Search Results - "Balogh, Dora"

SGLT2 inhibitor dapagliflozin prevents atherosclerotic and cardiac complications in experimental type 1 diabetes by Hodrea, Judit, Saeed, Adar, Molnar, Agnes, Fintha, Attila, Barczi, Adrienn, Wagner, Laszlo J, Szabo, Attila J, Fekete, Andrea, Balogh, Dora B

“…Cardiovascular disease (CVD) is two to five times more prevalent in diabetic patients and is the leading cause of death. Therefore, identification of novel…”
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FEMaLe: The use of machine learning for early diagnosis of endometriosis based on patient self-reported data-Study protocol of a multicenter trial by Balogh, Dora B, Hudelist, Gernot, Bļizņuks, Dmitrijs, Raghothama, Jayanth, Becker, Christian M, Horace, Roman, Krentel, Harald, Horne, Andrew W, Bourdel, Nicolas, Marki, Gabriella, Tomassetti, Carla, Kirk, Ulrik Bak, Acs, Nandor, Bokor, Attila

“…Endometriosis is a chronic disease that affects up to 190 million women and those assigned female at birth and remains unresolved mainly in terms of etiology…”
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Cryo-EM structure of the ClpXP protein degradation machinery by Gatsogiannis, Christos, Balogh, Dora, Merino, Felipe, Sieber, Stephan A., Raunser, Stefan

“…The ClpXP machinery is a two-component protease complex that performs targeted protein degradation in bacteria and mitochondria. The complex consists of the…”
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10-LB: Activation of Sigma-1 Receptor as a Novel Therapeutic Target in Diabetic Kidney Disease by BALOGH, DORA B., LENART, LILLA, HOSSZU, ADAM, SAEED, ADAR, HODREA, JUDIT, TOTH, AKOS R., SZABO, ATTILA J., FEKETE, ANDREA

“…Introduction and aims: Diabetic kidney disease (DKD) is a major health concern among diabetic patients. Current therapies cannot halt the progression of renal…”
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Reduced O -GlcNAcylation and tubular hypoxia contribute to the antifibrotic effect of SGLT2 inhibitor dapagliflozin in the diabetic kidney by Hodrea, Judit, Balogh, Dora B, Hosszu, Adam, Lenart, Lilla, Besztercei, Balazs, Koszegi, Sandor, Sparding, Nadja, Genovese, Federica, Wagner, Laszlo J, Szabo, Attila J, Fekete, Andrea

“…Diabetic kidney disease is a worldwide epidemic, and therapies are incomplete. Clinical data suggest that improved renal outcomes by Na -glucose cotransporter…”
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Analysis of Telomerase by the Telomeric Hemin/G-Quadruplex-Controlled Aggregation of Au Nanoparticles in the Presence of Cysteine by Sharon, Etery, Golub, Eyal, Niazov-Elkan, Angelica, Balogh, Dora, Willner, Itamar

“…Telomeres are guanosine-rich nucleic-acid chains that fold, in the presence of K+ ions and hemin, into the telomeric hemin/G-quadruplex structure, exhibiting…”
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Cardioprotective and Antifibrotic Effects of Low-Dose Renin-Angiotensin-Aldosterone System Inhibitors in Type 1 Diabetic Rat Model by Balogh, Dora B, Molnar, Agnes, Degi, Arianna, Toth, Akos, Lenart, Lilla, Saeed, Adar, Barczi, Adrienn, Szabo, Attila J, Wagner, Laszlo J, Reusz, Gyorgy, Fekete, Andrea

“…Diabetic cardiovascular complications are associated with up to 50% mortality, and current therapies are not effective enough. Renin-angiotensin-aldosterone…”
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Antidepressant effect in diabetes-associated depression: A novel potential of RAAS inhibition by Balogh, Dora B., Molnar, Agnes, Hosszu, Adam, Lakat, Tamas, Hodrea, Judit, Szabo, Attila J., Lenart, Lilla, Fekete, Andrea

“…Summary of the antidepressant-like mechanism of RAAS-acting drugs. Systemic and local brain renin-angiotensin-aldosterone system (RAAS) are overactivated in…”
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σ1-Receptor Agonism Protects against Renal Ischemia-Reperfusion Injury by Hosszu, Adam, Antal, Zsuzsanna, Lenart, Lilla, Hodrea, Judit, Koszegi, Sandor, Balogh, Dora B, Banki, Nora F, Wagner, Laszlo, Denes, Adam, Hamar, Peter, Degrell, Peter, Vannay, Adam, Szabo, Attila J, Fekete, Andrea

“…Mechanisms of renal ischemia-reperfusion injury remain unresolved, and effective therapies are lacking. We previously showed that dehydroepiandrosterone…”
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Tailored Peptide Phenyl Esters Block ClpXP Proteolysis by an Unusual Breakdown into a Heptamer–Hexamer Assembly by Lakemeyer, Markus, Bertosin, Eva, Möller, Friederike, Balogh, Dóra, Strasser, Ralf, Dietz, Hendrik, Sieber, Stephan A.

“…The proteolytic complex ClpXP is fundamental to bacterial homeostasis and pathogenesis. Because of its conformational flexibility, the development of potent…”
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Selective Activation of Human Caseinolytic Protease P (ClpP) by Stahl, Matthias, Korotkov, Vadim S., Balogh, Dóra, Kick, Leonhard M., Gersch, Malte, Pahl, Axel, Kielkowski, Pavel, Richter, Klaus, Schneider, Sabine, Sieber, Stephan A.

“…Caseinolytic protease P (ClpP) is the proteolytic component of the ClpXP protein degradation complex. Eukaryotic ClpP was recently found to act within the…”
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Novel therapeutic potential of angiotensin receptor 1 blockade in a rat model of diabetes-associated depression parallels altered BDNF signalling by Lenart, Lilla, Balogh, Dora B., Lenart, Nikolett, Barczi, Adrienn, Hosszu, Adam, Farkas, Tamas, Hodrea, Judit, Szabo, Attila J., Szigeti, Krisztian, Denes, Adam, Fekete, Andrea

“…Aims/hypothesis Diabetes is a worldwide epidemic linked with diverse diseases of the nervous system, including depression. A few studies suggested a connection…”
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Insights into ClpXP proteolysis: heterooligomerization and partial deactivation enhance chaperone affinity and substrate turnover in Listeria monocytogenes by Balogh, Dóra, Dahmen, Maria, Stahl, Matthias, Poreba, Marcin, Gersch, Malte, Drag, Marcin, Sieber, Stephan A

“…Caseinolytic proteases (ClpP) are important for recognition and controlled degradation of damaged proteins. While the majority of bacterial organisms utilize…”
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25-LB: SGLT2 Inhibitors Are Renoprotective via Mitigation of Tubular Hypoxia and Protein O-GlcNAcylation by BALOGH, DORA B., HODREA, JUDIT, LENART, LILLA, HOSSZU, ADAM, MEZEI, CSENGE, WAGNER, LASZLO, SZABO, ATTILA J., FEKETE, ANDREA

“…Tubular hypoxia has a major pathogenic role in diabetic kidney disease (DKD). Hypoxia is in strong association with elevated glucose reabsorption and increased…”
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Listeria monocytogenes utilizes the ClpP1/2 proteolytic machinery for fine-tuned substrate degradation at elevated temperatures by Balogh, Dóra, Eckel, Konstantin, Fetzer, Christian, Sieber, Stephan A.

“…Listeria monocytogenes exhibits two ClpP isoforms (ClpP1/ClpP2) which assemble into a heterooligomeric complex with enhanced proteolytic activity. Herein, we…”
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An Overview of the Cardioprotective Effects of Novel Antidiabetic Classes: Focus on Inflammation, Oxidative Stress, and Fibrosis by Balogh, Dora Bianka, Wagner, Laszlo Jozsef, Fekete, Andrea

“…Metabolic diseases, particularly diabetes mellitus (DM), are significant global public health concerns. Despite the widespread use of standard-of-care…”
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Non-covalently embedded oxytocin in alkanethiol monolayer as Zn2+ selective biosensor by Attia, Jessica, Nir, Sivan, Mervinetsky, Evgeniy, Balogh, Dora, Gitlin-Domagalska, Agata, Alshanski, Israel, Reches, Meital, Hurevich, Mattan, Yitzchaik, Shlomo

“…Peptides are commonly used as biosensors for analytes such as metal ions as they have natural binding preferences. In our previous peptide-based impedimetric…”
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The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats by Lenart, Lilla, Hodrea, Judit, Hosszu, Adam, Koszegi, Sandor, Zelena, Dora, Balogh, Dora, Szkibinszkij, Edgar, Veres-Szekely, Apor, Wagner, Laszlo, Vannay, Adam, Szabo, Attila J., Fekete, Andrea

“…Rationale Depression is highly prevalent in diabetes (DM). Brain-derived neurotrophic factor (BDNF) which is mainly regulated by the endoplasmic reticulum…”
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RAAS inhibitors directly reduce diabetes‐induced renal fibrosis via growth factor inhibition by Koszegi, Sandor, Molnar, Agnes, Lenart, Lilla, Hodrea, Judit, Balogh, Dora Bianka, Lakat, Tamas, Szkibinszkij, Edgar, Hosszu, Adam, Sparding, Nadja, Genovese, Federica, Wagner, Laszlo, Vannay, Adam, Szabo, Attila J, Fekete, Andrea

“…Key points Increased activation of the renin‐angiotensin‐aldosterone system (RAAS) and elevated growth factor production are of crucial importance in the…”
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Enzyme-catalyzed kinetic resolution of N-Boc-trans-3-hydroxy-4-phenylpyrrolidine by Faigl Ferenc, Kovács Ervin, Balogh Dóra, Holczbauer Tamás, Czugler Mátyás, Simándi Béla

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