Search Results - "Balmforth, A.J."
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Effect of a common X-linked angiotensin II type 2-receptor gene polymorphism (−1332 G/A) on the occurrence of premature myocardial infarction and stenotic atherosclerosis requiring revascularization
Published in Atherosclerosis (01-11-2007)“…Abstract Objectives To assess the association of the angiotensin II type 2 (AT2 ) receptor (−1332 G/A) gene polymorphism with premature coronary artery disease…”
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Neprilysin, obesity and the metabolic syndrome
Published in International Journal of Obesity (01-08-2011)“…Objective: Neprilysin (NEP), a zinc metalloendopeptidase, has a role in blood pressure control and lipid metabolism. The present study tested the hypothesis…”
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The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy
Published in The pharmacogenomics journal (01-02-2010)“…Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are well established in the treatment of hypercholesterolaemia and the prevention of…”
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Functional expression of glucose-dependent insulinotropic polypeptide receptors is coupled to differentiation in a human adipocyte model
Published in International Journal of Obesity (01-11-2008)“…Objective: To establish that human adipocytes express functional glucose-dependent insulinotropic peptide (GIP) receptors and in particular the regulation of…”
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An evaluation of the beta-1 adrenergic receptor Arg389Gly polymorphism in individuals at risk of coronary events. A WOSCOPS substudy
Published in European heart journal (01-07-2002)“…Aims The Glycine389 variant of the beta-1 adrenergic receptor generates markedly less cAMP when stimulated in vitro than the more prevalent Arginine389 variant…”
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The effect of the angiotensin II (AT 1A) receptor stably transfected into human neuroblastoma SH-SY5Y cells on noradrenaline release and changes in intracellular calcium
Published in Neuroscience letters (20-10-1995)“…A stable cell line expressing the angiotensin II (AII) receptor has been obtained by transfecting the human neuroblastoma SH-SY5Y with the plasmid pCEP4…”
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Isolation and characterization of glyoxylate dehydrogenase from the fungus Sclerotium rolfsii
Published in Biochemical journal (15-02-1984)“…Glyoxylate dehydrogenase (glyoxylate:NAD+ oxidoreductase) was purified 600-fold in three steps from crude extracts of the fungus Sclerotium rolfsii (Corticium…”
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