Search Results - "Ballesteros, M. Paloma"

Transferosomes as nanocarriers for drugs across the skin: Quality by design from lab to industrial scale by Fernández-García, Raquel, Lalatsa, Aikaterini, Statts, Larry, Bolás-Fernández, Francisco, Ballesteros, M. Paloma, Serrano, Dolores R.

“…[Display omitted] Transferosomes, also known as transfersomes, are ultradeformable vesicles for transdermal applications consisting of a lipid bilayer with…”
Get full text

Oral Fixed-Dose Combination Pharmaceutical Products: Industrial Manufacturing Versus Personalized 3D Printing by Fernández-García, Raquel, Prada, María, Bolás-Fernández, Francisco, Ballesteros, M. Paloma, Serrano, Dolores R.

“…Fixed-dose combination (FDC) products containing at least two different active pharmaceutical ingredients are designed to treat more effectively different…”
Get full text

Self-assembling, supramolecular chemistry and pharmacology of amphotericin B: Poly-aggregates, oligomers and monomers by Fernández-García, Raquel, Muñoz-García, Juan C., Wallace, Matthew, Fabian, Laszlo, González-Burgos, Elena, Gómez-Serranillos, M. Pilar, Raposo, Rafaela, Bolás-Fernández, Francisco, Ballesteros, M. Paloma, Healy, Anne Marie, Khimyak, Yaroslav Z., Serrano, Dolores R.

“…Antifungal drugs such as amphotericin B (AmB) interact with lipids and phospholipids located on fungal cell membranes to disrupt them and create pores, leading…”
Get full text

Application of Accelerated Predictive Stability Studies in Extemporaneously Compounded Formulations of Chlorhexidine to Assess the Shelf Life by González-González, Olga, Ballesteros, M Paloma, Torrado, Juan J, Serrano, Dolores R

“…Industrially fabricated medicines have a well-defined shelf life supported by rigorous studies before their approval for commercialization. However, the shelf…”
Get full text

Oral Particle Uptake and Organ Targeting Drives the Activity of Amphotericin B Nanoparticles by Serrano, Dolores R, Lalatsa, Aikaterini, Dea-Ayuela, M. Auxiliadora, Bilbao-Ramos, Pablo E, Garrett, Natalie L, Moger, Julian, Guarro, Josep, Capilla, Javier, Ballesteros, M. Paloma, Schätzlein, Andreas G, Bolás, Francisco, Torrado, Juan J, Uchegbu, Ijeoma F

“…There are very few drug delivery systems that target key organs via the oral route, as oral delivery advances normally address gastrointestinal drug…”
Get full text

Can amphotericin B and itraconazole be co-delivered orally? Tailoring oral fixed-dose combination coated granules for systemic mycoses by Fernández-García, Raquel, Walsh, David, O'Connell, Peter, Slowing, Karla, Raposo, Rafaela, Paloma Ballesteros, M., Jiménez-Cebrián, Aurora, Chamorro-Sancho, Manuel J., Bolás-Fernández, Francisco, Healy, Anne Marie, Serrano, Dolores R.

“…[Display omitted] The incidence and prevalence of invasive fungal infections have increased significantly over the last few years, leading to a global health…”
Get full text

Effect of aggregation state on the toxicity of different amphotericin B preparations by Espada, Raquel, Valdespina, Suriñe, Alfonso, Carlos, Rivas, German, Ballesteros, M. Paloma, Torrado, Juan J.

“…The aim of this work was to study the effect of aggregation of amphotericin B (AMB) in their toxicity. The aggregation of AMB depends on different formulation…”
Get full text

Co-Delivery of a High Dose of Amphotericin B and Itraconazole by Means of a Dry Powder Inhaler Formulation for the Treatment of Severe Fungal Pulmonary Infections by Celi, Salomé S, Fernández-García, Raquel, Afonso-Urich, Andreina I, Ballesteros, M. Paloma, Healy, Anne Marie, Serrano, Dolores R

“…Over the past few decades, there has been a considerable rise in the incidence and prevalence of pulmonary fungal infections, creating a global health problem…”
Get full text

Lecithin-based oil-in-water microemulsions for parenteral use: pseudoternary phase diagrams, characterization and toxicity studies by Moreno, Marco Antonio, Ballesteros, M Paloma, Frutos, Paloma

“…Pseudoternary phase diagrams have been constructed to evaluate the phase behavior of systems containing water/lecithin/polysorbate 80/isopropyl myristate at…”
Get more information

Comparative pharmacokinetics and safety of a novel lyophilized amphotericin B lecithin-based oil–water microemulsion and amphotericin B deoxycholate in animal models by Brime, Begoña, Frutos, Paloma, Bringas, Pilar, Nieto, Ana, Ballesteros, M. Paloma, Frutos, Gloria

“…Amphotericin B (AmB) has been a most effective systemic antifungal agent, but its use is circumscribed by the dose-limiting toxicity of the conventional…”
Get full text