Search Results - "Ballard, Clive"
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Treatment Combinations for Alzheimer's Disease: Current and Future Pharmacotherapy Options
Published in Journal of Alzheimer's disease (01-01-2019)“…Although Alzheimer's disease (AD) is the world's leading cause of dementia and the population of patients with AD continues to grow, no new therapies have been…”
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Incidence and prediction of falls in dementia: a prospective study in older people
Published in PloS one (13-05-2009)“…Falls are a major cause of morbidity and mortality in dementia, but there have been no prospective studies of risk factors for falling specific to this patient…”
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The prognosis of dementia with Lewy bodies
Published in Lancet neurology (01-05-2017)“…Summary Dementia with Lewy bodies is the second most common form of neurodegenerative dementia, yet scarce evidence is available about its prognosis and…”
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Dementia in Down's syndrome
Published in Lancet neurology (01-05-2016)“…Summary Down's syndrome is the most common genetic cause of learning difficulties, and individuals with this condition represent the largest group of people…”
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Cognitive impairment in patients with Parkinson's disease: diagnosis, biomarkers, and treatment
Published in Lancet neurology (01-08-2012)“…Summary Dementia is one of the most common and important aspects of Parkinson's disease and has consequences for patients and caregivers, and has…”
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Persistent depressive symptoms are associated with frontal regional atrophy in patients with Alzheimer's disease
Published in International journal of geriatric psychiatry (01-01-2023)“…Background Depression in individuals with Alzheimer's disease (AD) is common, difficult to treat and inadequately understood. Previous studies have identified…”
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Putting brain training to the test
Published in Nature (London) (10-06-2010)“…'Brain training', or the goal of improved cognitive function through the regular use of computerized tests, is a multimillion-pound industry, yet in our view…”
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Pimavanserin for patients with Parkinson's disease psychosis: a randomised, placebo-controlled phase 3 trial
Published in The Lancet (British edition) (08-02-2014)“…Summary Background Parkinson's disease psychosis, which includes hallucinations and delusions, is frequent and debilitating in people with Parkinson's disease…”
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Neuroleptic drugs in dementia: benefits and harm
Published in Nature reviews. Neuroscience (01-06-2006)“…Neuroleptic (antipsychotic) drugs are often used to treat psychiatric symptoms frequently seen in dementia, but their use is controversial. We present a new…”
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Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium
Published in Neurology (04-07-2017)“…The Dementia with Lewy Bodies (DLB) Consortium has refined its recommendations about the clinical and pathologic diagnosis of DLB, updating the previous…”
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Impact of person-centred care training and person-centred activities on quality of life, agitation, and antipsychotic use in people with dementia living in nursing homes: A cluster-randomised controlled trial
Published in PLoS medicine (06-02-2018)“…Agitation is a common, challenging symptom affecting large numbers of people with dementia and impacting on quality of life (QoL). There is an urgent need for…”
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Evaluation of the efficacy of pimavanserin in the treatment of agitation and aggression in patients with Alzheimer's disease psychosis: A post hoc analysis
Published in International journal of geriatric psychiatry (01-11-2020)“…Objectives Patients with Alzheimer's disease psychosis (ADP) commonly experience concomitant agitation and aggression. We investigated whether a reduction in…”
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Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science
Published in The Lancet. Psychiatry (01-06-2020)“…The coronavirus disease 2019 (COVID-19) pandemic is having a profound effect on all aspects of society, including mental health and physical health. We explore…”
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Depression in Parkinson disease—epidemiology, mechanisms and management
Published in Nature reviews. Neurology (01-01-2012)“…Depression is a common symptom in patients with Parkinson disease (PD), and is found at higher rates in these individuals than in healthy populations or…”
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Drug repositioning and repurposing for Alzheimer disease
Published in Nature reviews. Neurology (01-12-2020)“…Drug repositioning and repurposing can enhance traditional drug development efforts and could accelerate the identification of new treatments for individuals…”
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The psychosis spectrum in Parkinson disease
Published in Nature reviews. Neurology (01-02-2017)“…Key Points Parkinson disease (PD) psychosis refers to a spectrum of illusions, hallucinations and delusions that occur throughout the disease course Evolving…”
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Tip of the Iceberg: Assessing the Global Socioeconomic Costs of Alzheimer's Disease and Related Dementias and Strategic Implications for Stakeholders
Published in Journal of Alzheimer's disease (01-01-2019)“…While it is generally understood that Alzheimer's disease (AD) and related dementias (ADRD) is one of the costliest diseases to society, there is widespread…”
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The Effect of an Online Cognitive Training Package in Healthy Older Adults: An Online Randomized Controlled Trial
Published in Journal of the American Medical Directors Association (01-11-2015)“…Abstract Introduction Cognitive training (CT) offers a potential approach for dementia prevention and maintenance of cognitive function in older adults. Online…”
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The Response of Agitated Behavior to Pain Management in Persons with Dementia
Published in The American journal of geriatric psychiatry (01-07-2014)“…Objectives Behavioral disturbances and pain are common in nursing home (NH) patients with dementia. An association between pain and increased agitation has…”
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Associations between cognitively stimulating leisure activities, cognitive function and age-related cognitive decline
Published in International journal of geriatric psychiatry (01-04-2015)“…Objectives Emerging literature suggests that lifestyle factors may play an important role in reducing age‐related cognitive decline. There have, however, been…”
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