Search Results - "Baltuch, Gordon H"

A Randomized Sham-Controlled Trial of Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Chronic Treatment-Resistant Depression by Dougherty, Darin D, Rezai, Ali R, Carpenter, Linda L, Howland, Robert H, Bhati, Mahendra T, O’Reardon, John P, Eskandar, Emad N, Baltuch, Gordon H, Machado, Andre D, Kondziolka, Douglas, Cusin, Cristina, Evans, Karleyton C, Price, Lawrence H, Jacobs, Karen, Pandya, Mayur, Denko, Timothey, Tyrka, Audrey R, Brelje, Tim, Deckersbach, Thilo, Kubu, Cynthia, Malone, Donald A

“…Abstract Background Multiple open-label trials of deep brain stimulation (DBS) for treatment-resistant depression (TRD), including those targeting the ventral…”
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Long-term outcomes following deep brain stimulation for Parkinson's disease by Hitti, Frederick L, Ramayya, Ashwin G, McShane, Brendan J, Yang, Andrew I, Vaughan, Kerry A, Baltuch, Gordon H

“…OBJECTIVE: Deep brain stimulation (DBS) is an effective treatment for several movement disorders, including Parkinson's disease (PD). While this treatment has…”
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Oscillatory patterns in temporal lobe reveal context reinstatement during memory search by Manning, Jeremy R., Polyn, Sean M., Baltuch, Gordon H., Litt, Brian, Kahana, Michael J.

“…Psychological theories of memory posit that when people recall a past event, they not only recover the features of the event itself, but also recover…”
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Subthalamic deep brain stimulation with a constant-current device in Parkinson's disease: an open-label randomised controlled trial by Okun, Michael S, Dr, Gallo, Bruno V, MD, Mandybur, George, MD, Jagid, Jonathan, MD, Foote, Kelly D, MD, Revilla, Fredy J, MD, Alterman, Ron, MD, Jankovic, Joseph, MD, Simpson, Richard, MD, Junn, Fred, MD, Verhagen, Leo, MD, Arle, Jeff E, MD, Ford, Blair, MD, Goodman, Robert R, MD, Stewart, R Malcolm, MD, Horn, Stacy, DO, Baltuch, Gordon H, MD, Kopell, Brian H, MD, Marshall, Frederick, MD, Peichel, DeLea, BS, Pahwa, Rajesh, MD, Lyons, Kelly E, PhD, Tröster, Alexander I, PhD, Vitek, Jerrold L, MD, Tagliati, Michele, MD

“…Summary Background The effects of constant-current deep brain stimulation (DBS) have not been studied in controlled trials in patients with Parkinson's…”
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Human Substantia Nigra Neurons Encode Unexpected Financial Rewards by Zaghloul, Kareem A, Blanco, Justin A, Weidemann, Christoph T, McGill, Kathryn, Jaggi, Jurg L, Baltuch, Gordon H, Kahana, Michael J

“…The brain's sensitivity to unexpected outcomes plays a fundamental role in an organism's ability to adapt and learn new behaviors. Emerging research suggests…”
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Neuronal activity in the human subthalamic nucleus encodes decision conflict during action selection by Zaghloul, Kareem A, Weidemann, Christoph T, Lega, Bradley C, Jaggi, Jurg L, Baltuch, Gordon H, Kahana, Michael J

“…The subthalamic nucleus (STN), which receives excitatory inputs from the cortex and has direct connections with the inhibitory pathways of the basal ganglia,…”
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Deep brain stimulation in the treatment of refractory epilepsy: Update on current data and future directions by Lega, Bradley C, Halpern, Casey H, Jaggi, Jurg L, Baltuch, Gordon H

“…Abstract Deep brain stimulation for epilepsy has garnered attention from epileptologists due to its well-documented success in treating movement disorders and…”
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Pervasive within-Mitochondrion Single-Nucleotide Variant Heteroplasmy as Revealed by Single-Mitochondrion Sequencing by Morris, Jacqueline, Na, Young-Ji, Zhu, Hua, Lee, Jae-Hee, Giang, Hoa, Ulyanova, Alexandra V., Baltuch, Gordon H., Brem, Steven, Chen, H. Isaac, Kung, David K., Lucas, Timothy H., O’Rourke, Donald M., Wolf, John A., Grady, M. Sean, Sul, Jai-Yoon, Kim, Junhyong, Eberwine, James

“…A number of mitochondrial diseases arise from single-nucleotide variant (SNV) accumulation in multiple mitochondria. Here, we present a method for…”
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Primary Cell Culture of Live Neurosurgically Resected Aged Adult Human Brain Cells and Single Cell Transcriptomics by Spaethling, Jennifer M., Na, Young-Ji, Lee, Jaehee, Ulyanova, Alexandra V., Baltuch, Gordon H., Bell, Thomas J., Brem, Steven, Chen, H. Isaac, Dueck, Hannah, Fisher, Stephen A., Garcia, Marcela P., Khaladkar, Mugdha, Kung, David K., Lucas, Timothy H., O’Rourke, Donald M., Stefanik, Derek, Wang, Jinhui, Wolf, John A., Bartfai, Tamas, Grady, M. Sean, Sul, Jai-Yoon, Kim, Junhyong, Eberwine, James H.

“…Investigation of human CNS disease and drug effects has been hampered by the lack of a system that enables single-cell analysis of live adult patient brain…”
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Deep brain stimulation in the treatment of obesity by HALPERN, Casey H, WOLF, John A, BALE, Tracy L, STUNKARD, Albert J, DANISH, Shabbar F, GROSSMAN, Murray, JAGGI, Jurg L, GRADY, M. Sean, BALTUCH, Gordon H

“…Obesity is a growing global health problem frequently intractable to current treatment options. Recent evidence suggests that deep brain stimulation (DBS) may…”
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Subthalamic nucleus deep brain stimulation for severe idiopathic dystonia : impact on severity, neuropsychological status, and quality of life by KLEINER-FISMAN, Galit, LIN LIANG, Grace S, MOBERG, Paul J, RUOCCO, Anthony C, HURTIG, Howard I, BALTUCH, Gordon H, JAGGI, Jurg L, STERN, Matthew B

“…Medically refractory dystonia has recently been treated using deep brain stimulation (DBS) targeting the globus pallidus internus (GPI). Outcomes have varied…”
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Brain shift during deep brain stimulation surgery for Parkinson's disease by Halpern, Casey H, Danish, Shabbar F, Baltuch, Gordon H, Jaggi, Jurg L

“…Brain shift may occur during deep brain stimulation (DBS) surgery, which may affect the position of subcortical structures, compromising target localization…”
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Neuronal and oscillatory activity during reward processing in the human ventral striatum by Lega, Bradley C, Kahana, Michael J, Jaggi, Jurg, Baltuch, Gordon H, Zaghloul, Kareem

“…Accumulated evidence from animal studies implicates the ventral striatum in the processing of reward information. Recently, deep brain stimulation (DBS)…”
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Deep brain stimulation for movement disorders: morbidity and mortality in 109 patients by UMEMURA, Atsushi, JAGGI, Jurg L, HURTIG, Howard I, SIDEROWF, Andrew D, COLCHER, Amy, STERN, Matthew B, BALTUCH, Gordon H

“…Deep brain stimulation (DBS) has been advocated as a more highly effective and less morbidity-producing alternative to ablative stereotactic surgery in the…”
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Proximity of Substantia Nigra Microstimulation to Putative GABAergic Neurons Predicts Modulation of Human Reinforcement Learning by Ramayya, Ashwin G, Pedisich, Isaac, Levy, Deborah, Lyalenko, Anastasia, Wanda, Paul, Rizzuto, Daniel, Baltuch, Gordon H, Kahana, Michael J

“…Neuronal firing in the substantia nigra (SN) immediately following reward is thought to play a crucial role in human reinforcement learning. As in Ramayya et…”
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Electrophysiological evidence for functionally distinct neuronal populations in the human substantia nigra by Ramayya, Ashwin G, Zaghloul, Kareem A, Weidemann, Christoph T, Baltuch, Gordon H, Kahana, Michael J

“…The human substantia nigra (SN) is thought to consist of two functionally distinct neuronal populations-dopaminergic (DA) neurons in the pars compacta…”
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Expanding applications of deep brain stimulation: a potential therapeutic role in obesity and addiction management by Halpern, Casey H., Torres, Napoleon, Hurtig, Howard I., Wolf, John A., Stephen, James, Oh, Michael Y., Williams, Noel N., Dichter, Marc A., Jaggi, Jurg L., Caplan, Arthur L., Kampman, Kyle M., Wadden, Thomas A., Whiting, Donald M., Baltuch, Gordon H.

“…Background The indications for deep brain stimulation (DBS) are expanding, and the feasibility and efficacy of this surgical procedure in various neurologic…”
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Self-administered preoperative antiseptic wash to prevent postoperative infection after deep brain stimulation by Halpern, Casey H., MD, Mitchell, Grant W., BS, Paul, Aaron, MD, Kramer, Daniel R., BS, McGill, Kathryn R., MSN, APN, Buonacuore, Dana, MSN, APN, Kerr, Marie, CCRP, Jaggi, Jurg L., PhD, Stern, John J., MD, Baltuch, Gordon H., MD, PhD

“…Background Prevention of surgical site infections is critical in deep brain stimulation (DBS). In the present study, we tested the ability of a…”
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Bilateral subthalamic nucleus deep brain stimulation in a patient with cervical dystonia and essential tremor by Chou, Kelvin L., Hurtig, Howard I., Jaggi, Jurg L., Baltuch, Gordon H.

“…The role of subthalamic nucleus (STN) deep brain stimulation (DBS) is well established in Parkinson's disease, but experience with STN DBS in other movement…”
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Human gene therapy approaches for the treatment of Parkinson's disease: An overview of current and completed clinical trials by Hitti, Frederick L., Yang, Andrew I., Gonzalez-Alegre, Pedro, Baltuch, Gordon H.

“…Gene therapy has been employed in the human brain for a number of disorders in clinical trials and may serve as an avenue for the treatment of Parkinson's…”
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