Search Results - "Bandara, Y M Nuwan D Y"
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Surveying silicon nitride nanopores for glycomics and heparin quality assurance
Published in Nature communications (16-08-2018)“…Polysaccharides have key biological functions and can be harnessed for therapeutic roles, such as the anticoagulant heparin. Their complexity—e.g., >100…”
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2
Adeno-associated virus characterization for cargo discrimination through nanopore responsiveness
Published in Nanoscale (08-12-2020)“…Solid-state nanopore (SSN)-based analytical methods have found abundant use in genomics and proteomics with fledgling contributions to virology - a clinically…”
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Nanopore Current Enhancements Lack Protein Charge Dependence and Elucidate Maximum Unfolding at Protein’s Isoelectric Point
Published in Journal of the American Chemical Society (23-02-2022)“…Protein sequencing, as well as protein fingerprinting, has gained tremendous attention in the electrical sensing realm of solid-state nanopores and is…”
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On the origins of conductive pulse sensing inside a nanopore
Published in Nature communications (13-05-2022)“…Nanopore sensing is nearly synonymous with resistive pulse sensing due to the characteristic occlusion of ions during pore occupancy, particularly at high salt…”
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5
Modulation of electrophoresis, electroosmosis and diffusion for electrical transport of proteins through a solid-state nanopore
Published in RSC advances (12-07-2021)“…Nanopore probing of molecular level transport of proteins is strongly influenced by electrolyte type, concentration, and solution pH. As a result, electrolyte…”
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6
Chemically Functionalizing Controlled Dielectric Breakdown Silicon Nitride Nanopores by Direct Photohydrosilylation
Published in ACS applied materials & interfaces (21-08-2019)“…Nanopores are a prominent enabling tool for single-molecule applications such as DNA sequencing, protein profiling, and glycomics, and the construction of…”
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Investigating protein translocation in the presence of an electrolyte concentration gradient across a solid‐state nanopore
Published in Electrophoresis (01-03-2022)“…Electrolyte chemistry plays an important role in the transport properties of analytes through nanopores. Here, we report the translocation properties of the…”
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Stiffness measurement of nanosized liposomes using solid‐state nanopore sensor with automated recapturing platform
Published in Electrophoresis (01-05-2019)“…This paper describes a method to gauge the stiffness of nanosized liposomes – a nanoscale vesicle – using a custom‐made recapture platform coupled to a…”
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Fabrication of hexagonal boron nitride based 2D nanopore sensor for the assessment of electro‐chemical responsiveness of human serum transferrin protein
Published in Electrophoresis (01-04-2020)“…In this work, we present a step‐by‐step workflow for the fabrication of 2D hexagonal boron nitride (h‐BN) nanopores which are then used to sense holo‐human…”
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10
Real-Time Profiling of Solid-State Nanopores During Solution-Phase Nanofabrication
Published in ACS applied materials & interfaces (09-11-2016)“…We describe a method for simply characterizing the size and shape of a nanopore during solution-based fabrication and surface modification, using only…”
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Assessment of 1/f noise associated with nanopores fabricated through chemically tuned controlled dielectric breakdown
Published in Electrophoresis (01-04-2021)“…Recently, we developed a fabrication method—chemically‐tuned controlled dielectric breakdown (CT‐CDB)—that produces nanopores (through thin silicon nitride…”
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12
Push-Button Method To Create Nanopores Using a Tesla-Coil Lighter
Published in ACS omega (31-01-2019)“…Controlled dielectric breakdown (CDB) of silicon nitride thin films immersed in electrolyte solution has been used to fabricate single nanofluidic channels…”
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13
Mechanical characterization of vesicles and cells: A review
Published in Electrophoresis (01-04-2020)“…Vesicles perform many essential functions in all living organisms. They respond like a transducer to mechanical stress in converting the applied force into…”
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Synthetic β‐Cyclodextrin Dimers for Squaraine Binding: Effect of Host Architecture on Photophysical Properties, Aggregate Formation and Chemical Reactivity
Published in European journal of organic chemistry (08-05-2018)“…Reported herein is the synthesis and application of three novel β‐cyclodextrin dimer hosts for the complexation of near infrared (NIR) squaraine dyes in…”
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Surface Functionalization and Texturing of Optical Metasurfaces for Sensing Applications
Published in Chemical reviews (12-10-2022)“…Optical metasurfaces are planar metamaterials that can mediate highly precise light–matter interactions. Because of their unique optical properties, both…”
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Nanopore Data Analysis: Baseline Construction and Abrupt Change-Based Multilevel Fitting
Published in Analytical chemistry (Washington) (31-08-2021)“…Solid-state nanopore technology delivers single-molecule resolution information, and the quality of the deliverables hinges on the capability of the analysis…”
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Molecular-Level Profiling of Human Serum Transferrin Protein through Assessment of Nanopore-Based Electrical and Chemical Responsiveness
Published in ACS nano (23-04-2019)“…In this study, we investigated the voltage and pH responsiveness of human serum transferrin (hSTf) protein using silicon nitride (Si x N y ) nanopores. The…”
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Characterization of Flagellar Filaments and Flagellin through Optical Microscopy and Label-Free Nanopore Responsiveness
Published in Analytical chemistry (Washington) (05-11-2019)“…In this study, we investigated the translocation characteristics of flagellar filaments (Salmonella typhimurium) and flagellin subunits through silicon nitride…”
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Solution-Based Photo-Patterned Gold Film Formation on Silicon Nitride
Published in ACS applied materials & interfaces (28-12-2016)“…Silicon nitride fabricated by low-pressure chemical vapor deposition (LPCVD) to be silicon-rich (SiN x ), is a ubiquitous insulating thin film in the…”
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Chemically tailoring nanopores for single-molecule sensing and glycomics
Published in Analytical and bioanalytical chemistry (01-10-2020)“…A nanopore can be fairly—but uncharitably—described as simply a nanofluidic channel through a thin membrane. Even this simple structural description holds…”
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