Search Results - "Ballock, R. Tracy"

Sox9 Directs Hypertrophic Maturation and Blocks Osteoblast Differentiation of Growth Plate Chondrocytes by Dy, Peter, Wang, Weihuan, Bhattaram, Pallavi, Wang, Qiuqing, Wang, Lai, Ballock, R. Tracy, Lefebvre, Véronique

“…The transcription factor Sox9 is necessary for early chondrogenesis, but its subsequent roles in the cartilage growth plate, a highly specialized structure…”
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Thyroid hormone‐mediated growth and differentiation of growth plate chondrocytes involves IGF‐1 modulation of β‐catenin signaling by Wang, Lai, Shao, Yvonne Y, Ballock, R Tracy

“…Thyroid hormone regulates terminal differentiation of growth plate chondrocytes in part through modulation of the Wnt/β‐catenin signaling pathway. Insulin‐like…”
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Primary cilia modulate Ihh signal transduction in response to hydrostatic loading of growth plate chondrocytes by Shao, Yvonne Y, Wang, Lai, Welter, Jean F, Ballock, R. Tracy

“…Abstract Indian hedgehog (Ihh) is a key component of the regulatory apparatus governing chondrocyte proliferation and differentiation in the growth plate…”
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Activation of Wnt Planar cell polarity (PCP) signaling promotes growth plate column formation in vitro by Randall, Rachel M., Shao, Yvonne Y., Wang, Lai, Ballock, R. Tracy

“…Disrupting the Wnt Planar Cell Polarity (PCP) signaling pathway in vivo results in loss of columnar growth plate architecture, but it is unknown whether…”
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The Biology of the Growth Plate by Ballock, R Tracy, OʼKeefe, Regis J

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Leptin synergizes with thyroid hormone signaling in promoting growth plate chondrocyte proliferation and terminal differentiation in vitro by Wang, Lai, Shao, Yvonne Y, Ballock, R. Tracy

“…Abstract Leptin and thyroid hormone are two hormones that regulate energy balance through central signaling mechanisms. Recent studies in leptin-deficient…”
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Carboxypeptidase Z (CPZ) Links Thyroid Hormone and Wnt Signaling Pathways in Growth Plate Chondrocytes by Wang, Lai, Shao, Yvonne Y, Ballock, R Tracy

“…Carboxypeptidase Z (CPZ) removes carboxyl‐terminal basic amino acid residues, particularly arginine residues, from proteins. CPZ contains a cysteine‐rich…”
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Osteonecrosis of the Femoral Head in an Adolescent on Long-Term Inhalational Corticosteroids by Egger, Anthony C., Ballock, R. Tracy

“…A relationship between the development of osteonecrosis of the femoral head and systemic corticosteroids has been well established in the literature,…”
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Thyroid hormone and the growth plate by Shao, Yvonne Y, Wang, Lai, Ballock, R Tracy

“…Thyroid hormone was first identified as a potent regulator of skeletal maturation at the growth plate more than forty years ago. Since that time, many in vitro…”
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Physiology and pathophysiology of the growth plate by Ballock, R. Tracy, O'Keefe, Regis J.

“…Longitudinal growth of the skeleton is a result of endochondral ossification that occurs at the growth plate. Through a sequential process of cell…”
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Leptin Antagonizes Peroxisome Proliferator-Activated Receptor-γ Signaling in Growth Plate Chondrocytes by Wang, Lai, Shao, Yvonne Y., Ballock, R. Tracy

“…Leptin is an obesity-associated cytokine-like hormone encoded by the ob gene. Recent studies reveal that leptin promotes proliferation and differentiation of…”
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Analysis of gene expression in mineralized skeletal tissues by laser capture microdissection and RT-PCR by Shao, Yvonne Y, Wang, Lai, Hicks, David G, Ballock, R Tracy

“…The analysis of gene expression by growth plate chondrocytes in vivo has been hampered by the inherent difficulty in performing in situ hybridization on…”
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Thyroid Hormone Interacts With the Wnt/β‐Catenin Signaling Pathway in the Terminal Differentiation of Growth Plate Chondrocytes by Wang, Lai, Shao, Yvonne Y, Ballock, R Tracy

“…Thyroid hormone activates Wnt‐4 expression and Wnt/β‐catenin signaling in rat growth plate chondrocytes. Wnt antagonists Frzb/sFRP3 and Dkk1 inhibit T3‐induced…”
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Expression and activation of peroxisome proliferator-activated receptors in growth plate chondrocytes by Shao, Yvonne Y., Wang, Lai, Hicks, David G., Tarr, Shannon, Ballock, R. Tracy

“…Peroxisome proliferator-activated receptor γ (PPAR-γ) is a nuclear hormone receptor that is involved in a wide range of cellular processes. Although it is…”
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Peroxisome Proliferator-Activated Receptor-γ Promotes Adipogenic Changes in Growth Plate Chondrocytes In Vitro by Wang, Lai, Shao, Yvonne Y, Ballock, R Tracy

“…Chondrocytes and adipocytes are two differentiated cell types which are both derived from mesenchymal cells. The purpose of this study was to investigate…”
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Expression and Activity of the CDK Inhibitor p57Kip2 in Chondrocytes Undergoing Hypertrophic Differentiation by Stewart, Matthew C, Kadlcek, Renata M, Robbins, Paul D, Macleod, James N, Ballock, R Tracy

“…Growth plates ofp57‐null mice exhibit several abnormalities, including loss of collagen type X (CollX) expression. The phenotypic consequences of p57…”
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Cost analysis of adolescent idiopathic scoliosis surgery: early discharge decreases hospital costs much less than intraoperative variables under the control of the surgeon by Raudenbush, Brandon L., Gurd, David P., Goodwin, Ryan C., Kuivila, Thomas E., Ballock, R. Tracy

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Closed reduction for treatment of developmental dysplasia of the hip in children by Murray, Trevor, Cooperman, Daniel R, Thompson, George H, Ballock, R Tracy

“…Although many studies have analyzed the success rates of closed reduction and spica casting for the treatment of developmental dysplasia of the hip (DDH) in…”
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Salter-Harris Type II Fractures of the Capital Femoral Epiphysis by Thompson, George H, Bachner, Evan J, Ballock, R Tracy

“…Salter-Harris type II fractures of the capital femoral epiphysis have not been previously documented. The authors have treated three patients who sustained…”
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Expression of Cyclin-Dependent Kinase Inhibitors in Epiphyseal Chondrocytes Induced to Terminally Differentiate with Thyroid Hormone by Ballock, R. Tracy, Zhou, Xiaolan, Mink, Lynn M, Chen, Daniel H. C, Mita, Barry C, Stewart, Matthew C

“…A growing body of evidence suggests that systemic hormones and peptide growth factors may exert their effects on cell growth and differentiation in part…”
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