Search Results - "Banack, S. A."

Cyanobacterial neurotoxin BMAA in ALS and Alzheimer's disease by Pablo, J., Banack, S. A., Cox, P. A., Johnson, T. E., Papapetropoulos, S., Bradley, W. G., Buck, A., Mash, D. C.

“…Objective –  The aim of this study was to screen for and quantify the neurotoxic amino acid β‐N‐methylamino‐l‐alanine (BMAA) in a cohort of autopsy specimens…”
Get full text

Nitrogen starvation of cyanobacteria results in the production of β-N-methylamino-L-alanine by Downing, S., Banack, S.A., Metcalf, J.S., Cox, P.A., Downing, T.G.

“…β-N-methylamino-L-alanine, an unusual amino acid implicated in neurodegenerative disease, has been detected in cultures of nearly all genera of environmentally…”
Get full text

Occurrence of β-methylamino-l-alanine (BMAA) in ALS/PDC patients from Guam by Murch, S. J., Cox, P. A., Banack, S. A., Steele, J. C., Sacks, O. W.

“…We tested the brain tissues of the Chamorro people of Guam who died of amyotrophic lateral sclerosis/Parkinsonism dimentia complex (ALS/PDC) for the neurotoxin…”
Get full text

Amino acid neurotoxins in feathers of the Lesser Flamingo, Phoeniconaias minor by Metcalf, J.S., Banack, S.A., Kotut, K., Krienitz, L., Codd, G.A.

“…► The neurotoxins BMAA and DAB are deposited in Lesser Flamingo feathers. ► Using deuterated BMAA, good recoveries were obtained after SPE. ► DAB was found to…”
Get full text

Distinguishing the cyanobacterial neurotoxin β-N-methylamino-l-alanine (BMAA) from other diamino acids by Banack, S.A., Metcalf, J.S., Spáčil, Z., Downing, T.G., Downing, S., Long, A., Nunn, P.B., Cox, P.A.

“…β-N-methylamino-l-alanine (BMAA) is produced by diverse taxa of cyanobacteria, and has been detected by many investigators who have searched for it in…”
Get full text

Distinguishing the cyanobacterial neurotoxin β- N-methylamino- l-alanine (BMAA) from its structural isomer 2,4-diaminobutyric acid (2,4-DAB) by Banack, S.A., Downing, T.G., Spácil, Z., Purdie, E.L., Metcalf, J.S., Downing, S., Esterhuizen, M., Codd, G.A., Cox, P.A.

“…The cyanobacterial neurotoxin β- N-methylamino- l-alanine (BMAA) has been associated with certain forms of progressive neurodegenerative disease, including…”
Get full text

Toxin Analysis of Freshwater Cyanobacterial and Marine Harmful Algal Blooms on the West Coast of Florida and Implications for Estuarine Environments by Metcalf, J. S., Banack, S. A., Wessel, R. A., Lester, M., Pim, J. G., Cassani, J. R., Cox, P. A.

“…Recent marine and freshwater algal and cyanobacterial blooms in Florida have increased public concern and awareness of the risks posed by exposure to these…”
Get full text

L-Serine: a Naturally-Occurring Amino Acid with Therapeutic Potential by Metcalf, J. S., Dunlop, R. A., Powell, J. T., Banack, S. A., Cox, P. A.

“…In human neuroblastoma cell cultures, non-human primates and human beings, L-serine is neuroprotective, acting through a variety of biochemical and molecular…”
Get full text

Is Exposure to BMAA a Risk Factor for Neurodegenerative Diseases? A Response to a Critical Review of the BMAA Hypothesis by RA, Dunlop, SA, Banack, SL, Bishop, JS, Metcalf, SJ, Murch, DA, Davis, EW, Stommel, O, Karlsson, EB, Brittebo, AD, Chatziefthimiou, VX, Tan, GG, Guillemin, PA, Cox, DC, Mash, WG, Bradley

“…In a literature survey, Chernoff et al. ( 2017 ) dismissed the hypothesis that chronic exposure to β- N -methylamino-L-alanine (BMAA) may be a risk factor for…”
Get full text

Cyanotoxin Analysis and Amino Acid Profiles of Cyanobacterial Food Items from Chad by Metcalf, J. S., Dunlop, R. A., Banack, S. A., Souza, N. R., Cox, P. A.

“…In some parts of the world, cyanobacteria are used as a food in the human diet, due to their ready availability. Lake Chad, has long been a traditional site…”
Get full text

Microcystins, BMAA and BMAA isomers in 100-year-old Antarctic cyanobacterial mats collected during Captain R.F. Scott’s Discovery Expedition by Jungblut, A.D., Wilbraham, J., Banack, S.A., Metcalf, J.S., Codd, G.A.

“…Microcystins (MCN), [beta]-N-methylamino-L-alanine (BMAA) and anatoxin-a were investigated in Antarctic cyanobacterial mats collected from Ross Island and the…”
Get full text

Neurotoxic amino acids and their isomers in desert environments by Metcalf, J.S., Banack, S.A., Richer, R., Cox, P.A.

“…Cyanobacteria are capable of producing a wide range of bioactive compounds including highly toxic molecules which affect a variety of molecular targets. These…”
Get full text

Diet Selection and Resource Use by Flying Foxes (Genus Pteropus) by Banack, Sandra Anne

“…Flying foxes of the genus Pteropus (Pteropodidae: Chiroptera) play important roles as pollinators and seed dispersers in oceanic-island forest communities…”
Get full text

Biomagnification of cycad neurotoxins in flying foxes: implications for ALS-PDC in Guam by Banack, Sandra Anne, Cox, Paul Alan

“…Beta-methylamino-L-alanine (BMAA) occurs in higher levels in museum specimens of the Guamanian flying fox than in the cycad seeds the flying foxes feed on,…”
Get full text

Detection of cyanobacterial neurotoxin β-N-methylamino-l-alanine within shellfish in the diet of an ALS patient in Florida by Banack, Sandra Anne, Metcalf, James S., Bradley, Walter G., Cox, Paul Alan

“…Cyanobacteria produce the neurotoxic amino acid β-N-methylamino-l-alanine (BMAA), which in contaminated marine waters has been found to accumulate in…”
Get full text

Transfer of developmental neurotoxin β-N-methylamino-l-alanine (BMAA) via milk to nursed offspring: Studies by mass spectrometry and image analysis by Andersson, Marie, Karlsson, Oskar, Banack, Sandra Anne, Brandt, Ingvar

“…•Mass spectrometry (LC–MS/MS) showed that BMAA was transferred from lactating rats, via the milk, to nursed offspring.•No association to milk protein was…”
Get full text

mechanism for slow release of biomagnified cyanobacterial neurotoxins and neurodegenerative disease in Guam by Murch, S.J, Cox, P.A, Banack, S.A

“…As root symbionts of cycad trees, cyanobacteria of the genus Nostoc produce β-methylamino-L-alanine (BMAA), a neurotoxic nonprotein amino acid. The…”
Get full text

Diverse Taxa of Cyanobacteria Produce β-N-Methylamino-L-Alanine, a Neurotoxic Amino Acid by Cox, Paul Alan, Banack, Sandra Anne, Murch, Susan J., Rasmussen, Ulla, Tien, Georgia, Bidigare, Robert Richard, Metcalf, James S., Morrison, Louise F., Codd, Geoffrey A., Bergman, Birgitta, Bowers, William S.

“…Cyanobacteria can generate molecules hazardous to human health, but production of the known cyanotoxins is taxonomically sporadic. For example, members of a…”
Get full text

Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam by Cox, P.A, Banack, S.A, Murch, S.J

“…We here report biomagnification (the increasing accumulation of bioactive, often deleterious molecules through higher trophic levels of a food chain) of the…”
Get full text

Production of the neurotoxin BMAA by a marine cyanobacterium by Banack, Sandra Anne, Johnson, Holly E, Cheng, Ran, Cox, Paul Alan

“…Diverse species of cyanobacteria have recently been discovered to produce the neurotoxic non-protein amino acid beta-methylamino-L-alanine (BMAA). In Guam,…”
Get full text