Search Results - "Balzani, Edoardo"
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The development of synaptic transmission is time-locked to early social behaviors in rats
Published in Nature communications (13-03-2019)“…The development of functional synapses is a sequential process preserved across many brain areas. Here, we show that glutamatergic postsynaptic currents…”
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Context-invariant beliefs are supported by dynamic reconfiguration of single unit functional connectivity in prefrontal cortex of male macaques
Published in Nature communications (09-07-2024)“…Natural behaviors occur in closed action-perception loops and are supported by dynamic and flexible beliefs abstracted away from our immediate sensory milieu…”
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An approach to monitoring home-cage behavior in mice that facilitates data sharing
Published in Nature protocols (01-06-2018)“…Behavioral phenotyping is often a noisy process in mouse genetics. We developed a home-cage approach controlled by the Phenopy platform, which increases the…”
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Coding of latent variables in sensory, parietal, and frontal cortices during closed-loop virtual navigation
Published in eLife (25-10-2022)“…We do not understand how neural nodes operate and coordinate within the recurrent action-perception loops that characterize naturalistic self-environment…”
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Working-for-Food Behaviors: A Preclinical Study in Prader-Willi Mutant Mice
Published in Genetics (Austin) (01-11-2016)“…Abnormal feeding behavior is one of the main symptoms of Prader-Willi syndrome (PWS). By studying a PWS mouse mutant line, which carries a paternally inherited…”
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The Zfhx3-Mediated Axis Regulates Sleep and Interval Timing in Mice
Published in Cell reports (Cambridge) (19-07-2016)“…An AT motif-dependent axis, modulated by the transcription factor Zfhx3, influences the circadian clock in mice. In particular, gain of function of Zfhx3…”
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Cell-cell coupling and DNA methylation abnormal phenotypes in the after-hours mice
Published in Epigenetics & chromatin (06-01-2021)“…DNA methylation has emerged as an important epigenetic regulator of brain processes, including circadian rhythms. However, how DNA methylation intervenes…”
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Deletion of the Snord116/SNORD116 Alters Sleep in Mice and Patients with Prader-Willi Syndrome
Published in Sleep (New York, N.Y.) (01-03-2016)“…Sleep-wake disturbances are often reported in Prader-Willi syndrome (PWS), a rare neurodevelopmental syndrome that is associated with paternally-expressed…”
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The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis
Published in Scientific reports (19-12-2017)“…Circadian clock is known to adapt to environmental changes and can significantly influence cognitive and physiological functions. In this work, we report…”
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Loss of Snord116 impacts lateral hypothalamus, sleep, and food-related behaviors
Published in JCI insight (18-06-2020)“…Imprinted genes are highly expressed in the hypothalamus; however, whether specific imprinted genes affect hypothalamic neuromodulators and their functions is…”
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ODIN: Open Data In Neurophysiology: Advancements, Solutions & Challenges
Published 01-07-2024“…Across the life sciences, an ongoing effort over the last 50 years has made data and methods more reproducible and transparent. This openness has led to…”
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A probabilistic framework for task-aligned intra- and inter-area neural manifold estimation
Published 06-09-2022“…Latent manifolds provide a compact characterization of neural population activity and of shared co-variability across brain areas. Nonetheless, existing…”
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