Search Results - "Balzac, F"

Beta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in nonmuscle cells by Belkin, A M, Zhidkova, N I, Balzac, F, Altruda, F, Tomatis, D, Maier, A, Tarone, G, Koteliansky, V E, Burridge, K

“…The cytoplasmic domains of integrins provide attachment of these extracellular matrix receptors to the cytoskeleton and play a critical role in…”
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Integrin function and regulation in development by Tarone, G, Hirsch, E, Brancaccio, M, De Acetis, M, Barberis, L, Balzac, F, Retta, S F, Botta, C, Altruda, F, Silengo, L, Retta, F

“…Integrins are a large family of membrane receptors, consisting of alpha and beta subunits, that play a pivotal role in the interaction of cells with the…”
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Expression of beta 1B integrin isoform in CHO cells results in a dominant negative effect on cell adhesion and motility by Balzac, F, Retta, S F, Albini, A, Melchiorri, A, Koteliansky, V E, Geuna, M, Silengo, L, Tarone, G

“…The integrin subunit beta 1B, a beta 1 isoform with a unique sequence at the cytoplasmic domain, forms heterodimers with integrin alpha chains and binds…”
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Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2‐neo mouse rescued by L‐type calcium channel blockers by Calorio, Chiara, Gavello, Daniela, Guarina, Laura, Salio, Chiara, Sassoè‐Pognetto, Marco, Riganti, Chiara, Bianchi, Federico Tommaso, Hofer, Nadja T., Tuluc, Petronel, Obermair, Gerald J., Defilippi, Paola, Balzac, Fiorella, Turco, Emilia, Bett, Glenna C., Rasmusson, Randall L., Carbone, Emilio

“…Key points Tymothy syndrome (TS) is a multisystem disorder featuring cardiac arrhythmias, autism and adrenal gland dysfunction that originates from a de novo…”
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E-cadherin endocytosis regulates the activity of Rap1: a traffic light GTPase at the crossroads between cadherin and integrin function by Balzac, Fiorella, Avolio, Maria, Degani, Simona, Kaverina, Irina, Torti, Mauro, Silengo, Lorenzo, Small, J. Victor, Retta, Saverio Francesco

“…The coordinate modulation of cadherin and integrin functions plays an essential role in fundamental physiological and pathological processes, including…”
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Rap1: A turnabout for the crosstalk between cadherins and integrins by Retta, Saverio Francesco, Balzac, Fiorella, Avolio, Maria

“…The coordinate modulation of the cellular functions of cadherins and integrins plays an essential role in fundamental physiological and pathological processes,…”
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The Integrin Cytoplasmic Domain-Associated Protein ICAP-1 Binds and Regulates Rho Family GTPases during Cell Spreading by Degani, Simona, Balzac, Fiorella, Brancaccio, Mara, Guazzone, Simona, Retta, Saverio Francesco, Silengo, Lorenzo, Eva, Alessandra, Tarone, Guido

“…Using two-hybrid screening, we isolated the integrin cytoplasmic domain-associated protein (ICAP-1), an interactor for the COOH terminal region of the β1A…”
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Identification of Krit1B: a novel alternative splicing isoform of cerebral cavernous malformation gene-1 by Retta, Saverio Francesco, Avolio, Maria, Francalanci, Floriana, Procida, Simone, Balzac, Fiorella, Degani, Simona, Tarone, Guido, Silengo, Lorenzo

“…Cerebral cavernous malformations (CCM) are vascular malformations, mostly located in the central nervous system, which occur in 0.1–0.5% of the population…”
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αv Integrin subunit is predominantly located in nervous tissue and skeletal muscle during mouse development by Hirsch, Emilio, Gullberg, Donald, Balzac, Fiorella, Altruda, Fiorella, Silengo, Lorenzo, Tarone, Guido

“…αv integrin subunit can dimerize with different β subunits to form receptors for several matrix proteins. The function of these receptors in vivo is still…”
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Expression and functional analysis of a cytoplasmic domain variant of the beta 1 integrin subunit by Balzac, F, Belkin, A M, Koteliansky, V E, Balabanov, Y V, Altruda, F, Silengo, L, Tarone, G

“…We have previously described a variant form of the integrin beta 1 subunit (beta 1B)1 characterized by an altered sequence at the cytoplasmic domain. Using…”
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Expression, topography, and function of integrin receptors are severely altered in keratinocytes from involved and uninvolved psoriatic skin by Pellegrini, G, De Luca, M, Orecchia, G, Balzac, F, Cremona, O, Savoia, P, Cancedda, R, Marchisio, P C

“…Psoriasis is a hyperproliferative cutaneous disease of unknown etiology and etiopathogenesis. Alteration of keratinocyte adhesiveness to basal lamina has been…”
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Expression and Functional Analysis of a Cytoplasmic Domain Variant of the β1 Integrin Subunit by Balzac, Fiorella, Belkin, Alexey M., Koteliansky, Victor E., Balabanov, Yuri V., Altruda, Fiorella, Silengo, Lorenzo, Tarone, Guido

“…We have previously described a variant form of the integrin β1 subunit (β 1B)1 characterized by an altered sequence at the cytoplasmic domain. Using polyclonal…”
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The muscle-specific laminin receptor alpha7 beta1 integrin negatively regulates alpha5 beta1 fibronectin receptor function by Tomatis, D, Echtermayer, F, Schöber, S, Balzac, F, Retta, S F, Silengo, L, Tarone, G

“…alpha7 beta1 is the major integrin complex expressed in differentiated muscle cells where it functions as a laminin receptor. In this work we have expressed…”
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beta1-integrin cytoplasmic subdomains involved in dominant negative function by Retta, S F, Balzac, F, Ferraris, P, Belkin, A M, Fässler, R, Humphries, M J, De Leo, G, Silengo, L, Tarone, G

“…The beta1-integrin cytoplasmic domain consists of a membrane proximal subdomain common to the four known isoforms ("common" region) and a distal subdomain…”
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Muscle beta1D integrin reinforces the cytoskeleton-matrix link: modulation of integrin adhesive function by alternative splicing by Belkin, A M, Retta, S F, Pletjushkina, O Y, Balzac, F, Silengo, L, Fassler, R, Koteliansky, V E, Burridge, K, Tarone, G

“…Expression of muscle-specific beta1D integrin with an alternatively spliced cytoplasmic domain in CHO and GD25, beta1 integrin-minus cells leads to their…”
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Internalization of the alpha 5 beta 1 integrin does not depend on "NPXY" signals by Vignoud, L, Usson, Y, Balzac, F, Tarone, G, Block, M R

“…The alpha 5 beta 1 integrin is a constitutively internalized fibronectin receptor. It contains in the cytoplasmic tail of its beta 1 subunit two NPXY sequences…”
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Expression, topography, and function of integrin receptors are severely altered in keratinocytes from involved and uninvolved psoriatic skin by Pellegrini, G, de Luca, M, Orecchia, G, Balzac, F, Cremona, O, Savoia, P, Cancedda, R, Marchisio, P C

“…Psoriasis is a hyperproliferative cutaneous disease of unknown etiology and etiopathogenesis. Alteration of keratinocyte adhesiveness to basal lamina has been…”
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Expression, topography, and fucntion of integrin receptors are severely altered in keratinocytes from involved and uninvolved psoriatic skin by PELLEGRINI, G, DE LUCA, M, ORECCHIA, G, BALZAC, F, CREMONA, O, SAVOIA, P, CANCEDDA, R, PIER CARLO MARCHISIO

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A human integrin beta 1 subunit with a unique cytoplasmic domain generated by alternative mRNA processing by Altruda, F, Cervella, P, Tarone, G, Botta, C, Balzac, F, Stefanuto, G, Silengo, L

“…The integrin subunit (beta 1) is common to a group of plasma membrane glycoprotein heterodimers that include the fibronectin, laminin and collagen receptors…”
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Primary cultures of corticostriatal cells from newborn rats: a model to study muscarinic receptor subtypes regulation and function by Eva, C, Bovolin, P, Balzac, F, Botta, C, Gamalero, S R, Vaccarino, F M

“…In the present work we characterized both the presynaptic and postsynaptic components of cholinergic transmission in a primary culture of corticostriatal…”
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