Search Results - "Balint Lahat, Nora"
-
1
Large language model (ChatGPT) as a support tool for breast tumor board
Published in NPJ breast cancer (30-05-2023)“…Large language models (LLM) such as ChatGPT have gained public and scientific attention. The aim of this study is to evaluate ChatGPT as a support tool for…”
Get full text
Journal Article -
2
Divergence of mutational signatures in association with breast cancer subtype
Published in Molecular carcinogenesis (01-11-2022)“…Abnormal molecular processes occurring throughout the genome leave distinct somatic mutational patterns termed mutational signatures. Exploring the…”
Get full text
Journal Article -
3
ESR1 mutations are frequent in newly diagnosed metastatic and loco-regional recurrence of endocrine-treated breast cancer and carry worse prognosis
Published in Breast cancer research : BCR (03-02-2020)“…Emerging mutations in the ESR1 gene that encodes for the estrogen receptor (ER) are associated with resistance to endocrine therapy. ESR1 mutations rarely…”
Get full text
Journal Article -
4
Breast cancer screening in BRCA1/2 pathogenic sequence variant carriers during pregnancy and lactation
Published in Clinical imaging (01-07-2024)“…Women harboring germline BRCA1/BRCA2 pathogenic sequence variants (PSVs) are at an increased risk for breast cancer. There are no established guidelines for…”
Get full text
Journal Article -
5
mRNA-seq whole transcriptome profiling of fresh frozen versus archived fixed tissues
Published in BMC genomics (30-05-2018)“…The main bottleneck for genomic studies of tumors is the limited availability of fresh frozen (FF) samples collected from patients, coupled with comprehensive…”
Get full text
Journal Article -
6
TNFR2+ TILs are significantly associated with improved survival in triple-negative breast cancer patients
Published in Cancer Immunology, Immunotherapy (01-07-2020)“…In view of the relatively limited efficacy of immunotherapies targeting the PD-1–PD-L1 axis in triple-negative breast cancer (TNBC) and of published reports on…”
Get full text
Journal Article -
7
Modeling epithelial-mesenchymal transition in patient-derived breast cancer organoids
Published in Frontiers in oncology (14-10-2024)“…Cellular plasticity is enhanced by dedifferentiation processes such as epithelial-mesenchymal transition (EMT). The dynamic and transient nature of EMT-like…”
Get full text
Journal Article -
8
Class Effect Unveiled: PPARγ Agonists and MEK Inhibitors in Cancer Cell Differentiation
Published in Cells (Basel, Switzerland) (09-09-2024)“…Epithelial-to-mesenchymal transition (EMT) plays a major role in breast cancer progression and the development of drug resistance. We have previously…”
Get full text
Journal Article -
9
Correction to: ESR1 mutations are frequent in newly diagnosed metastatic and loco-regional recurrence of endocrine-treated breast cancer and carry worse prognosis
Published in Breast cancer research : BCR (12-03-2020)“…After the publication of the original article [1], we were notified the upper panel of the Fig. 1, where the patients' codes are listed, was cropped by mistake…”
Get full text
Journal Article -
10
Extracellular Vesicular Transmission of miR-423-5p from HepG2 Cells Inhibits the Differentiation of Hepatic Stellate Cells
Published in Cells (Basel, Switzerland) (23-05-2022)“…Liver fibrosis (LF) is a major cause of morbidity and mortality worldwide. Hepatic stellate cells (HSCs) are the primary source of extracellular matrix in the…”
Get full text
Journal Article -
11
Recurrent Metastatic Spread to a Percutaneous Gastrostomy Site in a Patient With Squamous Cell Carcinoma of the Tongue: A Case Report and Review of the Literature
Published in Journal of oral and maxillofacial surgery (01-04-2014)“…Patients diagnosed with head and neck squamous cell cancer (HNSCC) frequently develop dysphagia and odynophagia owing to advancing disease or as a result of…”
Get full text
Journal Article -
12
Chemotherapy Shifts the Balance in Favor of CD8+ TNFR2+ TILs in Triple-Negative Breast Tumors
Published in Cells (Basel, Switzerland) (08-06-2021)“…Triple-negative breast cancer (TNBC) is primarily treated via chemotherapy; in parallel, efforts are made to introduce immunotherapies into TNBC treatment…”
Get full text
Journal Article -
13
Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions
Published in Cell (29-09-2022)“…Cancer-microbe associations have been explored for centuries, but cancer-associated fungi have rarely been examined. Here, we comprehensively characterize the…”
Get full text
Journal Article -
14
Unusual variant of invasive ductal carcinoma suggesting metaplastic melanocytic differentiation
Published in Human pathology : case reports (01-03-2021)“…Metaplastic carcinoma of the breast is a general definition referring to a heterogeneous group of neoplasms characterized by a mixture of adenocarcinoma with…”
Get full text
Journal Article -
15
Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4 + and PDPN + CAFs to clinical outcome
Published in Nature cancer (01-07-2020)“…Tumors are supported by cancer-associated fibroblasts (CAFs). CAFs are heterogeneous and carry out distinct cancer-associated functions. Understanding the full…”
Get full text
Journal Article -
16
Clinical experience on the limited role of ultrasound for breast cancer screening in BRCA1 and BRCA2 mutations carriers aged 30–39 years
Published in Clinical imaging (01-12-2024)“…In BRCA germline pathogenic sequence variants (PSV) carriers aged 30–39 years imaging is recommended at six-month intervals. The European society for medical…”
Get full text
Journal Article -
17
Incidental Axillary Lymphadenopathy Found on Radiation Planning Computed Tomography
Published in International journal of radiation oncology, biology, physics (01-08-2024)“…The aim of this study was to evaluate the rate of axillary node–positive disease in patients with early breast cancer who had a suspicious axillary lymph node…”
Get full text
Journal Article -
18
CCL2 blockade combined with PD-1/P-selectin immunomodulators impedes breast cancer brain metastasis
Published in Brain (London, England : 1878) (25-10-2024)“…Over the last two decades, the diagnosis and treatment of breast cancer patients have considerably improved. However, brain metastases remain a major clinical…”
Get full text
Journal Article -
19
Abstract P6-03-01: Mapping a personalized chemo-resistome in breast cancer patients by longitudinal transcriptomics
Published in Cancer research (Chicago, Ill.) (15-02-2020)“…Background: Understanding resistance mechanisms to chemotherapy is key to improving therapeutic outcomes. Despite the considerable importance of tumor drug…”
Get full text
Journal Article -
20
Abstract 5354: Prediction of OncotypeDX high risk group for chemotherapy benefit in breast cancer by deep learning analysis of hematoxylin and eosin-stained whole slide images
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Introduction: Breast cancer is the most common cancer in women, with most patients diagnosed with early-stage disease. While adjuvant therapy should be…”
Get full text
Journal Article