Search Results - "Balog, Julia"
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The surgical intelligent knife distinguishes normal, borderline and malignant gynaecological tissues using rapid evaporative ionisation mass spectrometry (REIMS)
Published in British journal of cancer (01-05-2018)“…Background Survival from ovarian cancer (OC) is improved with surgery, but surgery can be complex and tumour identification, especially for borderline ovarian…”
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In Situ, Real-Time Identification of Biological Tissues by Ultraviolet and Infrared Laser Desorption Ionization Mass Spectrometry
Published in Analytical chemistry (Washington) (01-03-2011)“…Laser desorption ionization-mass spectrometric (LDI-MS) analysis of vital biological tissues and native, ex vivo tissue specimens is described. It was found…”
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Real-Time Molecular Diagnosis of Tumors Using Water-Assisted Laser Desorption/Ionization Mass Spectrometry Technology
Published in Cancer cell (12-11-2018)“…Histopathological diagnosis of biopsy samples and margin assessment of surgical specimens are challenging aspects in sarcoma. Using dog patient tissues, we…”
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Rapid evaporative ionisation mass spectrometry of electrosurgical vapours for the identification of breast pathology: towards an intelligent knife for breast cancer surgery
Published in Breast cancer research : BCR (23-05-2017)“…Re-operation for positive resection margins following breast-conserving surgery occurs frequently (average = 20-25%), is cost-inefficient, and leads to…”
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The intelligent knife (iKnife) and its intraoperative diagnostic advantage for the treatment of cervical disease
Published in Proceedings of the National Academy of Sciences - PNAS (31-03-2020)“…Clearance of surgical margins in cervical cancer prevents the need for adjuvant chemoradiation and allows fertility preservation. In this study, we determined…”
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In Vivo Endoscopic Tissue Identification by Rapid Evaporative Ionization Mass Spectrometry (REIMS)
Published in Angewandte Chemie International Edition (14-09-2015)“…Gastrointestinal cancers are a leading cause of mortality, accounting for 23 % of cancer‐related deaths worldwide. In order to improve outcomes from these…”
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Characterisation of Canine and Feline Breast Tumours, Their Metastases, and Corresponding Primary Cell Lines Using LA-REIMS and DESI-MS Imaging
Published in International journal of molecular sciences (15-07-2024)“…Breast cancer, a complex disease with a significant prevalence to form metastases, necessitates novel therapeutic strategies to improve treatment outcomes…”
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A novel methodology for in vivo endoscopic phenotyping of colorectal cancer based on real-time analysis of the mucosal lipidome: a prospective observational study of the iKnife
Published in Surgical endoscopy (01-03-2017)“…Background This pilot study assessed the diagnostic accuracy of rapid evaporative ionization mass spectrometry (REIMS) in colorectal cancer (CRC) and colonic…”
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High-Throughput Drug Stability Assessment via Biomimetic Metalloporphyrin-Catalyzed Reactions Using Laser-Assisted Rapid Evaporative Ionization Mass Spectrometry (LA-REIMS)
Published in Pharmaceutics (27-09-2024)“…Building extensive drug candidate libraries as early in the development pipeline as possible, with high-throughput in vitro absorption, distribution,…”
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Identification of Biological Tissues by Rapid Evaporative Ionization Mass Spectrometry
Published in Analytical chemistry (Washington) (01-09-2010)“…The newly developed rapid evaporative ionization mass spectrometry (REIMS) provides the possibility of in vivo, in situ mass spectrometric tissue analysis. The…”
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Testing of rapid evaporative mass spectrometry for histological tissue classification and molecular diagnostics in a multi-site study
Published in British journal of cancer (02-11-2024)“…Background While REIMS technology has successfully been demonstrated for the histological identification of ex-vivo breast tumor tissues, questions regarding…”
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Analysis of colorectal adenocarcinoma tissue by desorption electrospray ionization mass spectrometric imaging
Published in Analytical and bioanalytical chemistry (01-06-2012)“…Negative ion desorption electrospray ionization (DESI) was used for the analysis of an ex vivo tissue sample set comprising primary colorectal adenocarcinoma…”
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Harmonization of Rapid Evaporative Ionization Mass Spectrometry Workflows across Four Sites and Testing Using Reference Material and Local Food-Grade Meats
Published in Metabolites (17-11-2022)“…Rapid evaporative ionization mass spectrometry (REIMS) is a direct tissue metabolic profiling technique used to accurately classify tissues using pre-built…”
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XMS: Cross-Platform Normalization Method for Multimodal Mass Spectrometric Tissue Profiling
Published in Journal of the American Society for Mass Spectrometry (01-01-2015)“…Here we present a proof of concept cross-platform normalization approach to convert raw mass spectra acquired by distinct desorption ionization methods and/or…”
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Estrogen induces estrogen receptor alpha-dependent cAMP response element-binding protein phosphorylation via mitogen activated protein kinase pathway in basal forebrain cholinergic neurons in vivo
Published in The Journal of neuroscience (12-04-2006)“…In addition to classical genomic mechanisms, estrogen also exerts nonclassical effects via a signal transduction system on neurons. To study whether estrogen…”
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Electrospray Post-Ionization Mass Spectrometry of Electrosurgical Aerosols
Published in Journal of the American Society for Mass Spectrometry (01-11-2011)“…The feasibility of electrospray (ES) ionization of aerosols generated by electrosurgical disintegration methods was investigated. Although electrosurgery…”
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Intraoperative tissue identification using rapid evaporative ionization mass spectrometry
Published in Science translational medicine (17-07-2013)“…Rapid evaporative ionization mass spectrometry (REIMS) is an emerging technique that allows near-real-time characterization of human tissue in vivo by analysis…”
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In Vivo, In Situ Tissue Analysis Using Rapid Evaporative Ionization Mass Spectrometry
Published in Angewandte Chemie (International ed.) (19-10-2009)“…Beam me up: A novel mass spectrometric ionization technique based on rapid evaporation of biological tissues (see picture) can be used to analyze vital tissues…”
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Real Time Analysis of Brain Tissue by Direct Combination of Ultrasonic Surgical Aspiration and Sonic Spray Mass Spectrometry
Published in Analytical chemistry (Washington) (15-10-2011)“…Direct combination of cavitron ultrasonic surgical aspirator (CUSA) and sonic spray ionization mass spectrometry is presented. A commercially available…”
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Matrix Assisted Rapid Evaporative Ionization Mass Spectrometry
Published in Analytical chemistry (Washington) (06-08-2019)“…Rapid evaporative ionization mass spectrometry (REIMS) is a highly versatile technique allowing the sampling of a range of biological solid or liquid samples…”
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