Search Results - "Balian, D"

Reproducibility of semi-quantitative assessment of aortic valve calcification and valve motion on echocardiography: a small-scale study by Balian, D, Koethe, B, Mohanty, S, Daaboul, Y, Mahrokhian, S H, Frankel, J, Li, J, Kherlopian, A, Downey, B C, Wessler, B

“…Aortic stenosis (AS) is the most common degenerative valve disease in high income countries. While hemodynamic metrics are commonly used to assess severity of…”
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Interspecies scaling: predicting clearance of drugs in humans. Three different approaches by Mahmood, I, Balian, J D

“…1. The interspecies scaling approach to predict clearance in humans from animal data was tested for a wide variety of drugs. 2. Three different methods were…”
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Pharmacokinetic and Pharmacodynamic Consequences of Metabolism-Based Drug Interactions with Alprazolam, Midazolam, and Triazolam by Yuan, Rae, Flockhart, David A., Balian, John D.

“…This review was conducted to identify the current data on drug interactions with alprazolam, midazolam, and triazolam to guide practitioners in the use of…”
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The hydroxylation of omeprazole correlates with S-mephenytoin metabolism: a population study by Balian, J D, Sukhova, N, Harris, J W, Hewett, J, Pickle, L, Goldstein, J A, Woosley, R L, Flockhart, D A

“…We compared omeprazole and mephenytoin as probes for the CYP2C19 metabolic polymorphism. Single oral doses of omeprazole (20 mg) or mephenytoin (100 mg) were…”
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The pharmacokinetic principles behind scaling from preclinical results to phase I protocols by MAHMOOD, I, BALIAN, J. D

“…Extrapolation of animal data to assess pharmacokinetic parameters in humans is an important tool in drug development. Allometric scaling has many proponents,…”
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In vitro metabolic interaction studies: Experience of the Food and Drug Administration by Yuan, Rae, Parmelee, Thomas, Balian, John D., Uppoor, Ramana S., Ajayi, Funmilayo, Burnett, Alfreda, Lesko, Larry J., Marroum, Patrick

“…A total of 194 new molecular entities approved by the Food and Drug Administration between 1992 and 1997 were surveyed to determine the role of in vitro…”
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Designing and implementing procurement requirements for carbon reduction in infrastructure construction - international overview and experiences by Kadefors, Anna, Lingegård, Sofia, Uppenberg, Stefan, Alkan-Olsson, Johanna, Balian, Daniel

“…Carbon emissions emanating from infrastructure construction are substantial, and public infrastructure clients have begun to include carbon reduction goals in…”
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Interspecies scaling: predicting pharmacokinetic parameters of antiepileptic drugs in humans from animals with special emphasis on clearance by Mahmood, I, Balian, J D

“…The objective of this study was to test the interspecies-scaling approach in a series of antiepileptic drugs. Clearance, volume of distribution, and…”
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In vivo drug-drug interaction studies- A survey of all new molecular entities approved from 1987 to 1997 by Marroum, Patrick J., Uppoor, Ramana S., Parmelee, Thomas, Ajayi, Funmilayo, Burnett, Alfreda, Yuan, Rae, Svadjian, Raffi, Lesko, Lawrence J., Balian, John D.

“…Ninety‐eight new molecular entities applications approved between 1987 to 1991 (period I) and 193 applications for new molecular entities between 1992 to 1997…”
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Determination of CYP2C19 phenotype in black Americans with omeprazole: correlation with genotype by Marinac, J S, Balian, J D, Foxworth, J W, Willsie, S K, Daus, J C, Owen, R, Flockhart, D A

“…Our objective was to study omeprazole as a single-dose oral probe in the determination of CYP2C19 phenotype in black subjects and to determine the correlation…”
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Roadmap to risk evaluation and mitigation strategies (REMS) success by Balian, John D., Wherry, Janice C., Malhotra, Rachpal, Perentesis, Valerie

“…Medical safety-related risk management is a rapidly evolving and increasingly important aspect of drug approval and market longevity. To effectively meet the…”
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Interspecies scaling: A comparative study for the prediction of clearance and volume using two or more than two species by Mahmood, Iftekhar, Balian, John Dikran

“…The prediction of pharmacokinetic parameters in humans from data obtained in lower animals can be of considerable importance in the process of drug…”
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A Prospective Observational Study Assessing Home Parenteral Nutrition in Patients With Gastrointestinal Cancer: Benefits for Quality of Life by Senesse, Pierre, MD, PhD, Tadmouri, Abir, PhD, Culine, Stéphane, MD, PhD, Dufour, Patrick R., MD, Seys, Patrick, MD, Radji, Abderraouf, MD, Rotarski, Maciej, MD, Balian, Axel, MD, Chambrier, Cecile, MD, PhD

“…Abstract Context Patients with gastrointestinal cancer are at high risk for deterioration of nutrition. Home parenteral nutrition (HPN) could improve…”
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Real-Time Assessment of Myocardial Viability in the Catheterization Laboratory Using the Intracoronary Electrograms Recorded by the PTCA Guidewire in Patients With Left Ventricular Dysfunction by Petrucci, Ettore, MD, Balian, Vruyr, MD, Bocchieri, Andrea, PhD

“…Abstract Objectives This study aimed to determine whether the intracoronary electrograms (IC-EGMs) recorded using a standard percutaneous coronary intervention…”
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Metabolic drug-drug interactions: perspective from FDA medical and clinical pharmacology reviewers by Balian, J D, Rahman, A

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Clinical Relevance and Labeling of Food-Effect Bioavailability (FEB) Studies by Parekh, A., Barsamian, A., Balian, J.D., Lesko, L.

“…Clinical Pharmacology & Therapeutics (1999) 65, 174–174; doi:…”
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Hepatic Impairment (HI) Studies Submitted in New Drug Applications (NDAs) by Mehta, M., Parmelee, T., Balian, J.D., Lesko, L.

“…Clinical Pharmacology & Therapeutics (1999) 65, 129–129; doi:…”
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Equivalent therapeutic efficacy and safety of ivermectin and lindane in the treatment of human scabies by Chouela, E N, Abeldaño, A M, Pellerano, G, La Forgia, M, Papale, R M, Garsd, A, Balian, M C, Battista, V, Poggio, N

“…To compare the therapeutic efficacy and safety of ivermectin and lindane for the treatment of human scabies. Randomized, prospective, controlled, double-blind,…”
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