Search Results - "Bamford, Natalie C"

Bacillus subtilis biofilm formation and social interactions by Arnaouteli, Sofia, Bamford, Natalie C., Stanley-Wall, Nicola R., Kovács, Ákos T.

“…Biofilm formation is a process in which microbial cells aggregate to form collectives that are embedded in a self-produced extracellular matrix. Bacillus…”
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TasA Fibre Interactions Are Necessary for Bacillus subtilis Biofilm Structure by Bamford, Natalie C, Morris, Ryan J, Prescott, Alan, Murphy, Paul, Erskine, Elliot, MacPhee, Cait E, Stanley-Wall, Nicola R

“…The extracellular matrix of biofilms provides crucial structural support to the community and protection from environmental perturbations. TasA, a key Bacillus…”
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Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases by Le Mauff, François, Bamford, Natalie C., Alnabelseya, Noor, Zhang, Yongzhen, Baker, Perrin, Robinson, Howard, Codée, Jeroen D.C., Howell, P. Lynne, Sheppard, Donald C.

“…During infection, the fungal pathogen Aspergillus fumigatus forms biofilms that enhance its resistance to antimicrobials and host defenses. An integral…”
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PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β(1,6)-N-acetylglucosamine and can disrupt bacterial biofilms by Little, Dustin J, Pfoh, Roland, Le Mauff, François, Bamford, Natalie C, Notte, Christina, Baker, Perrin, Guragain, Manita, Robinson, Howard, Pier, Gerald B, Nitz, Mark, Deora, Rajendar, Sheppard, Donald C, Howell, P Lynne

“…Poly-β(1,6)-N-acetyl-D-glucosamine (PNAG) is a major biofilm component of many pathogenic bacteria. The production, modification, and export of PNAG in…”
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Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation by Bamford, Natalie C., Le Mauff, François, Van Loon, Jaime C., Ostapska, Hanna, Snarr, Brendan D., Zhang, Yongzhen, Kitova, Elena N., Klassen, John S., Codée, Jeroen D. C., Sheppard, Donald C., Howell, P. Lynne

“…The exopolysaccharide galactosaminogalactan (GAG) is an important virulence factor of the fungal pathogen Aspergillus fumigatus . Deletion of a gene encoding a…”
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Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation by Lee, Mark J, Geller, Alexander M, Bamford, Natalie C, Liu, Hong, Gravelat, Fabrice N, Snarr, Brendan D, Le Mauff, François, Chabot, Joseé, Ralph, Benjamin, Ostapska, Hanna, Lehoux, Mélanie, Cerone, Robert P, Baptista, Stephanie D, Vinogradov, Evgeny, Stajich, Jason E, Filler, Scott G, Howell, P Lynne, Sheppard, Donald C

“…The mold Aspergillus fumigatus causes invasive infection in immunocompromised patients. Recently, galactosaminogalactan (GAG), an exopolysaccharide composed of…”
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Modification and periplasmic translocation of the biofilm exopolysaccharide poly-β-1,6-N-acetyl-D-glucosamine by Little, Dustin J., Li, Grace, Ing, Christopher, DiFrancesco, Benjamin R., Bamford, Natalie C., Robinson, Howard, Nitz, Mark, Pomès, Régis, Howell, P. Lynne

“…Poly-β-1,6-N-acetyl-D-glucosamine (PNAG) is an exopolysaccharide produced by a wide variety of medically important bacteria. Poly-glucosamine subunit B (PgaB)…”
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Preclinical Evaluation of Recombinant Microbial Glycoside Hydrolases in the Prevention of Experimental Invasive Aspergillosis by Ostapska, Hanna, Raju, Deepa, Lehoux, Melanie, Lacdao, Ira, Gilbert, Stephanie, Sivarajah, Piyanka, Bamford, Natalie C, Baker, Perrin, Nguyen, Thi Tuyet Mai, Zacharias, Caitlin A, Gravelat, Fabrice N, Howell, P Lynne, Sheppard, Donald C

“…Aspergillus fumigatus is a ubiquitous mold that can cause invasive pulmonary infections in immunocompromised patients. Within the lung, A. fumigatus forms…”
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Co-Operative Biofilm Interactions between Aspergillus fumigatus and Pseudomonas aeruginosa through Secreted Galactosaminogalactan Exopolysaccharide by Ostapska, Hanna, Le Mauff, François, Gravelat, Fabrice N, Snarr, Brendan D, Bamford, Natalie C, Van Loon, Jaime C, McKay, Geoffrey, Nguyen, Dao, Howell, P Lynne, Sheppard, Donald C

“…The mold and bacterium form biofilms in the airways of individuals with cystic fibrosis. Biofilm formation by depends on the self-produced cationic…”
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Microbial Primer: An introduction to biofilms - what they are, why they form and their impact on built and natural environments by Bamford, Natalie C, MacPhee, Cait E, Stanley-Wall, Nicola R

“…Biofilms are complex communities of microbes that are bound by an extracellular macromolecular matrix produced by the residents. Biofilms are the predominant…”
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Bacillus subtilis Matrix Protein TasA is Interfacially Active, but BslA Dominates Interfacial Film Properties by Morris, Ryan J., Bamford, Natalie C., Bromley, Keith M., Erskine, Elliot, Stanley-Wall, Nicola R., MacPhee, Cait E.

“…Microbial growth often occurs within multicellular communities called biofilms, where cells are enveloped by a protective extracellular matrix. Bacillus…”
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The majority of the matrix protein TapA is dispensable for Bacillus subtilis colony biofilm architecture by Earl, Chris, Arnaouteli, Sofia, Bamford, Natalie C., Porter, Michael, Sukhodub, Tetyana, MacPhee, Cait E., Stanley‐Wall, Nicola R.

“…Biofilm formation is a co‐operative behaviour, where microbial cells become embedded in an extracellular matrix. This biomolecular matrix helps manifest the…”
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Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity by Snarr, Brendan D., Baker, Perrin, Bamford, Natalie C., Sato, Yukiko, Liu, Hong, Lehoux, Mélanie, Gravelat, Fabrice N., Ostapska, Hanna, Baistrocchi, Shane R., Cerone, Robert P., Filler, Elan E., Parsek, Matthew R., Filler, Scott G., Howell, P. Lynne, Sheppard, Donald C.

“…Galactosaminogalactan and Pel are cationic heteropolysaccharides produced by the opportunistic pathogens Aspergillus fumigatus and Pseudomonas aeruginosa,…”
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Preclinical Evaluation of Recombinant Microbial Glycoside Hydrolases as Antibiofilm Agents in Acute Pulmonary Pseudomonas aeruginosa Infection by Ostapska, Hanna, Raju, Deepa, Corsini, Rachel, Lehoux, Melanie, Lacdao, Ira, Gilbert, Stephanie, Sivarajah, Piyanka, Bamford, Natalie C, Baker, Perrin, Gravelat, Fabrice N, Howell, P Lynne, Sheppard, Donald C

“…The bacterium Pseudomonas aeruginosa can colonize the airways of patients with chronic lung disease. Within the lung, P. aeruginosa forms biofilms that can…”
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Ega3 from the fungal pathogen Aspergillus fumigatus is an endo-α-1,4-galactosaminidase that disrupts microbial biofilms by Bamford, Natalie C., Le Mauff, François, Subramanian, Adithya S., Yip, Patrick, Millán, Claudia, Zhang, Yongzhen, Zacharias, Caitlin, Forman, Adam, Nitz, Mark, Codée, Jeroen D.C., Usón, Isabel, Sheppard, Donald C., Howell, P. Lynne

“…Aspergillus fumigatus is an opportunistic fungal pathogen that causes both chronic and acute invasive infections. Galactosaminogalactan (GAG) is an integral…”
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Lateral interactions govern self-assembly of the bacterial biofilm matrix protein BslA by Arnaouteli, Sofia, Bamford, Natalie C, Brandani, Giovanni B, Morris, Ryan J, Schor, Marieke, Carrington, Jamie T, Hobley, Laura, van Aalten, Daan M F, Stanley-Wall, Nicola R, MacPhee, Cait E

“…The soil bacterium is a model organism to investigate the formation of biofilms, the predominant form of microbial life. The secreted protein BslA…”
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Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus by Bamford, Natalie C., Snarr, Brendan D., Gravelat, Fabrice N., Little, Dustin J., Lee, Mark J., Zacharias, Caitlin A., Chabot, Josée C., Geller, Alexander M., Baptista, Stefanie D., Baker, Perrin, Robinson, Howard, Howell, P. Lynne, Sheppard, Donald C.

“…Aspergillus fumigatus is the most virulent species within the Aspergillus genus and causes invasive infections with high mortality rates. The exopolysaccharide…”
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Molecular Basis for the Attachment of S‑Layer Proteins to the Cell Wall of Bacillus anthracis by Sychantha, David, Chapman, Robert N, Bamford, Natalie C, Boons, Geert-Jan, Howell, P. Lynne, Clarke, Anthony J

“…Bacterial surface (S) layers are paracrystalline arrays of protein assembled on the bacterial cell wall that serve as protective barriers and scaffolds for…”
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The Protein BpsB Is a Poly-β-1,6-N-acetyl-d-glucosamine Deacetylase Required for Biofilm Formation in Bordetella bronchiseptica by Little, Dustin J., Milek, Sonja, Bamford, Natalie C., Ganguly, Tridib, DiFrancesco, Benjamin R., Nitz, Mark, Deora, Rajendar, Howell, P. Lynne

“…Bordetella pertussis and Bordetella bronchiseptica are the causative agents of whooping cough in humans and a variety of respiratory diseases in animals,…”
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Structural Basis for the De-N-acetylation of Poly-β-1,6-N-acetyl-d-glucosamine in Gram-positive Bacteria by Little, Dustin J., Bamford, Natalie C., Pokrovskaya, Varvara, Robinson, Howard, Nitz, Mark, Howell, P. Lynne

“…Exopolysaccharides are required for the development and integrity of biofilms produced by a wide variety of bacteria. In staphylococci, partial…”
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