Search Results - "Ballantine, Stuart P."

Quinolines as a novel structural class of potent and selective PDE4 inhibitors. Optimisation for inhaled administration by Woodrow, Michael D., Ballantine, Stuart P., Barker, Michael D., Clarke, Beth J., Dawson, John, Dean, Tony W., Delves, Christopher J., Evans, Brian, Gough, Sharon L., Guntrip, Steven B., Holman, Stuart, Holmes, Duncan S., Kranz, Michael, Lindvaal, Mika K., Lucas, Fiona S., Neu, Margarete, Ranshaw, Lisa E., Solanke, Yemisi E., Somers, Don O., Ward, Peter, Wiseman, Joanne O.

“…A series of quinoline-3-carboxamides has been identified as potent inhibitors of PDE4. The SAR has been explored and these studies have highlighted compound 4…”
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Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors by Hamblin, J. Nicole, Angell, Tony D.R., Ballantine, Stuart P., Cook, Caroline M., Cooper, Anthony W.J., Dawson, John, Delves, Christopher J., Jones, Paul S., Lindvall, Mika, Lucas, Fiona S., Mitchell, Charlotte J., Neu, Margarete Y., Ranshaw, Lisa E., Solanke, Yemisi E., Somers, Don O., Wiseman, Joanne O.

“…A series of pyrazolo[3,4- b]pyridine-5-carboxamides has been identified as potent inhibitors of PDE4. The SAR has been explored and these studies have…”
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Pyrazolopyridines as potent PDE4B inhibitors: 5-Heterocycle SAR by Mitchell, Charlotte J., Ballantine, Stuart P., Coe, Diane M., Cook, Caroline M., Delves, Christopher J., Dowle, Mike D., Edlin, Chris D., Hamblin, J. Nicole, Holman, Stuart, Johnson, Martin R., Jones, Paul S., Keeling, Sue E., Kranz, Michael, Lindvall, Mika, Lucas, Fiona S., Neu, Margarete, Solanke, Yemisi E., Somers, Don O., Trivedi, Naimisha A., Wiseman, Joanne O.

“…Several series of pyrazolo[3,4-b]pyridine-5-heterocycles have been identified as potent inhibitors of PDE4B. Molecular modelling and X-ray crystallography on…”
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Single Amino Acid Substitutions Disrupt Tetramer Formation in the Dihydroneopterin Aldolase Enzyme of Pneumocystis carinii by Thomas, M. Carmen, Ballantine, Stuart P, Bethell, Susanne S, Bains, Satty, Kellam, Paul, Delves, Chris J

“…In the opportunistic pathogen Pneumocystis carinii, dihydroneopterin aldolase function is expressed as the N-terminal portion of the multifunctional folic acid…”
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Expression of Tetanus Toxin Fragment C in E. coli: Its Purification and Potential Use as a Vaccine by Makoff, Andrew J, Ballantine, Stuart P, Smallwood, Althea E, Fairweather, Neil F

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Reassignment of the gene encoding the Escherichia coli hydrogenase 2 small subunit--identification of a soluble precursor of the small subunit in a hypB mutant by Sargent, F, Ballantine, S P, Rugman, P A, Palmer, T, Boxer, D H

“…An active tryptic fragment of hydrogenase 2 from Escherichia coli has been isolated from the periplasmic face of the cytoplasmic membrane, and the large and…”
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Two domains with amino-acid sequence similarity are required for dihydroneopterin aldolase function in the multifunctional folic acid synthesis fas protein of Pneumocystis carinii by Volpe, Filippo, Ballantine, Stuart P., Delves, Chris J.

“…The folic acid synthesized gene ( fas) of Pneumocystis carinii (Pc) codes for a multifunctional enzyme (Fas) known to catalyse three consecutive steps leading…”
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Recombinant Bordetella pertussis pertactin (P69) from the yeast Pichia pastoris: high-level production and immunological properties by Romanos, M A, Clare, J J, Beesley, K M, Rayment, F B, Ballantine, S P, Makoff, A J, Dougan, G, Fairweather, N F, Charles, I G

“…Acellular whooping cough vaccines are based on pertussis toxoid but their effectiveness may be increased by the addition of other Bordetella pertussis…”
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Reassignment of the gene encoding the Escherichia coli hydrogenase 2 small subunit by Sargent, Frank, Ballantine, Stuart P., Rugman, Paul A., Palmer, Tracy, Boxer, David H.

“…An active tryptic fragment of hydrogenase 2 from Escherichia coli has been isolated from the periplasmic face of the cytoplasmic membrane, and the large and…”
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The multifunctional folic acid synthesis fas gene of Pneumocystis carinii encodes dihydroneopterin aldolase, hydroxymethyldihydropterin pyrophosphokinase and dihydropteroate synthase by VOLPE, Filippo, BALLANTINE, Stuart P., DELVES, Chris J.

“…The nucleotide sequence of a folic acid synthesis (fas) gene from Pneumocystis carinii contains an open reading frame (ORF) that predicts a protein of 740…”
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Functional cloning of the dihydropteroate synthase gene of Staphylococcus haemolyticus by Kellam, P, Dallas, W S, Ballantine, S P, Delves, C J

“…A 1,7-kilobase fragment of the Staphylococcus haemolyticus chromosome containing the dihydropteroate synthase gene has been cloned by complementation in a…”
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Isolation and characterisation of a soluble active fragment of hydrogenase isoenzyme 2 from the membranes of anaerobically grown Escherichia coli by BALLANTINE, Stuart P., BOXER, David H.

“…An active tryptic fragment of membrane‐bound hydrogenase isoenzyme 2 from anaerobically grown Escherichia coli has been purified. The soluble enzyme derivative…”
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