Search Results - "Baller, Joshua A"
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Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
Published in Nucleic acids research (01-07-2011)“…TALENs are important new tools for genome engineering. Fusions of transcription activator-like (TAL) effectors of plant pathogenic Xanthomonas spp. to the FokI…”
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Transcription Activator-Like Effector Nucleases Enable Efficient Plant Genome Engineering
Published in Plant physiology (Bethesda) (01-01-2013)“…The ability to precisely engineer plant genomes offers much potential for advancing basic and applied plant biology. Here, we describe methods for the targeted…”
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The lung tissue microbiota of mild and moderate chronic obstructive pulmonary disease
Published in Microbiome (09-01-2018)“…Oral taxa are often found in the chronic obstructive pulmonary disease (COPD) lung microbiota, but it is not clear if this is due to a physiologic process such…”
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Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways
Published in Genome research (01-03-2013)“…Improved methods for engineering sequence-specific nucleases, including zinc finger nucleases (ZFNs) and TAL effector nucleases (TALENs), have made it possible…”
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A nucleosomal surface defines an integration hotspot for the Saccharomyces cerevisiae Ty1 retrotransposon
Published in Genome research (01-04-2012)“…Ty1, the most abundant retrotransposon in Saccharomyces cerevisiae, integrates preferentially upstream of genes transcribed by RNA polymerase III (Pol III)…”
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Silencing is noisy: population and cell level noise in telomere-adjacent genes is dependent on telomere position and sir2
Published in PLoS genetics (01-07-2014)“…Cell-to-cell gene expression noise is thought to be an important mechanism for generating phenotypic diversity. Furthermore, telomeric regions are major sites…”
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Access to DNA establishes a secondary target site bias for the yeast retrotransposon Ty5
Published in Proceedings of the National Academy of Sciences - PNAS (20-12-2011)“…Integration sites for many retrotransposons and retroviruses are determined by interactions between retroelement-encoded integrases and specific DNA-bound…”
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The Three Clades of the Telomere-Associated TLO Gene Family of Candida albicans Have Different Splicing, Localization, and Expression Features
Published in Eukaryotic Cell (01-10-2012)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Comprehensive Functional Analysis of the Enterococcus faecalis Core Genome Using an Ordered, Sequence-Defined Collection of Insertional Mutations in Strain OG1RF
Published in mSystems (01-09-2018)“…Enterococcus faecalis is a common commensal bacterium in animal gastrointestinal (GI) tracts and a leading cause of opportunistic infections of humans in the…”
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Origin replication complex binding, nucleosome depletion patterns, and a primary sequence motif can predict origins of replication in a genome with epigenetic centromeres
Published in mBio (02-09-2014)“…Origins of DNA replication are key genetic elements, yet their identification remains elusive in most organisms. In previous work, we found that centromeres…”
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An RNA polymerase III subunit determines sites of retrotransposon integration
Published in Science (American Association for the Advancement of Science) (01-05-2015)“…Mobile genetic elements are ubiquitous. Their integration site influences genome stability and gene expression. The Ty1 retrotransposon of the yeast…”
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Using the Daphnia magna Transcriptome to Distinguish Water Source: Wetland and Stormwater Case Studies
Published in Environmental toxicology and chemistry (01-09-2022)“…A major challenge in ecotoxicology is accurately and sufficiently measuring chemical exposures and biological effects given the presence of complex and dynamic…”
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Histone H2AX and the small RNA pathway modulate both non-homologous end-joining and homologous recombination in plants
Published in Mutation research (01-01-2016)“…Using a zinc finger nuclease (ZFN) that creates a site-specific DNA double-strand break (DSB) at the endogenous ADH1 locus, we provide genetic evidence that…”
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Silencing Is Noisy: Population and Cell Level Noise in Telomere-Adjacent Genes Is Dependent on Telomere Position and Sir2: e1004436
Published in PLoS genetics (01-07-2014)“…Cell-to-cell gene expression noise is thought to be an important mechanism for generating phenotypic diversity. Furthermore, telomeric regions are major sites…”
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Retrotransposons. An RNA polymerase III subunit determines sites of retrotransposon integration
Published in Science (American Association for the Advancement of Science) (01-05-2015)“…Mobile genetic elements are ubiquitous. Their integration site influences genome stability and gene expression. The Ty1 retrotransposon of the yeast…”
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Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
Published in Nucleic acids research (01-09-2011)Get full text
Journal Article -
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Transcription Activator-Like Effector Nucleases Enable Efficient Plant Genome Engineering1[W][OA]
Published in Plant physiology (Bethesda) (02-11-2012)“…The ability to precisely engineer plant genomes offers much potential for advancing basic and applied plant biology. Here, we describe methods for the targeted…”
Get full text
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The Lung Tissue Microbiota of Mild and Moderate Chronic Obstructive Pulmonary Disease
Published in Open forum infectious diseases (01-10-2017)Get full text
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Comprehensive Functional Analysis of the Enterococcus faecalis Core Genome Using an Ordered, Sequence-Defined Collection of Insertional Mutations in Strain OG1RF
Published in mSystems (01-10-2018)“…ABSTRACT Enterococcus faecalis is a common commensal bacterium in animal gastrointestinal (GI) tracts and a leading cause of opportunistic infections of humans…”
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