiana, Sim, Shuzhen, Angleró-Rodríguez, Yesseinia, Dimopoulos, George, Bandeira-Melo, Christianne, Sorgine, Marcos H Ferreira

“…Prostaglandins (PGs) are immuno-active lipids that mediate the immune response in invertebrates and vertebrates. In insects, PGs play a role on different…”
Get full text

Leptin Elicits In Vivo Eosinophil Migration and Activation: Key Role of Mast Cell-Derived PGD2 by Amorim, Natália R. T., Souza-Almeida, Glaucia, Luna-Gomes, Tatiana, Bozza, Patricia T., Canetti, Claudio, Diaz, Bruno L., Maya-Monteiro, Clarissa M., Bandeira-Melo, Christianne

“…Eosinophils are key regulators of adipose tissue homeostasis, thus characterization of adipose tissue-related molecular factors capable of regulating…”
Get full text

The PGE2/IL-10 Axis Determines Susceptibility of B-1 Cell-Derived Phagocytes (B-1CDP) to Leishmania major Infection by Arcanjo, Angélica F, LaRocque-de-Freitas, Isabel F, Rocha, Juliana Dutra B, Zamith, Daniel, Costa-da-Silva, Ana Caroline, Nunes, Marise Pinheiro, Mesquita-Santos, Fabio P, Morrot, Alexandre, Filardy, Alessandra A, Mariano, Mario, Bandeira-Melo, Christianne, DosReis, George A, Decote-Ricardo, Debora, Freire-de-Lima, Célio Geraldo

“…B-1 cells can be differentiated from B-2 cells because they are predominantly located in the peritoneal and pleural cavities and have distinct phenotypic…”
Get full text

Leptin Elicits LTC4 Synthesis by Eosinophils Mediated by Sequential Two-Step Autocrine Activation of CCR3 and PGD2 Receptors by Amorim, Natália R. T., Luna-Gomes, Tatiana, Gama-Almeida, Marcos, Souza-Almeida, Glaucia, Canetti, Claudio, Diaz, Bruno L., Weller, Peter F., Torres Bozza, Patricia, Maya-Monteiro, Clarissa M., Bandeira-Melo, Christianne

“…Leptin is a cytokine, produced mainly by mature adipocytes, that regulates the central nervous system, mainly to suppress appetite and stimulate energy…”
Get full text

Purinergic P2Y12 Receptor Activation in Eosinophils and the Schistosomal Host Response by Muniz, Valdirene S, Baptista-Dos-Reis, Renata, Benjamim, Claudia F, Mata-Santos, Hilton A, Pyrrho, Alexandre S, Strauch, Marcelo A, Melo, Paulo A, Vicentino, Amanda R R, Silva-Paiva, Juliana, Bandeira-Melo, Christianne, Weller, Peter F, Figueiredo, Rodrigo T, Neves, Josiane S

“…Identifying new target molecules through which eosinophils secrete their stored proteins may reveal new therapeutic approaches for the control of eosinophilic…”
Get full text

Leukotriene B4 mediates neutrophil migration induced by heme by Monteiro, Ana Paula T, Pinheiro, Carla S, Luna-Gomes, Tatiana, Alves, Liliane R, Maya-Monteiro, Clarissa M, Porto, Barbara N, Barja-Fidalgo, Christina, Benjamim, Claudia F, Peters-Golden, Marc, Bandeira-Melo, Christianne, Bozza, Marcelo T, Canetti, Claudio

“…High concentrations of free heme found during hemolytic events or cell damage leads to inflammation, characterized by neutrophil recruitment and production of…”
Get full text

Mitochondrial Population in Mouse Eosinophils: Ultrastructural Dynamics in Cell Differentiation and Inflammatory Diseases by Bonjour, Kennedy, Palazzi, Cinthia, Silva, Thiago P, Malta, Kássia K, Neves, Vitor H, Oliveira-Barros, Eliane G, Neves, Igor, Kersten, Victor A, Fortuna, Bruno T, Samarasinghe, Amali E, Weller, Peter F, Bandeira-Melo, Christianne, Melo, Rossana C N

“…Mitochondria are multifunctional organelles of which ultrastructure is tightly linked to cell physiology. Accumulating evidence shows that mitochondrial…”
Get full text

Schistosomal Lipids Activate Human Eosinophils via Toll-Like Receptor 2 and PGD2 Receptors: 15-LO Role in Cytokine Secretion by Magalhães, Kelly G., Luna-Gomes, Tatiana, Mesquita-Santos, Fabio, Corrêa, Rafael, Assunção, Leonardo Santos, Atella, Georgia Correa, Weller, Peter F., Bandeira-Melo, Christianne, Bozza, Patricia T.

“…Parasite-derived lipids may play important roles in host-pathogen interactions and immune evasion mechanisms. Remarkable accumulation of eosinophils is a…”
Get full text

Eosinophil recruitment and activation: the role of lipid mediators by Luna-Gomes, Tatiana, Bozza, Patrícia T, Bandeira-Melo, Christianne

“…Eosinophils are effector cells that migrate toward several mediators released at inflammatory sites to perform their multiple functions. The mechanisms driving…”
Get full text

Monocyte Chemoattractant Protein-1/CC Chemokine Ligand 2 Controls Microtubule-Driven Biogenesis and Leukotriene B4-Synthesizing Function of Macrophage Lipid Bodies Elicited by Innate Immune Response by Pacheco, Patricia, Vieira-de-Abreu, Adriana, Gomes, Rachel N, Barbosa-Lima, Giselle, Wermelinger, Leticia B, Maya-Monteiro, Clarissa M, Silva, Adriana R, Bozza, Marcelo T, Castro-Faria-Neto, Hugo C, Bandeira-Melo, Christianne, Bozza, Patricia T

“…Lipid bodies (also known as lipid droplets) are emerging as inflammatory organelles with roles in the innate immune response to infections and inflammatory…”
Get full text

EicosaCell - an immunofluorescent-based assay to localize newly synthesized eicosanoid lipid mediators at intracellular sites by Bandeira-Melo, Christianne, Weller, Peter F, Bozza, Patricia T

“…Eicosanoids (prostaglandins, leukotrienes and lipoxins) are a family of signaling lipids derived from arachidonic acid that have important roles in…”
Get more information

Extranuclear Lipid Bodies, Elicited by CCR3-mediated Signaling Pathways, Are the Sites of Chemokine-enhanced Leukotriene C4 Production in Eosinophils and Basophils by Bandeira-Melo, Christianne, Phoofolo, Mojabeng, Weller, Peter F.

“…Eosinophils and basophils, when activated, become major sources of cysteinyl leukotrienes, eicosanoid mediators pertinent to allergic inflammation. We show…”
Get full text

Anti-inflammatory Activity in the Aqueous Crude Extract of the Leaves of Nidularium procerum: A Bromeliaceae from the Brazilian Coastal Rain Forest by Amendoeira, Fabio Coelho, Frutuoso, Valber Silva, Zanon, Cristiane, Chedier, Luciana Moreira, Figueiredo, Maria Raquel, Kaplan, Maria Auxiliadora Coelho, Bandeira-Melo, Christianne, Bozza, Patrícia Torres, Castro-Faria-Neto, Hugo Caire

“…Nidularium procerum LINDMAN, a common bromeliaceae from the Brazilian flora, remains poorly studied regarding its chemical and pharmacological properties. We…”
Get full text

Hepatic myofibroblasts derived from Schistosoma mansoni-infected mice are a source of IL-5 and eotaxin: controls of eosinophil populations in vitro by Paiva, Ligia Almeida, Brand, Camila, Bandeira-Melo, Christianne, Bozza, Patricia Torres, El-Cheikh, Marcia Cury, Silva, Patricia Martins, Borojevic, Radovan, Perez, Sandra Aurora Chavez

“…Hepatic myofibroblasts are relevant for pathogenesis of S. mansoni infection. In normal liver, these perisinusoidal cells are quiescent, express the lipocyte…”
Get full text