Search Results - "Balsano, Rita"
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Pancreatic Ductal Adenocarcinoma and Immune Checkpoint Inhibitors: The Gray Curtain of Immunotherapy and Spikes of Lights
Published in Current oncology (Toronto) (30-03-2023)“…Pancreatic ductal adenocarcinoma (PDAC) is a dismal disease with a poor 5-year overall survival rate (~10%). The revolution of immunotherapy in clinical…”
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Small Bowel Adenocarcinoma: From Molecular Insights to Clinical Management
Published in Current oncology (Toronto) (17-02-2022)“…Small bowel adenocarcinoma (SBA) is a rare malignancy, with a rising incidence in recent decades, and accounts for roughly 40% of all cancers of the small…”
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Biological Hallmarks and New Therapeutic Approaches for the Treatment of PDAC
Published in Life (Basel, Switzerland) (18-08-2021)“…Pancreatic Ductal Adenocarcinoma (PDAC) is one of the deadliest solid tumors and is estimated to become a leading cause of cancer-related death in coming…”
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Potential Role of Exosomes in the Chemoresistance to Gemcitabine and Nab-Paclitaxel in Pancreatic Cancer
Published in Diagnostics (Basel) (23-01-2022)“…In recent years, a growing number of studies have evaluated the role of exosomes in pancreatic ductal adenocarcinoma cancer (PDAC) demonstrating their…”
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The Growing Skyline of Advanced Hepatocellular Carcinoma Treatment: A Review
Published in Pharmaceuticals (Basel, Switzerland) (08-01-2021)“…Hepatocellular carcinoma (HCC) is the main type of liver cancer. In the majority of cases, HCC is diagnosed at the advanced stage, leading to poor prognosis…”
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Transforming Growth Factor-Beta Signaling in Cancer-Induced Cachexia: From Molecular Pathways to the Clinics
Published in Cells (Basel, Switzerland) (28-08-2022)“…Cachexia is a metabolic syndrome consisting of massive loss of muscle mass and function that has a severe impact on the quality of life and survival of cancer…”
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It Takes Two to Tango: Potential Prognostic Impact of Circulating TGF-Beta and PD-L1 in Pancreatic Cancer
Published in Life (Basel, Switzerland) (26-06-2022)“…Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly devastating disease with rising incidence and poor prognosis. The lack of reliable prognostic…”
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The implication of liquid biopsies to predict chemoresistance in pancreatic cancer
Published in Cancer drug resistance (01-01-2021)“…Pancreatic cancer is one of the most aggressive diseases among solid tumors. Most patients are diagnosed with advanced or metastatic disease and are…”
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State of the Art for Metastatic Pancreatic Cancer Treatment: Where Are We Now?
Published in Anticancer research (01-07-2019)“…The prognosis of metastatic pancreatic cancer remains poor despite the recent progress on modern chemotherapeutic regimens, such as FOLFIRINOX, gemcitabine and…”
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SAT-523 Intrahepatic cholangiocarcinoma: characteristics and outcomes of patients with or without underlying liver disease
Published in Journal of hepatology (01-06-2024)Get full text
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Olaparib as a single agent treatment in pre-treated metastatic pancreatic cancer patient harboring BRCA2 mutation: What could we expect?
Published in Tumori (01-12-2022)“…Background: Despite ongoing developments, pancreatic cancer remains one of the most difficult tumors to treat. Even the most effective chemotherapy regimens,…”
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THU-474-YI Immunotherapy in cholangiocarcinoma: understanding the immune landscape reveals treatment response
Published in Journal of hepatology (01-06-2024)Get full text
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The role of the microbiome in drug resistance in gastrointestinal cancers
Published in Expert review of anticancer therapy (01-02-2021)“…Introduction: The microbiota is recognized for its impact on both human health and disease. The human microbiota is made up of trillions of cells, including…”
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Multicenter phase I/II trial of gemcitabine, oxaliplatin and nab-paclitaxel as first-line treatment for patients with advanced biliary tract cancer
Published in European journal of cancer (1990) (01-08-2024)“…The prognosis of patients with advanced biliary tract cancer (BTC) is still poor, and new strategies improving patients’ outcome are needed. In our trial we…”
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“Depart from evil, and do good”: Turning Axl from uncontrolled tumorigenic gene to biomarker for early detection of pancreatic cancer
Published in Critical reviews in oncology/hematology (01-05-2022)“…Attempts to achieve early diagnosis are crucial to improve the outcome of patients with pancreatic ductal adenocarcinoma (PDAC). Here we present a critical…”
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Durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer: A large real-life worldwide population
Published in European journal of cancer (1990) (01-09-2024)“…The TOPAZ-1 phase III trial showed a survival benefit with durvalumab plus gemcitabine and cisplatin in patients with advanced biliary tract cancer (BTC). To…”
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Efficacy of cisplatin-gemcitabine-durvalumab in patients with advanced biliary tract cancer experiencing early vs late disease relapse after surgery: a large real-life worldwide population
Published in The oncologist (Dayton, Ohio) (19-10-2024)“…In the TOPAZ-1, patients with biliary tract cancers (BTC) and recurrence within 6 months after surgery were excluded, even if this event is frequently observed…”
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Safety and Efficacy of Atezolizumab and Bevacizumab Combination as a First Line Treatment of Advanced Hepatocellular Carcinoma
Published in Journal of hepatocellular carcinoma (01-01-2023)“…Hepatocellular carcinoma (HCC) is one of the most common leading causes of cancer death worldwide. As most patients are diagnosed with advanced disease,…”
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