Search Results - "Baltimore, D"

Our genome unveiled by Baltimore, David

“…The draft sequences of the human genome are remarkable achievements. They provide an outline of the information needed to create a human being and show, for…”
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Inhibiting HIV-1 Infection in Human T Cells by Lentiviral-Mediated Delivery of Small Interfering RNA against CCR5 by Qin, Xiao-Feng, An, Dong Sung, Irvin S. Y. Chen, Baltimore, David

“…Double-stranded RNAs ≈21 nucleotides long [small interfering RNA (siRNA)] are recognized as powerful reagents to reduce the expression of specific genes. To…”
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A path toward understanding neurodegeneration by Kosik, K. S., Sejnowski, T. J., Raichle, M. E., Ciechanover, A., Baltimore, D.

“…A focus on cell biology may accelerate progress in disease prevention and cures The specter of neurodegenerative disease, particularly Alzheimer's disease,…”
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The role of microRNA in nutritional control by Nolte‐’t Hoen, E. N. M., Van Rooij, E., Bushell, M., Zhang, C.‐Y., Dashwood, R. H., James, W. P. T., Harris, C., Baltimore, D.

“…MicroRNAs (miRNAs) are one of a growing class of noncoding RNAs that are involved in the regulation of a wide range of metabolic processes including cellular…”
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Retroviral Expression in Embryonic Stem Cells and Hematopoietic Stem Cells by Cherry, Sara R., Biniszkiewicz, D., van Parijs, L., Baltimore, D., Jaenisch, R.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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MicroRNA-125b Represses IRF4 to Induce Acute Myeloid Leukemia by Chaudhuri, A, So, A.Y, Sookram, R, Baltimore, D

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Anti-apoptotic effect of hyperglycemia can allow survival of potentially autoreactive T cells by Ramakrishnan, P, Kahn, D A, Baltimore, D

“…Thymocyte development is a tightly controlled multi-step process involving selective elimination of self-reactive and non-functional T cells by apoptosis. This…”
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Dual roles of ATM in the cellular response to radiation and in cell growth control by Xu, Y, Baltimore, D

“…The gene mutated in ataxia-telangiectasia (AT) patients, denoted ATM, encodes a putative protein or lipid kinase. To elucidate the functions of ATM, we…”
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Niclosamide, an anti-helminthic molecule, downregulates the retroviral oncoprotein Tax and pro-survival Bcl-2 proteins in HTLV-1-transformed T lymphocytes by Xiang, Di, Yuan, Yunsheng, Chen, Li, Liu, Xin, Belani, Chandra, Cheng, Hua

“…Adult T cell leukemia and lymphoma (ATL) is a highly aggressive form of hematological malignancy and is caused by chronic infection of human T cell leukemia…”
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Anti-apoptotic effect of hyperglycemia can allow survival of potentially autoreactive T cells by Ramakrishnan, P, Kahn, D A, Baltimore, D

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Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation by Baskaran, R, Wood, L. D, Whitaker, L. L, Canman, C. E, Morgan, S. E, Xu, Y, Barlow, C, Baltimore, D, Wynshaw-Boris, A, Kastan, M. B, Wang, J. Y. J

“…Ataxia telangiectasia (AT) is a rare human autosomal recessive disorder with pleiotropic phenotypes, including neuronal degeneration, immune dysfunction,…”
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Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment by Alcamo, E, Mizgerd, J P, Horwitz, B H, Bronson, R, Beg, A A, Scott, M, Doerschuk, C M, Hynes, R O, Baltimore, D

“…NF-kappaB binding sites are present in the promoter regions of many acute phase and inflammatory response genes, suggesting that NF-kappaB plays an important…”
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Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma by Xu, Y, Ashley, T, Brainerd, E E, Bronson, R T, Meyn, M S, Baltimore, D

“…ATM, the gene mutated in the inherited human disease ataxia-telangiectasia, is a member of a family of kinases involved in DNA metabolism and cell-cycle…”
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Proline‐rich (PxxP) motifs in HIV‐1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down‐regulation of CD4 by Saksela, K., Cheng, G., Baltimore, D.

“…Human immunodeficiency virus (HIV) and simian immunodeficiency virus Nef proteins contain a conserved motif with the minimal consensus (PxxP) site for Src…”
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Differences in urine cadmium associations with kidney outcomes based on serum creatinine and cystatin C by Weaver, Virginia M., Kim, Nam-Soo, Lee, Byung-Kook, Parsons, Patrick J., Spector, June, Fadrowski, Jeffrey, Jaar, Bernard G., Steuerwald, Amy J., Todd, Andrew C., Simon, David, Schwartz, Brian S.

“…Cadmium is a well-known nephrotoxicant; chronic exposure increases risk for chronic kidney disease. Recently, however, associations between urine cadmium and…”
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Rapid PD-L1 detection in tumors with PET using a highly specific peptide by Chatterjee, Samit, Lesniak, Wojciech G., Miller, Michelle S., Lisok, Ala, Sikorska, Emilia, Wharram, Bryan, Kumar, Dhiraj, Gabrielson, Matthew, Pomper, Martin G., Gabelli, Sandra B., Nimmagadda, Sridhar

“…Molecular imaging can report on the status of the tumor immune microenvironment and guide immunotherapeutic strategies to enhance the efficacy of immune…”
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Production of High-Titer Helper-Free Retroviruses by Transient Transfection by Pear, Warren S., Nolan, Garry P., Scott, Martin L., Baltimore, David

“…The generation of high-titer, helper-free retroviruses by transient transfection has been achieved by using the highly transfectable 293T cell line into which…”
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A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB by Baeuerle, P A, Baltimore, D

“…The NF-kappaB transcription factor was affinity-purified from deoxycholate (DOC)-treated cytosol of HeLa cells and shown to contain both a 50-kappaD…”
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Reduction of Caveolin and Caveolae in Oncogenically Transformed Cells by Koleske, Anthony J., Baltimore, David, Lisanti, Michael P.

“…Caveolae are flask-shaped non-clathrin-coated invaginations of the plasma membrane. In addition to the demonstrated roles for caveolae in potocytosis and…”
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Poliovirus RNA synthesis utilizes an RNP complex formed around the 5′‐end of viral RNA by Andino, R., Rieckhof, G.E., Achacoso, P.L., Baltimore, D.

“…The structure of a ribonucleoprotein complex formed at the 5′‐end of poliovirus RNA was investigated. This complex involves the first 90 nucleotides of…”
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