Search Results - "Bammler, Theodor K."

Uterine overdistention induces preterm labor mediated by inflammation: observations in pregnant women and nonhuman primates by Adams Waldorf, Kristina M., MD, Singh, Natasha, MBBS, MRCOG, BSCCP, Mohan, Aarthi R., MD, PhD, Young, Roger C., MD, PhD, Ngo, Lisa, BS, Das, Ananya, MSc, Tsai, Jesse, BS, Bansal, Aasthaa, PhD, Paolella, Louis, BS, Herbert, Bronwen R., BSc, PhD, Sooranna, Suren R., PhD, Gough, G. Michael, MSc, Astley, Cliff, MS, Vogel, Keith, DVM, Baldessari, Audrey E., DVM, Bammler, Theodor K., PhD, MacDonald, James, MSc, Gravett, Michael G., MD, Rajagopal, Lakshmi, PhD, Johnson, Mark R., MD, PhD

“…Objective Uterine overdistention is thought to induce preterm labor in women with twin and multiple pregnancies, but the pathophysiology remains unclear. We…”
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The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner by Kisby, Glen E, Fry, Rebecca C, Lasarev, Michael R, Bammler, Theodor K, Beyer, Richard P, Churchwell, Mona, Doerge, Daniel R, Meira, Lisiane B, Palmer, Valerie S, Ramos-Crawford, Ana-Luiza, Ren, Xuefeng, Sullivan, Robert C, Kavanagh, Terrance J, Samson, Leona D, Zarbl, Helmut, Spencer, Peter S

“…Methylazoxymethanol (MAM), the genotoxic metabolite of the cycad azoxyglucoside cycasin, induces genetic alterations in bacteria, yeast, plants, insects and…”
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Genetic Polymorphisms of Catechol-O-Methyltransferase Modify the Neurobehavioral Effects of Mercury in Children by Woods, James S., Heyer, Nicholas J., Russo, Joan E., Martin, Michael D., Pillai, Pradeep B., Bammler, Theodor K., Farin, Federico M.

“…Mercury (Hg) is neurotoxic and children may be particularly susceptible to this effect. A current major challenge is identification of children who may be…”
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The pulmonary inflammatory response to multiwalled carbon nanotubes is influenced by gender and glutathione synthesis by Cartwright, Megan M, Schmuck, Stefanie C, Corredor, Charlie, Wang, Bingbing, Scoville, David K, Chisholm, Claire R, Wilkerson, Hui-Wen, Afsharinejad, Zahra, Bammler, Theodor K, Posner, Jonathan D, Shutthanandan, Vaithiyalingam, Baer, Donald R, Mitra, Somenath, Altemeier, William A, Kavanagh, Terrance J

“…Inhalation of multiwalled carbon nanotubes (MWCNTs) during their manufacture or incorporation into various commercial products may cause lung inflammation,…”
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A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging by McCormick, Mark A., Delaney, Joe R., Tsuchiya, Mitsuhiro, Tsuchiyama, Scott, Shemorry, Anna, Sim, Sylvia, Chou, Annie Chia-Zong, Ahmed, Umema, Carr, Daniel, Murakami, Christopher J., Schleit, Jennifer, Sutphin, George L., Wasko, Brian M., Bennett, Christopher F., Wang, Adrienne M., Olsen, Brady, Beyer, Richard P., Bammler, Theodor K., Prunkard, Donna, Johnson, Simon C., Pennypacker, Juniper K., An, Elroy, Anies, Arieanna, Castanza, Anthony S., Choi, Eunice, Dang, Nick, Enerio, Shiena, Fletcher, Marissa, Fox, Lindsay, Goswami, Sarani, Higgins, Sean A., Holmberg, Molly A., Hu, Di, Hui, Jessica, Jelic, Monika, Jeong, Ki-Soo, Johnston, Elijah, Kerr, Emily O., Kim, Jin, Kim, Diana, Kirkland, Katie, Klum, Shannon, Kotireddy, Soumya, Liao, Eric, Lim, Michael, Lin, Michael S., Lo, Winston C., Lockshon, Dan, Miller, Hillary A., Moller, Richard M., Muller, Brian, Oakes, Jonathan, Pak, Diana N., Peng, Zhao Jun, Pham, Kim M., Pollard, Tom G., Pradeep, Prarthana, Pruett, Dillon, Rai, Dilreet, Robison, Brett, Rodriguez, Ariana A., Ros, Bopharoth, Sage, Michael, Singh, Manpreet K., Smith, Erica D., Snead, Katie, Solanky, Amrita, Spector, Benjamin L., Steffen, Kristan K., Tchao, Bie Nga, Ting, Marc K., Vander Wende, Helen, Wang, Dennis, Welton, K. Linnea, Westman, Eric A., Brem, Rachel B., Liu, Xin-guang, Suh, Yousin, Zhou, Zhongjun, Kaeberlein, Matt, Kennedy, Brian K.

“…Many genes that affect replicative lifespan (RLS) in the budding yeast Saccharomyces cerevisiae also affect aging in other organisms such as C. elegans and…”
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MicroRNA Signature of Epithelial-Mesenchymal Transition in Group B Streptococcal Infection of the Placental Chorioamniotic Membranes by Weed, Samantha, Armistead, Blair, Coleman, Michelle, Liggit, H Denny, Johnson, Brian, Tsai, Jesse, Beyer, Richard P, Bammler, Theodor K, Kretzer, Nicole M, Parker, Ed, Vanderhoeven, Jeroen P, Bierle, Craig J, Rajagopal, Lakshmi, Adams Waldorf, Kristina M

“…Abstract Background Infection-induced preterm birth is a major cause of neonatal mortality and morbidity and leads to preterm premature rupture of placental…”
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Evidence of cardiac involvement in the fetal inflammatory response syndrome: disruption of gene networks programming cardiac development in nonhuman primates by Mitchell, Timothy, MacDonald, James W., Srinouanpranchanh, Sengkeo, Bammler, Theodor K., Merillat, Sean, Boldenow, Erica, Coleman, Michelle, Agnew, Kathy, Baldessari, Audrey, Stencel-Baerenwald, Jennifer E., Tisoncik-Go, Jennifer, Green, Richard R., Gale, Michael J., Rajagopal, Lakshmi, Adams Waldorf, Kristina M.

“…Most early preterm births are associated with intraamniotic infection and inflammation, which can lead to systemic inflammation in the fetus. The fetal…”
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Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age by Mason, Amanda G, Tomé, Stephanie, Simard, Jodie P, Libby, Randell T, Bammler, Theodor K, Beyer, Richard P, Morton, A Jennifer, Pearson, Christopher E, La Spada, Albert R

“…Expansion of CAG/CTG trinucleotide repeats causes numerous inherited neurological disorders, including Huntington's disease (HD), several spinocerebellar…”
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Paracrine activation of hepatic stellate cells in platelet‐derived growth factor C transgenic mice: Evidence for stromal induction of hepatocellular carcinoma by Wright, Jocelyn H., Johnson, Melissa M., Shimizu‐Albergine, Masami, Bauer, Renay L., Hayes, Brian J., Surapisitchat, James, Hudkins, Kelly L., Riehle, Kimberly J., Johnson, Simon C., Yeh, Matthew M., Bammler, Theodor K., Beyer, Richard P., Gilbertson, Debra G., Alpers, Charles E., Fausto, Nelson, Campbell, Jean S.

“…Cirrhosis is the primary risk factor for the development of hepatocellular carcinoma (HCC), yet the mechanisms by which cirrhosis predisposes to carcinogenesis…”
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Transcriptional analysis of human cranial compartments with different embryonic origins by Homayounfar, Negar, Park, Sarah S, Afsharinejad, Zahra, Bammler, Theodor K, MacDonald, James W, Farin, Federico M, Mecham, Brigham H, Cunningham, Michael L

“…Highlights • Signature of embryonic origins in human calvarial compartments was evaluated. • Global gene expression of these compartments was tested. • In pair…”
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Recombinant erythropoietin is neuroprotective in a novel mouse oxidative injury model by Juul, Sandra E, McPherson, Ronald J, Bammler, Theodor K, Wilkerson, Jasmine, Beyer, Richard P, Farin, Federico M

“…To identify neuroprotective changes in gene expression, we developed a neonatal mouse model of moderate to severe oxidative brain injury and hypothesized that…”
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CHF1/Hey2 promotes physiological hypertrophy in response to pressure overload through selective repression and activation of specific transcriptional pathways by Yu, Man, Liu, Yonggang, Xiang, Fan, Li, Yuxin, Cullen, Darragh, Liao, Ronglih, Beyer, Richard P, Bammler, Theodor K, Chin, Michael T

“…We have previously found that CHF1/Hey2 prevents the development of phenylephrine-induced cardiac hypertrophy. To determine the role of CHF1/Hey2 in pressure…”
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Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1α in Huntington's disease neurodegeneration by Weydt, Patrick, Pineda, Victor V., Torrence, Anne E., Libby, Randell T., Satterfield, Terrence F., Lazarowski, Eduardo R., Gilbert, Merle L., Morton, Gregory J., Bammler, Theodor K., Strand, Andrew D., Cui, Libin, Beyer, Richard P., Easley, Courtney N., Smith, Annette C., Krainc, Dimitri, Luquet, Serge, Sweet, Ian R., Schwartz, Michael W., La Spada, Albert R.

“…Huntington's disease (HD) is a fatal, dominantly inherited disorder caused by polyglutamine repeat expansion in the huntingtin (htt) gene. Here, we observe…”
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Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration by Weydt, Patrick, Pineda, Victor V, Torrence, Anne E, Libby, Randell T, Satterfield, Terrence F, Lazarowski, Eduardo R, Gilbert, Merle L, Morton, Gregory J, Bammler, Theodor K, Strand, Andrew D, Cui, Libin, Beyer, Richard P, Easley, Courtney N, Smith, Annette C, Krainc, Dimitri, Luquet, Serge, Sweet, Ian R, Schwartz, Michael W, La Spada, Albert R

“…Huntington's disease (HD) is a fatal, dominantly inherited disorder caused by polyglutamine repeat expansion in the huntingtin (htt) gene. Here, we observe…”
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Isolation and characterization of two murine p1-class glutathione s-transferases by Bammler, Theodor K

“…A 15-kilobase (kb) DNA fragment has been isolated from a mouse genomic library in λEMBL3 that contains two actively transcribed pi-class GST genes termed Gst…”
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Differential single- versus double-strand DNA breakage produced by doxorubicin and its morpholinyl analogues by DURAN, G. E, LAU, D. H. M, LEWIS, A. D, KÜHL, J.-S, BÄMMLER, T. K, SIKIC, B. I

“…The morpholinyl analogues of doxorubicin (DOX) have previously been reported to be non-cross-resistant in multidrug resistant (MDR) cells due to a lower…”
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