Search Results - "Balietti, M."
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Acetylcholinesterase inhibitors in Alzheimer's disease influence Zinc and Copper homeostasis
Published in Journal of trace elements in medicine and biology (01-09-2019)“…[Display omitted] Alzheimer's disease (AD) is the most common age-related neurodegenerative disease. An altered homeostasis of Zinc (Zn) and Copper (Cu), as…”
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My Mind Project: the effects of cognitive training for elderly—the study protocol of a prospective randomized intervention study
Published in Aging clinical and experimental research (01-06-2017)“…Background Cognitive decline and dementia represent a key problem for public health as they heavily impair social functioning and independent living. The…”
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Decreased numeric density of succinic dehydrogenase-positive mitochondria in CA1 pyramidal neurons of 3xTg-AD mice
Published in Rejuvenation research (01-04-2010)“…Alzheimer disease (AD) is associated with mitochondrial dysfunction. In this study, we investigated succinic dehydrogenase (SDH) activity in mitochondria of…”
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Structural synaptic remodeling in the perirhinal cortex of adult and old rats following object-recognition visual training
Published in Rejuvenation research (01-03-2006)“…The ultrastructural features of layer II synapses in the perirhinal cortex of adult (4- to 6-month-old) and old (25- to 27-month-old) rats exposed to a…”
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5
Perichromatin fibrils accumulation in hepatocyte nuclei reveals alterations of pre-mRNA processing during aging
Published in DNA and cell biology (01-02-2010)“…We previously described an unusual accumulation of perichromatin fibrils (PF)-the in situ form of pre-mRNA transcription and early splicing-in hepatocyte…”
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Chronic Aluminum Administration to Old Rats Results in Increased Levels of Brain Metal Ions and Enlarged Hippocampal Mossy Fibers
Published in Annals of the New York Academy of Sciences (01-06-2004)“…: The effect of chronic aluminium administration (2 g/L/6 months) was investigated in the central nervous system (CNS) of old rats. The content of Al3+, Cu2+,…”
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Role of mitochondrial deterioration in physiological and pathological brain aging
Published in Gerontology (Basel) (01-01-2004)“…Mitochondria are widely reported to occupy a unique role in modulating cell viability, senescence and death. This is consistently supported by the multiple…”
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Increased Mitochondrial and Nuclear Gene Expression of Cytochrome Oxidase Subunits I and IV in Neuronal Aging
Published in Annals of the New York Academy of Sciences (01-12-2004)“…: To assess the role of mitochondrial metabolic competence (MMC) in neuronal aging, quantitative immunohistochemistry of cytochrome oxidase (COX) subunits I…”
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Cytochrome Oxidase Activity in Hippocampal Synaptic Mitochondria during Aging: A Quantitative Cytochemical Investigation
Published in Annals of the New York Academy of Sciences (01-06-2004)“…: Synaptic mitochondria, cytochemically positive to cytochrome oxidase (COX) activity, were investigated by morphometric methods in the hippocampal dentate…”
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Decay of Mitochondrial Metabolic Competence in the Aging Cerebellum
Published in Annals of the New York Academy of Sciences (01-06-2004)“…: Cytochemically evidenced cytochrome oxidase activity was morphometrically measured in the cerebellar cortex of adult and old rats. The ratio (R) between the…”
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11
Level and distribution of microtubule-associated protein-2 (MAP2) as an index of dendritic structural dynamics
Published in Rejuvenation research (01-03-2006)“…Optical density of MAP2 immunoreactivity (OD), the ratio between the MAP2 stained area/total test area (area fraction: AF), the total length of MAP2 labeled…”
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12
Synaptic pathology in the brain cortex of old monkeys as an early alteration in senile plaque formation
Published in Rejuvenation research (01-03-2006)“…Synaptic numeric density (Nv), average size (area: S), surface density (Sv) and number of synapses/neurone (Syn/Neur) were morphometrically measured in frontal…”
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The effect of chronic aluminum(III) administration on the nervous system of aged rats: clues to understand its suggested role in Alzheimer's disease
Published in Journal of Alzheimer's disease (01-12-2003)“…The effect of chronic aluminum intake has been investigated in the brain of aged male Wistar rats to assess the potential role of the accumulation of this…”
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The effect of chronic physical exercise on succinic dehydrogenase activity in the heart muscle of old rats
Published in Biogerontology (Dordrecht) (01-03-2005)“…Succinic dehydrogenase (SDH) activity, preferentially evidenced by cytochemical methods, has been measured by computer-assisted morphometry in the heart muscle…”
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Testing mitochondrial metabolic competence by cytochrome oxidase preferential cytochemistry versus immunoreactivity of subunits I and IV
Published in Rejuvenation research (01-06-2006)“…Cytochemically evidenced COX activity was compared with levels of immunohistochemically stained mitochondrial- and nuclear-encoded subunits (CO I and CO IV) in…”
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Age-related decline in metabolic competence of small and medium-sized synaptic mitochondria
Published in Die Naturwissenschaften (01-02-2005)“…A computer-assisted morphometric investigation of cytochrome oxidase (COX) activity, selectively evidenced by preferential diaminobenzidine cytochemistry, has…”
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