Search Results - "Ball, Amy L"

The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review by Jones, Samantha W, Ball, Amy L, Chadwick, Amy E, Alfirevic, Ana

“…The triad of drug efficacy, toxicity and resistance underpins the risk-benefit balance of all therapeutics. The application of pharmacogenomics has the…”
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Identification of the Additional Mitochondrial Liabilities of 2-Hydroxyflutamide When Compared With its Parent Compound, Flutamide in HepG2 Cells by Ball, Amy L, Kamalian, Laleh, Alfirevic, Ana, Lyon, Jonathan J, Chadwick, Amy E

“…The androgen receptor antagonist, flutamide, is strongly associated with idiosyncratic drug-induced liver injury (DILI). Following administration, flutamide…”
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Efficacy of Lower Extremity Cycling Interventions for Youth with Intellectual Disabilities: A Systematic Review by Fragala-Pinkham, Maria A., Ball, Amy L., Jeffries, Lynn M.

“…To systematically examine the efficacy of lower extremity cycling interventions for youth with intellectual disability (ID). Seven databases were searched from…”
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Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers by Ball, Amy L., Bloch, Katarzyna M., Rainbow, Lucille, Liu, Xuan, Kenny, John, Lyon, Jonathan J., Gregory, Richard, Alfirevic, Ana, Chadwick, Amy E.

“…Mitochondrial DNA (mtDNA) is highly polymorphic and encodes 13 proteins which are critical to the production of ATP via oxidative phosphorylation. As mtDNA is…”
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