Search Results - "Balkhiyarova, Zhanna"
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Integrating Common Risk Factors with Polygenic Scores Improves the Prediction of Type 2 Diabetes
Published in International journal of molecular sciences (04-01-2023)“…We tested associations between 13 established genetic variants and type 2 diabetes (T2D) in 1371 study participants from the Volga-Ural region of the Eurasian…”
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Mendelian Randomization Analysis Identifies Inverse Causal Relationship between External Eating and Metabolic Phenotypes
Published in Nutrients (13-04-2024)“…Disordered eating contributes to weight gain, obesity, and type 2 diabetes (T2D), but the precise mechanisms underlying the development of different eating…”
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Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension
Published in Nature communications (06-01-2024)“…Pulmonary arterial hypertension (PAH) is characterised by pulmonary vascular remodelling causing premature death from right heart failure. Established DNA…”
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Multilocus associations of inflammatory genes with the risk of type 1 diabetes
Published in Gene (30-07-2019)“…Genome-wide association studies have captured a large proportion of genetic variation related to type 1 diabetes mellitus (T1D). However, most of these studies…”
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DISENTANGLING THE SHARED HERITABILITY OF THE PREDISPOSITION TO HYPERTENSION AND TYPE 2 DIABETES
Published in Journal of hypertension (01-06-2022)“…Objective: Genome-wide association studies (GWAS) identified over 900 genetic loci for blood pressure traits and over 200 for type 2 diabetes (T2D)…”
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POLYGENIC SCORES TOGETHER WITH COMMON RISK FACTORS ARE INFORMATIVE PREDICTORS OF METABOLIC HEALTH
Published in Journal of hypertension (01-06-2023)“…Objective: Type 2 diabetes (T2D) is a complex metabolic disorder influenced by various genetic, behavioural, and environmental factors, with ageing and obesity…”
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Bidirectional Mendelian Randomization and Multiphenotype GWAS Show Causality and Shared Pathophysiology Between Depression and Type 2 Diabetes
Published in Diabetes care (01-09-2023)“…Depression is a common comorbidity of type 2 diabetes. We assessed the causal relationships and shared genetics between them. We applied two-sample,…”
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Relationship between glucose homeostasis and obesity in early life—a study of Italian children and adolescents
Published in Human molecular genetics (03-03-2022)“…Abstract Epidemic obesity is the most important risk factor for prediabetes and type 2 diabetes (T2D) in youth as it is in adults. Obesity shares…”
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Abdominal obesity is a more important causal risk factor for pancreatic cancer than overall obesity
Published in European journal of human genetics : EJHG (01-08-2023)“…Obesity and type 2 diabetes (T2D) are associated with increased risk of pancreatic cancer. Here we assessed the relationship between pancreatic cancer and two…”
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DISENTANGLING THE SHARED HERITABILITY OF THE PREDISPOSITION TO HYPERTENSION AND TYPE 2 DIABETES
Published in Journal of hypertension (01-06-2022)Get full text
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Measurement invariance testing of the patient health questionnaire-9 (PHQ-9) across people with and without diabetes mellitus from the NHANES, EMHS and UK Biobank datasets
Published in Journal of affective disorders (01-09-2021)“…•The PHQ-9 was measurement invariant (MI) across people with and without diabetes.•MI was found for 1-factor and a 2-factor (somatic and non-somatic items)…”
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Bifidobacterium Is Enriched in Gut Microbiome of Kashmiri Women with Polycystic Ovary Syndrome
Published in Genes (18-02-2022)“…Polycystic ovary syndrome (PCOS) is a very common endocrine condition in women in India. Gut microbiome alterations were shown to be involved in PCOS, yet it…”
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