Search Results - "Banck, Michaela S."

The genomic landscape of small intestine neuroendocrine tumors by Banck, Michaela S, Kanwar, Rahul, Kulkarni, Amit A, Boora, Ganesh K, Metge, Franziska, Kipp, Benjamin R, Zhang, Lizhi, Thorland, Erik C, Minn, Kay T, Tentu, Ramesh, Eckloff, Bruce W, Wieben, Eric D, Wu, Yanhong, Cunningham, Julie M, Nagorney, David M, Gilbert, Judith A, Ames, Matthew M, Beutler, Andreas S

“…Small intestine neuroendocrine tumors (SI-NETs) are the most common malignancy of the small bowel. Several clinical trials target PI3K/Akt/mTOR signaling;…”
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Patient-reported (EORTC QLQ-CIPN20) versus physician-reported (CTCAE) quantification of oxaliplatin- and paclitaxel/carboplatin-induced peripheral neuropathy in NCCTG/Alliance clinical trials by Le-Rademacher, Jennifer, Kanwar, Rahul, Seisler, Drew, Pachman, Deirdre R., Qin, Rui, Abyzov, Alexej, Ruddy, Kathryn J., Banck, Michaela S., Lavoie Smith, Ellen M., Dorsey, Susan G., Aaronson, Neil K., Sloan, Jeff, Loprinzi, Charles L., Beutler, Andreas S.

“…Purpose Clinical practice guidelines on chemotherapy-induced peripheral neuropathy (CIPN) use the NCI Common Terminology Criteria for Adverse Events (CTCAE),…”
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Biomarkers of Resistance to Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients with Metastatic Colorectal Cancer by BANCK, Michaela S, GROTHEY, Axel

“…Genomics and proteomics have held out the promise of individualized medicine for the last 10 or 20 years, but clinical medicine has not yet delivered on this…”
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Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain by Storek, Benjamin, Reinhardt, Matthias, Wang, Cheng, Janssen, William G.M, Harder, Nina M, Banck, Michaela S, Morrison, John H, Beutler, Andreas S

“…Lumbar puncture (LP) is an attractive route to deliver drugs to the nervous system because it is a safe bedside procedure. Its use for gene therapy has been…”
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The ZNF217 oncogene is a candidate organizer of repressive histone modifiers by Banck, Michaela S, Li, Side, Nishio, Hitomi, Wang, Cheng, Beutler, Andreas S, Walsh, Martin J

“…The zinc finger protein 217 (ZNF217) is an important oncogene based on the high frequency of amplification and over-expression in many cancer types, but its…”
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Diametrically opposite methylome-transcriptome relationships in high- and low-CpG promoter genes in postmitotic neural rat tissue by Hartung, Theresa, Zhang, Lu, Kanwar, Rahul, Khrebtukova, Irina, Reinhardt, Matthias, Wang, Cheng, Therneau, Terry M, Banck, Michaela S, Schroth, Gary P, Beutler, Andreas S

“…DNA methylation can control some CpG-poor genes but unbiased studies have not found a consistent genome-wide association with gene activity outside of CpG…”
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Somatic mutation of CDKN1B in small intestine neuroendocrine tumors by Francis, Joshua M, Kiezun, Adam, Ramos, Alex H, Serra, Stefano, Pedamallu, Chandra Sekhar, Qian, Zhi Rong, Banck, Michaela S, Kanwar, Rahul, Kulkarni, Amit A, Karpathakis, Anna, Manzo, Veronica, Contractor, Tanupriya, Philips, Juliet, Nickerson, Elizabeth, Pho, Nam, Hooshmand, Susanne M, Brais, Lauren K, Lawrence, Michael S, Pugh, Trevor, McKenna, Aaron, Sivachenko, Andrey, Cibulskis, Kristian, Carter, Scott L, Ojesina, Akinyemi I, Freeman, Samuel, Jones, Robert T, Voet, Douglas, Saksena, Gordon, Auclair, Daniel, Onofrio, Robert, Shefler, Erica, Sougnez, Carrie, Grimsby, Jonna, Green, Lisa, Lennon, Niall, Meyer, Tim, Caplin, Martyn, Chung, Daniel C, Beutler, Andreas S, Ogino, Shuji, Thirlwell, Christina, Shivdasani, Ramesh, Asa, Sylvia L, Harris, Chris R, Getz, Gad, Kulke, Matthew, Meyerson, Matthew

“…Matthew Meyerson and colleagues report whole-exome and whole-genome sequencing of 55 small intestine neuroendocrine tumors. They identify recurrent somatic…”
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KLF6 degradation after apoptotic DNA damage by Banck, Michaela S., Beaven, Simon W., Narla, Goutham, Walsh, Martin J., Friedman, Scott L., Beutler, Andreas S.

“…Krüppel-like factor 6 (KLF6) is a cancer gene (www.sanger.ac.uk/genetics/CGP/Census/). Here, we demonstrate that KLF6 protein is rapidly degraded when…”
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Response to “Unilateral Periganglionic Resiniferatoxin (RTX) for Personalized Pain Treatment” by Beutler, Andreas S, Unger, Mark D, Banck, Michaela S, Maus, Timothy P

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Sequencing of Charcot-Marie-Tooth disease genes in a toxic polyneuropathy by Beutler, Andreas S., Kulkarni, Amit A., Kanwar, Rahul, Klein, Christopher J., Therneau, Terry M., Qin, Rui, Banck, Michaela S., Boora, Ganesh K., Ruddy, Kathryn J., Wu, Yanhong, Smalley, Regenia L., Cunningham, Julie M., Le-Lindqwister, Nguyet Anh, Beyerlein, Peter, Schroth, Gary P., Windebank, Anthony J., Züchner, Stephan, Loprinzi, Charles L.

“…Objective Mutations in Charcot–Marie–Tooth disease (CMT) genes are the cause of rare familial forms of polyneuropathy. Whether allelic variability in CMT genes…”
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Association of the Charcot–Marie–Tooth disease gene ARHGEF10 with paclitaxel induced peripheral neuropathy in NCCTG N08CA (Alliance) by Boora, Ganesh K, Kulkarni, Amit A, Kanwar, Rahul, Beyerlein, Peter, Qin, Rui, Banck, Michaela S, Ruddy, Kathryn J, Pleticha, Josef, Lynch, Cynthia A, Behrens, Robert J, Züchner, Stephan, Loprinzi, Charles L, Beutler, Andreas S

“…Abstract The predisposition of patients to develop polyneuropathy in response to toxic exposure may have a genetic basis. The previous study Alliance N08C1…”
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Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines by Boora, Ganesh K, Kanwar, Rahul, Kulkarni, Amit A, Pleticha, Josef, Ames, Matthew, Schroth, Gary, Beutler, Andreas S, Banck, Michaela S

“…Neuroendocrine cancer cell lines are used to investigate therapeutic targets in neuroendocrine tumors (NET) and have been instrumental in the design of…”
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Neurological safety of oxaliplatin in patients with uncommon variants in Charcot-Marie-tooth disease genes by Le-Rademacher, Jennifer G., Lopez, Camden L., Kanwar, Rahul, Major-Elechi, Brittny, Abyzov, Alexej, Banck, Michaela S., Therneau, Terry M., Sloan, Jeff A., Loprinzi, Charles L., Beutler, Andreas S.

“…Oxaliplatin therapy can be complicated by chemotherapy-induced peripheral neuropathy (CIPN). Other neurotoxic chemotherapies have been linked to single…”
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mRNA-seq with agnostic splice site discovery for nervous system transcriptomics tested in chronic pain by Hammer, Paul, Banck, Michaela S, Amberg, Ronny, Wang, Cheng, Petznick, Gabriele, Luo, Shujun, Khrebtukova, Irina, Schroth, Gary P, Beyerlein, Peter, Beutler, Andreas S

“…mRNA-seq is a paradigm-shifting technology because of its superior sensitivity and dynamic range and its potential to capture transcriptomes in an agnostic…”
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Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery by Bryce, Alan H, Egan, Jan B, Borad, Mitesh J, Stewart, A Keith, Nowakowski, Grzegorz S, Chanan-Khan, Asher, Patnaik, Mrinal M, Ansell, Stephen M, Banck, Michaela S, Robinson, Steven I, Mansfield, Aaron S, Klee, Eric W, Oliver, Gavin R, McCormick, Jennifer B, Huneke, Norine E, Tagtow, Colleen M, Jenkins, Robert B, Rumilla, Kandelaria M, Kerr, Sarah E, Kocher, Jean-Pierre A, Beck, Scott A, Fernandez-Zapico, Martin E, Farrugia, Gianrico, Lazaridis, Konstantinos N, McWilliams, Robert R

“…The ability to analyze the genomics of malignancies has opened up new possibilities for off-label targeted therapy in cancers that are refractory to standard…”
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Unilateral Epidural Targeting of Resiniferatoxin Induces Bilateral Neurolysis of Spinal Nociceptive Afferents by Unger, Mark D, Pleticha, Josef, Steinauer, Joanne, Kanwar, Rahul, Diehn, Felix, LaVallee, Katherine T, Banck, Michaela S, Jones, Bryan, Yaksh, Tony L, Maus, Timothy P, Beutler, Andreas S

“…Abstract Objective This study modeled image-guided epidural drug delivery to test whether intraprocedural distribution of pre-injected contrast reliably…”
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Advances in small bowel neuroendocrine neoplasia by Banck, Michaela S, Beutler, Andreas S

“…PURPOSE OF REVIEWThis review aims at summarizing progress in clinical trials and basic science redefining the diagnosis and treatment of well differentiated…”
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Testing of candidate single nucleotide variants associated with paclitaxel neuropathy in the trial NCCTG N08C1 (Alliance) by Boora, Ganesh K., Kanwar, Rahul, Kulkarni, Amit A., Abyzov, Alexej, Sloan, Jeff, Ruddy, Kathryn J., Banck, Michaela S., Loprinzi, Charles L., Beutler, Andreas S.

“…Paclitaxel‐induced peripheral neuropathy (PIPN) cannot be predicted from clinical parameters and might have a pharmacogenomic basis. Previous studies…”
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Plasticity of DNA methylation in a nerve injury model of pain by Gölzenleuchter, Meike, Kanwar, Rahul, Zaibak, Manal, Al Saiegh, Fadi, Hartung, Theresa, Klukas, Jana, Smalley, Regenia L, Cunningham, Julie M, Figueroa, Maria E, Schroth, Gary P, Therneau, Terry M, Banck, Michaela S, Beutler, Andreas S

“…The response of the peripheral nervous system (PNS) to injury may go together with alterations in epigenetics, a conjecture that has not been subjected to a…”
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RWDD3 and TECTA variants not linked to paclitaxel induced peripheral neuropathy in North American trial Alliance N08C1 by Kulkarni, Amit A, Boora, Ganesh, Kanwar, Rahul, Ruddy, Kathryn J, Banck, Michaela S, Le-Lindqwister, Nguyet, Therneau, Terry M, Loprinzi, Charles L, Beutler, Andreas S

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