Search Results - "Balsara, B."

Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions by Balsara, Binaifer R., Pei, Jianming, Mitsuuchi, Yasuhiro, Page, Robert, Klein-Szanto, Andres, Wang, Hao, Unger, Michael, Testa, Joseph R.

“…AKT is frequently activated in various cancers, but its involvement in lung tumor development and progression is not well established. We examined AKT activity…”
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Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins by BELINSKY, M. G, BAIN, L. J, BALSARA, B. B, TESTA, J. R, KRUH, G. D

“…Multidrug resistance-associated protein (MRP) and canalicular multispecific organic anion transporter (cMOAT) are transporter proteins that pump organic anions…”
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Chromosomal imbalances in human lung cancer: Lung cancer by BALSARA, Binaifer R, TESTA, Joseph R

“…A wealth of cytogenetic data has demonstrated that numerous somatic genetic changes are involved in the pathogenesis of human lung cancer. Despite the…”
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Detection of chromosomal aberrations by comparative genomic hybridization during transformation of human breast epithelial cells in vitro by BALOGH, G. A, RUSSO, I. H, BALSARA, B. R, RUSSO, J

“…Breast cancer is the most frequent malignancy in women. It is well recognized that tumorigenesis is a multistep process resulting from the accumulation of…”
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Comparative genomic hybridization analysis detects frequent, often high-level, overrepresentation of DNA sequences at 3q, 5p, 7p, and 8q in human non-small cell lung carcinomas by BALSARA, B. R, SONODA, G, DU MANOIR, S, SIEGFRIED, J. M, GABRIELSON, E, TESTA, J. R

“…Comparative genomic hybridization analysis was used to identify chromosomal imbalances in 20 non-small cell lung carcinoma (NSCLC) biopsies and cell lines. The…”
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Neurofibromatosis 2 and malignant mesothelioma by BASER, M. E, DE RIENZO, A, ALTOMARE, D, BALSARA, B. R, HEDRICK, N. M, GUTMANN, D. H, PITTS, L. H, JACKLER, R. K, TESTA, J. R

“…Mutations of the neurofibromatosis 2 (NF2) tumor suppressor gene cause the inherited disorder NF2 and are also common in malignant mesothelioma, which is not a…”
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Comparative genomic hybridization and loss of heterozygosity analyses identify a common region of deletion at 15q11.1-15 in human malignant mesothelioma by BALSARA, B. R, BELL, D. W, SONODA, G, DE RIENZO, A, DU MANOIR, S, JHANWAR, S. C, TESTA, J. R

“…Comparative genomic hybridization analysis was performed to identify chromosomal imbalances in 24 human malignant mesothelioma (MM) cell lines derived from…”
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Novel Human and Mouse Annexin A10 Are Linked to the Genome Duplications during Early Chordate Evolution by Morgan, Reginald O., Jenkins, Nancy A., Gilbert, Debra J., Copeland, Neal G., Balsara, Binaifer R., Testa, Joseph R., Fernandez, M.Pilar

“…We have identified and characterized a 12th subfamily of vertebrate annexins by systematic analysis of the primary structure, chromosomal mapping, and…”
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Genomic imbalances in human lung adenocarcinomas and squamous cell carcinomas by Pei, Jianming, Balsara, Binaifer R., Li, Wu, Litwin, Samuel, Gabrielson, Edward, Feder, Madelyn, Jen, Jin, Testa, Joseph R.

“…Comparative genomic hybridization analysis was performed on 67 non‐small‐cell lung cancers (NSCLCs), including 32 squamous cell carcinomas (SCCs) and 35…”
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Functional roles of chromosomes 11 and 17 in the transformation of human breast epithelial cells in vitro by Yang, X, Tahin, Q, Hu, Y F, Russo, I H, Balsara, B R, Mihaila, D, Slater, C, Barrett, J C, Russo, J

“…Genomic alterations in primary breast cancer play a role in the initiation and progression of the disease. We have analyzed the molecular events involved in…”
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893P Clinico-genetic profiling of HRAS mutant head and neck squamous cell carcinoma (HNSCC) by Le, X., Marcelo, K., Coleman, N., Hopkins, J., Balsara, B., Leoni, M., Spelman, A.R., Hong, D.S., Albacker, L.A., Gillison, M.

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LBA47 A phase II study evaluating tipifarnib in mHRAS, recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) (AIM-HN study) by Ho, A.L., Adkins, D.R., Hanna, G.J., Bruce, J., Ahn, M-J., Iglesias Docampo, L., Kang, H., Wong, D.J., Psyrri, A., Gillison, M., Braña, I., Liu, Y.C., Hsieh, C-Y., Hong, M.H., Zhang, Z., Balsara, B., Saunders, A., Gasco Hernandez, A., Dale, S., Haddad, R.

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Human hepatocellular carcinoma is characterized by a highly consistent pattern of genomic imbalances, including frequent loss of 16q23.1-24.1 by Balsara, Binaifer R., Pei, Jianming, De Rienzo, Assunta, Simon, Daniela, Tosolini, Alessandra, Lu, You Yong, Shen, Fu-Min, Fan, Xianglin, Lin, Wen-Yao, Buetow, Kenneth H., London, W. Thomas, Testa, Joseph R.

“…Comparative genomic hybridization (CGH) analysis was used to identify chromosomal imbalances in 52 human primary hepatocellular carcinomas (HCCs). The most…”
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Loss of heterozygosity analysis defines a 3-cM region of 15q commonly deleted in human malignant mesothelioma by De Rienzo, A, Balsara, B R, Apostolou, S, Jhanwar, S C, Testa, J R

“…Previous comparative genomic hybridization and allelic loss analyses demonstrated frequent deletions from 15q11.1-15 in malignant mesothelioma. Recurrent…”
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Cloning and Chromosomal Localization of a Gene Encoding a Novel Serine/Threonine Kinase Belonging to the Subfamily of Testis-Specific Kinases by Visconti, Pablo E, Hao, Zhonglin, Purdon, Marie A, Stein, Paula, Balsara, Binaifer R, Testa, Joseph R, Herr, John C, Moss, Stuart B, Kopf, Gregory S

“…Using reverse transcription–polymerase chain reaction (RT-PCR) with degenerate oligonucleotides corresponding to two highly conserved motifs within the protein…”
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Cytogenetic studies on a patient with prepubertal breast cancer : a case report by BALSARA, B. R, VARUGHESE, T, BHAT, A. V, RAO, R. S, BHISEY, A. N

“…Cytogenetic studies were carried in a 10 year old girl with prepubertal breast cancer for assessing inherited genetic susceptibility to chromosome breakage…”
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DNA analysis of breast cancer by flow cytometry & correlation with other prognostic parameters by Redkar, A A, Balsara, B R, Bhisey, A N, Sampat, M B, Mittra, I

“…Flow cytometric estimation of DNA content (ploidy and S-phase fraction--SpF) was done on breast cancer tissues from 171 patients. Twenty eight per cent of the…”
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T-lymphoid blast crisis in chronic myeloid leukemia by Advani, S H, Malhotra, H, Kadam, P R, Iyer, R S, Nanjangud, G, Balsara, B, Saikia, T, Gopal, R, Nair, C N

“…Chronic myeloid leukemia (CML) is considered to be a pleuripotential stem cell disorder with the capacity to differentiate into myeloid, erythroid,…”
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Comparative genomic hybridization of human breast epithelial cells transformed by estrogen and its metabolites by Fernandez, Sandra V, Russo, Irma H, Lareef, Mohamed, Balsara, Binaifer, Russo, Jose

“…The elevated incidence of breast cancer in women has been associated with prolonged exposure to high levels of estrogens. Our laboratory has demonstrated that…”
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Flow cytometric DNA analysis of squamous cell carcinomas of the oral cavity: correlation with clinical and histopathological features by Balsara, B R, Borges, A M, Pradhan, S A, Rajpal, R M, Bhisey, A N

“…DNA content was measured in 68 squamous cell carcinomas (SCC) of the oral cavity by flow cytometry. Samples fixed in 95% alcohol and disaggregated with 0.5%…”
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