Search Results - "Ballantyne, CM"

Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol by Ray, Kausik K, Bays, Harold E, Catapano, Alberico L, Lalwani, Narendra D, Bloedon, LeAnne T, Sterling, Lulu R, Robinson, Paula L, Ballantyne, Christie M

“…Short-term studies indicate that bempedoic acid, an ATP citrate lyase inhibitor, reduces LDL cholesterol levels. In a 1-year trial, bempedoic acid added to…”
Get full text

Effect of Very High-Intensity Statin Therapy on Regression of Coronary Atherosclerosis: The ASTEROID Trial by Nissen, Steven E, Nicholls, Stephen J, Sipahi, Ilke, Libby, Peter, Raichlen, Joel S, Ballantyne, Christie M, Davignon, Jean, Erbel, Raimund, Fruchart, Jean Charles, Tardif, Jean-Claude, Schoenhagen, Paul, Crowe, Tim, Cain, Valerie, Wolski, Kathy, Goormastic, Marlene, Tuzcu, E. Murat, ASTEROID Investigators, for the

“…CONTEXT Prior intravascular ultrasound (IVUS) trials have demonstrated slowing or halting of atherosclerosis progression with statin therapy but have not shown…”
Get full text

Low-grade systemic inflammation and the development of type 2 diabetes: The atherosclerosis Risk in Communities Study by DUNCAN, Bruce B, SCHMIDT, Maria Inês, PANKOW, James S, BALLANTYNE, Christie M, COUPER, David, VIGO, Alvaro, HOOGEVEEN, Ron, FOLSOM, Aaron R, HEISS, Gerardo

“…To examine the association of low-grade systemic inflammation with diabetes, as well as its heterogeneity across subgroups, we designed a case-cohort study…”
Get full text

Metabolic Syndrome and 11-Year Risk of Incident Cardiovascular Disease in the Atherosclerosis Risk in Communities Study by McNeill, Ann Marie, Rosamond, Wayne D, Girman, Cynthia J, Golden, Sherita Hill, Schmidt, Maria I, East, Honey E, Ballantyne, Christie M, Heiss, Gerardo

“…OBJECTIVE:-- To assess the magnitude of the association between the National Cholesterol Education Program's Third Adult Treatment Panel Report (ATP III)…”
Get full text

PCSK9 Inhibitors in the Management of Cardiovascular Risk: A Practical Guidance by Jia, Xiaoming, Rifai, Mahmoud Al, Saeed, Anum, Ballantyne, Christie M, Virani, Salim S

“…Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are potent medications in the toolkit for treatment of atherosclerotic cardiovascular disease…”
Get full text

Identifying Individuals at High Risk for Diabetes: The Atherosclerosis Risk in Communities study by Schmidt, Maria Inês, Duncan, Bruce B, Bang, Heejung, Pankow, James S, Ballantyne, Christie M, Golden, Sherita H, Folsom, Aaron R, Chambless, Lloyd E

“…OBJECTIVE:--To develop and evaluate clinical rules to predict risk for diabetes in middle-aged adults. RESEARCH DESIGN AND METHODS--The Atherosclerosis Risk in…”
Get full text

Circulating Inflammatory Proteins Associated with Dementia Risk in Older Adult Cancer Survivors in the Atherosclerosis Risk in Communities (ARIC) Study by Ugoji, CC, Walker, KA, Dean, LT, Gross, AL, Ballantyne, CM, Butler, K, Hoogeveen, RC, Joshu, C, Mosley, TH, Prizment, A, Sharrett, AR, Tin, A, Coresh, J, Platz, EA

“…Background Inflammation is linked to cognitive impairment (CI) in cancer survivors. But its role in survivors who develop dementia is unclear. Methods We…”
Get full text

Comparison of the Instructional Efficacy of Internet-Based CME With Live Interactive CME Workshops: A Randomized Controlled Trial by Fordis, Michael, King, Jason E, Ballantyne, Christie M, Jones, Peter H, Schneider, Katharine H, Spann, Stephen J, Greenberg, Stephen B, Greisinger, Anthony J

“…CONTEXT Despite evidence that a variety of continuing medical education (CME) techniques can foster physician behavioral change, there have been no randomized…”
Get full text

Adiponectin and the development of type 2 diabetes: The Atherosclerosis Risk in Communities Study by DUNCAN, Bruce B, SCHMIDT, Maria Inês, PANKOW, James S, BANG, Heejung, COUPER, David, BALLANTYNE, Christie M, HOOGEVEEN, Ron C, HEISS, Gerardo

“…Adipocyte-derived secretory proteins have been increasingly linked to diabetes. To investigate whether adiponectin, a major adipocyte secretory protein,…”
Get full text

Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: A prospective, randomized, double-blind trial by BALLANTYNE, Christie M, HOURI, John, NOTARBARTOLO, Alberto, MELANI, Lorenzo, LIPKA, Leslie J, SURESH, Ramachandran, SUN, Steven, LEBEAUT, Alexandre P, SAGER, Philip T, VELTRI, Enrico P

“…Despite the established efficacy of statins, many patients do not achieve recommended LDL cholesterol (LDL-C) goals. Contributing factors may be inadequate…”
Get full text

Coronary heart disease prediction from lipoprotein cholesterol levels, triglycerides, lipoprotein(a), apolipoproteins A-I and B, and HDL density subfractions: The atherosclerosis risk in Communities (ARIC) Study by SHARRETT, A. R, BALLANTYNE, C. M, COADY, S. A, HEISS, G, SORLIE, P. D, CATELLIER, D, PATSCH, W

“…Despite consensus on the need for blood cholesterol reductions to prevent coronary heart disease (CHD), available evidence on optimal cholesterol levels or the…”
Get full text

Rationale and design of the dal-OUTCOMES trial: Efficacy and safety of dalcetrapib in patients with recent acute coronary syndrome by Schwartz, Gregory G., MD, PhD, Olsson, Anders G., MD, PhD, Ballantyne, Christie M., MD, Barter, Phillip J., MD, PhD, Holme, Ingar M., PhD, Kallend, David, MB, BS, Leiter, Lawrence A., MD, Leitersdorf, Eran, MD, McMurray, John J.V., MD, Shah, Prediman K., MD, Tardif, Jean-Claude, MD, Chaitman, Bernard R., MD, Duttlinger-Maddux, Regina, PhD, Mathieson, John, PhD

“…Background Despite contemporary therapies for acute coronary syndrome (ACS), morbidity and mortality remain high. Low levels of high-density lipoprotein (HDL)…”
Get full text

Efficacy and safety of ezetimibe co-administered with simvastatin compared with atorvastatin in adults with hypercholesterolemia by Ballantyne, Christie M, Blazing, Michael A, King, Thomas R, Brady, William E, Palmisano, Joanne

“…This study compared the efficacy and safety of co-administered ezetimibe + simvastatin with atorvastatin monotherapy in adults with hypercholesterolemia. Seven…”
Get full text

Results of the National Cholesterol Education (NCEP) Program Evaluation Project Utilizing Novel E-Technology (NEPTUNE) II Survey and Implications for Treatment Under the Recent NCEP Writing Group Recommendations by Davidson, Michael H., Maki, Kevin C., Pearson, Thomas A., Pasternak, Richard C., Deedwania, Prakash C., McKenney, James M., Fonarow, Gregg C., Maron, David J., Ansell, Benjamin J., Clark, Luther T., Ballantyne, Christie M.

“…The most recent national survey of compliance with the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) guidelines was completed…”
Get full text

A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis by Chen, Suet N, Ballantyne, Christie M, Gotto, Jr, Antonio M, Tan, Yanli, Willerson, James T, Marian, Ali J

“…We sought to determine the effects of PCSK9 variants on plasma low-density lipoprotein cholesterol (LDL-C) levels, severity of coronary atherosclerosis, and…”
Get full text

Plasma lipid profile and incident ischemic stroke: The Atherosclerosis Risk in Communities (ARIC) Study by SHAHAR, Eyal, CHAMBLESS, Lloyd E, ROSAMOND, Wayne D, BOLAND, Lori L, BALLANTYNE, Christie M, MCGOVERN, Paul G, SHARRETT, A. Richey

“…The role of circulating lipids and lipoproteins in the pathogenesis of ischemic stroke remains uncertain despite 3 decades of research. We examined this issue…”
Get full text

Endothelial Lipase Is a Major Genetic Determinant for High-Density Lipoprotein Concentration, Structure, and Metabolism by Ma, Ke, Cilingiroglu, Mehmet, Otvos, James D., Ballantyne, Christie M., Marian, Ali J., Chan, Lawrence

“…High-density lipoprotein (HDL) protects against atherosclerosis. Endothelial lipase (EL) has been postulated to be involved in lipoprotein, and possibly HDL,…”
Get full text

Conditional risk factors for atherosclerosis by Kullo, Iftikhar J, Ballantyne, Christie M

“…Although most patients who experience a coronary heart disease (CHD) event have one or more of the conventional risk factors for atherosclerosis, so do many…”
Get more information

Influence of low high-density lipoprotein cholesterol and elevated triglyceride on coronary heart disease events and response to Simvastatin therapy in 4S by BALLANTYNE, Christie M, OLSSON, Anders G, COOK, Thomas J, MERCURI, Michele F, PEDERSEN, Terje R, KJEKSHUS, John

“…Patients with low HDL cholesterol (HDL-C) and elevated triglyceride had an increased risk for coronary heart disease (CHD) events and received the greatest…”
Get full text

Adiponectin, Inflammation, and the Expression of the Metabolic Syndrome in Obese Individuals: The Impact of Rapid Weight Loss through Caloric Restriction by Xydakis, Antonios M., Case, Christopher C., Jones, Peter H., Hoogeveen, Ron C., Liu, Mine-Yine, Smith, E. O’Brian, Nelson, Kathleen W., Ballantyne, Christie M.

“…Severe obesity increases the prevalence of the metabolic syndrome, and moderate acute weight loss with a very low-calorie diet in obese subjects with the…”
Get full text