Search Results - "Balshaw, David"

Biomonitoring in the Era of the Exposome by Dennis, Kristine K, Marder, Elizabeth, Balshaw, David M, Cui, Yuxia, Lynes, Michael A, Patti, Gary J, Rappaport, Stephen M, Shaughnessy, Daniel T, Vrijheid, Martine, Barr, Dana Boyd

“…The term "exposome" was coined in 2005 to underscore the importance of the environment to human health and to bring research efforts in line with those on the…”
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The Importance of the Biological Impact of Exposure to the Concept of the Exposome by Dennis, Kristine K, Auerbach, Scott S, Balshaw, David M, Cui, Yuxia, Fallin, Margaret Daniele, Smith, Martyn T, Spira, Avrum, Sumner, Susan, Miller, Gary W

“…The term "exposome" was originally coined in 2005 and defined as the totality of exposures throughout the lifetime. The exposome provides an excellent…”
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Toward Greater Implementation of the Exposome Research Paradigm within Environmental Epidemiology by Stingone, Jeanette A, Buck Louis, Germaine M, Nakayama, Shoji F, Vermeulen, Roel C.H, Kwok, Richard K, Cui, Yuxia, Balshaw, David M, Teitelbaum, Susan L

“…Investigating a single environmental exposure in isolation does not reflect the actual human exposure circumstance nor does it capture the multifactorial…”
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Mitochondria, energetics, epigenetics, and cellular responses to stress by Shaughnessy, Daniel T, McAllister, Kimberly, Worth, Leroy, Haugen, Astrid C, Meyer, Joel N, Domann, Frederick E, Van Houten, Bennett, Mostoslavsky, Raul, Bultman, Scott J, Baccarelli, Andrea A, Begley, Thomas J, Sobol, Robert W, Hirschey, Matthew D, Ideker, Trey, Santos, Janine H, Copeland, William C, Tice, Raymond R, Balshaw, David M, Tyson, Frederick L

“…Cells respond to environmental stressors through several key pathways, including response to reactive oxygen species (ROS), nutrient and ATP sensing, DNA…”
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The Exposome: Embracing the Complexity for Discovery in Environmental Health by Cui, Yuxia, Balshaw, David M, Kwok, Richard K, Thompson, Claudia L, Collman, Gwen W, Birnbaum, Linda S

“…Environmental exposures are ubiquitous and play a fundamental role in the development of complex human diseases. The exposome, which is defined as the totality…”
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Informatics and Data Analytics to Support Exposome-Based Discovery for Public Health by Manrai, Arjun K, Cui, Yuxia, Bushel, Pierre R, Hall, Molly, Karakitsios, Spyros, Mattingly, Carolyn J, Ritchie, Marylyn, Schmitt, Charles, Sarigiannis, Denis A, Thomas, Duncan C, Wishart, David, Balshaw, David M, Patel, Chirag J

“…The complexity of the human exposome-the totality of environmental exposures encountered from birth to death-motivates systematic, high-throughput approaches…”
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The Children's Health Exposure Analysis Resource: enabling research into the environmental influences on children's health outcomes by Balshaw, David M, Collman, Gwen W, Gray, Kimberly A, Thompson, Claudia L

“…The Children's Health Exposure Analysis Resource (CHEAR) is a new infrastructure supported by the National Institute of Environmental Health Sciences to expand…”
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Expanding the Concept of Translational Research: Making a Place for Environmental Health Sciences by Pettibone, Kristianna G, Balshaw, David M, Dilworth, Caroline, Drew, Christina H, Hall, Janet E, Heacock, Michelle, Latoni, Alfonso R, McAllister, Kimberly A, O'Fallon, Liam R, Thompson, Claudia, Walker, Nigel J, Wolfe, Mary S, Wright, Demia S, Collman, Gwen W

“…The National Institute of Environmental Health Sciences (NIEHS) introduces a new translational research framework that builds upon previous biomedical models…”
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Integrating Multiscale Geospatial Environmental Data into Large Population Health Studies: Challenges and Opportunities by Cui, Yuxia, Eccles, Kristin M, Kwok, Richard K, Joubert, Bonnie R, Messier, Kyle P, Balshaw, David M

“…Quantifying the exposome is key to understanding how the environment impacts human health and disease. However, accurately, and cost-effectively quantifying…”
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Innovative Methods for Improving Measures of the Personal Environment by Balshaw, David M., PhD, Kwok, Richard K., PhD

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EXPOsOMICS: final policy workshop and stakeholder consultation by Turner, Michelle C, Vineis, Paolo, Seleiro, Eduardo, Dijmarescu, Michaela, Balshaw, David, Bertollini, Roberto, Chadeau-Hyam, Marc, Gant, Timothy, Gulliver, John, Jeong, Ayoung, Kyrtopoulos, Soterios, Martuzzi, Marco, Miller, Gary W, Nawrot, Timothy, Nieuwenhuijsen, Mark, Phillips, David H, Probst-Hensch, Nicole, Samet, Jonathan, Vermeulen, Roel, Vlaanderen, Jelle, Vrijheid, Martine, Wild, Christopher, Kogevinas, Manolis

“…The final meeting of the EXPOsOMICS project "Final Policy Workshop and Stakeholder Consultation" took place 28-29 March 2017 to present the main results of the…”
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Exposure Science in the 21st Century: Advancing the Science and Technology of Environmental Sensors through Cooperation and Collaboration across U.S. Federal Agencies by Hulla, Janis, Kilaru, Vasu, Doucette, Gregory, Balshaw, David, Watkins, Tim

“…The convergence of technological innovations in areas such as microelectronics, fabrication, the Internet-of-things (IoT), and smartphones, along with their…”
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Characterization of Recombinant Skeletal Muscle (Ser-2843) and Cardiac Muscle (Ser-2809) Ryanodine Receptor Phosphorylation Mutants by Stange, Mirko, Xu, Le, Balshaw, David, Yamaguchi, Naohiro, Meissner, Gerhard

“…Phosphorylation of the skeletal muscle (RyR1) and cardiac muscle (RyR2) ryanodine receptors has been reported to modulate channel activity. Abnormally high…”
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Gene-environment interactions within a precision environmental health framework by Motsinger-Reif, Alison A., Reif, David M., Akhtari, Farida S., House, John S., Campbell, C. Ryan, Messier, Kyle P., Fargo, David C., Bowen, Tiffany A., Nadadur, Srikanth S., Schmitt, Charles P., Pettibone, Kristianna G., Balshaw, David M., Lawler, Cindy P., Newton, Shelia A., Collman, Gwen W., Miller, Aubrey K., Merrick, B. Alex, Cui, Yuxia, Anchang, Benedict, Harmon, Quaker E., McAllister, Kimberly A., Woychik, Rick

“…Understanding the complex interplay of genetic and environmental factors in disease etiology and the role of gene-environment interactions (GEIs) across human…”
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ONE Nano: NIEHS's strategic initiative on the health and safety effects of engineered nanomaterials by Schug, Thaddeus T, Johnson, Anne F, Balshaw, David M, Garantziotis, Stavros, Walker, Nigel J, Weis, Christopher, Nadadur, Srikanth S, Birnbaum, Linda S

“…The past decade has seen tremendous expansion in the production and application of engineered nanomaterials (ENMs). The unique properties that make ENMs useful…”
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Interpreting Mobile and Handheld Air Sensor Readings in Relation to Air Quality Standards and Health Effect Reference Values: Tackling the Challenges by Woodall, George M, Hoover, Mark D, Williams, Ronald, Benedict, Kristen, Harper, Martin, Soo, Jhy-Charm, Jarabek, Annie M, Stewart, Michael J, Brown, James S, Hulla, Janis E, Caudill, Motria, Clements, Andrea L, Kaufman, Amanda, Parker, Alison J, Keating, Martha, Balshaw, David, Garrahan, Kevin, Burton, Laureen, Batka, Sheila, Limaye, Vijay S, Hakkinen, Pertti J, Thompson, Bob

“…The US Environmental Protection Agency (EPA) and other federal agencies face a number of challenges in interpreting and reconciling short-duration (seconds to…”
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Research Strategies for Safety Evaluation of Nanomaterials, Part III: Nanoscale Technologies for Assessing Risk and Improving Public Health by Balshaw, David M., Philbert, Martin, Suk, William A.

“…Risk assessment in the environmental health sciences focuses on understanding the nature of environmental exposures and the potential harm posed by those…”
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Luminal Loop of the Ryanodine Receptor: A Pore-Forming Segment? by Balshaw, David, Gao, Ling, Meissner, Gerhard

“…Many endogenous and exogenous effectors contribute to RyR1 regulation. RyR1 is partially actived by Ca2+ binding to high-affinity, Ca2+-specific sites and by…”
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Calmodulin Binding and Inhibition of Cardiac Muscle Calcium Release Channel (Ryanodine Receptor) by Balshaw, David M., Xu, Le, Yamaguchi, Naohiro, Pasek, Daniel A., Meissner, Gerhard

“…Metabolically 35S-labeled calmodulin (CaM) was used to determine the CaM binding properties of the cardiac ryanodine receptor (RyR2) and to identify potential…”
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Assessing the Exposome with External Measures: Commentary on the State of the Science and Research Recommendations by Turner, Michelle C, Nieuwenhuijsen, Mark, Anderson, Kim, Balshaw, David, Cui, Yuxia, Dunton, Genevieve, Hoppin, Jane A, Koutrakis, Petros, Jerrett, Michael

“…The exposome comprises all environmental exposures that a person experiences from conception throughout the life course. Here we review the state of the…”
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