Search Results - "Ballinger, J"
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Generality of toxins in defensive symbiosis: Ribosome-inactivating proteins and defense against parasitic wasps in Drosophila
Published in PLoS pathogens (06-07-2017)“…While it has become increasingly clear that multicellular organisms often harbor microbial symbionts that protect their hosts against natural enemies, the…”
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Subtyping of triple‐negative breast cancer: Implications for therapy
Published in Cancer (01-01-2015)“…Triple‐negative breast cancer (TNBC) is a heterogeneous disease; gene expression analyses recently identified 6 distinct TNBC subtypes, each of which displays…”
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TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes
Published in Journal of clinical oncology (20-12-2020)“…Olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor (PARPi), is approved for the treatment of human epidermal growth factor receptor 2 (HER2)-negative…”
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Greenland surface air temperature changes from 1981 to 2019 and implications for ice‐sheet melt and mass‐balance change
Published in International journal of climatology (01-01-2021)“…We provide an updated analysis of instrumental Greenland monthly temperature data to 2019, focusing mainly on coastal stations but also analysing ice‐sheet…”
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Divergent consensuses on Arctic amplification influence on midlatitude severe winter weather
Published in Nature climate change (01-01-2020)“…The Arctic has warmed more than twice as fast as the global average since the late twentieth century, a phenomenon known as Arctic amplification (AA)…”
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Current Landscape of Targeted Therapies for Hormone-Receptor Positive, HER2 Negative Metastatic Breast Cancer
Published in Frontiers in oncology (10-08-2018)“…The majority of deaths from MBC are in patients with hormone receptor (HR) positive, HER2 negative disease. Endocrine therapy (ET) remains the backbone of…”
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How do intermittency and simultaneous processes obfuscate the Arctic influence on midlatitude winter extreme weather events?
Published in Environmental research letters (18-03-2021)“…Pronounced changes in the Arctic environment add a new potential driver of anomalous weather patterns in midlatitudes that affect billions of people. Recent…”
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The bone-muscle connection in breast cancer: implications and therapeutic strategies to preserve musculoskeletal health
Published in Breast cancer research : BCR (23-11-2022)“…Breast cancer and its therapies frequently result in significant musculoskeletal morbidity. Skeletal complications include bone metastases, pain, bone loss,…”
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The toxins of vertically transmitted Spiroplasma
Published in Frontiers in microbiology (18-05-2023)“…Vertically transmitted (VT) microbial symbionts play a vital role in the evolution of their insect hosts. A longstanding question in symbiont research is what…”
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Conserved role of intragenic DNA methylation in regulating alternative promoters
Published in Nature (London) (08-07-2010)“…Methylation in the genes DNA methylation plays an important role in the maintenance of cell identity through its effect on gene expression. Methylation of 5′…”
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Role of atmospheric rivers in shaping long term Arctic moisture variability
Published in Nature communications (29-06-2024)“…Atmospheric rivers (ARs) reaching high-latitudes in summer contribute to the majority of climatological poleward water vapor transport into the Arctic. This…”
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Discrepancies between observations and climate models of large-scale wind-driven Greenland melt influence sea-level rise projections
Published in Nature communications (14-11-2022)“…While climate models project that Greenland ice sheet (GrIS) melt will continue to accelerate with climate change, models exhibit limitations in capturing…”
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Discovery and evolution of bunyavirids in arctic phantom midges and ancient bunyavirid-like sequences in insect genomes
Published in Journal of virology (01-08-2014)“…Bunyaviridae is a large family of RNA viruses chiefly comprised of vertebrate and plant pathogens. We discovered novel bunyavirids that are approximately…”
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Assessing the climatic and environmental impacts of mid‐tropospheric anticyclones over Alaska
Published in International journal of climatology (01-01-2018)“…ABSTRACT Ongoing climatic and cryospheric changes observed throughout the greater Alaska region are interconnected and often linked to oceanic and atmospheric…”
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Exercise as part of survivorship care in metastatic breast cancer: protocol for the randomized EMBody trial
Published in BMC cancer (12-09-2024)“…Exercise is associated with improved survival, physical functioning, treatment tolerability, and quality of life in early-stage breast cancer. These same…”
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Modeling double strand break susceptibility to interrogate structural variation in cancer
Published in Genome Biology (08-02-2019)“…Structural variants (SVs) are known to play important roles in a variety of cancers, but their origins and functional consequences are still poorly understood…”
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Recent Increased Warming of the Alaskan Marine Arctic Due to Midlatitude Linkages
Published in Advances in atmospheric sciences (2018)“…Alaskan Arctic waters have participated in hemispheric-wide Arctic warming over the last two decades at over twotimes the rate of global warming. During…”
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An exceptional family: Ophiocordyceps‐allied fungus dominates the microbiome of soft scale insects (Hemiptera: Sternorrhyncha: Coccidae)
Published in Molecular ecology (01-10-2017)“…Hemipteran insects of the suborder Sternorrhyncha are plant sap feeders, where each family is obligately associated with a specific bacterial endosymbiont that…”
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Molecular and clinical effects of aromatase inhibitor therapy on skeletal muscle function in early-stage breast cancer
Published in Scientific reports (10-01-2024)“…We evaluated biochemical changes in skeletal muscle of women with breast cancer initiating aromatase inhibitors (AI), including oxidation of ryanodine receptor…”
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Extreme weather and climate events in northern areas: A review
Published in Earth-science reviews (01-10-2020)“…The greatest impacts of climate change on ecosystems, wildlife and humans often arise from extreme events rather than changes in climatic means. Northern high…”
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