Search Results - "Baliakas, P"
-
1
Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: updated ERIC recommendations
Published in Leukemia (01-07-2017)Get full text
Journal Article -
2
Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?
Published in Journal of internal medicine (01-04-2016)“…The remarkable clinical heterogeneity in chronic lymphocytic leukaemia (CLL) has highlighted the need for prognostic and predictive algorithms that can be…”
Get full text
Journal Article -
3
Recurrent mutations refine prognosis in chronic lymphocytic leukemia
Published in Leukemia (01-02-2015)“…Through the European Research Initiative on chronic lymphocytic leukemia (CLL) (ERIC), we screened 3490 patients with CLL for mutations within the NOTCH1 ( n…”
Get full text
Journal Article -
4
Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2
Published in Leukemia (01-11-2013)“…Recent studies have revealed recurrent mutations of the NOTCH1 , SF3B1 and BIRC3 genes in chronic lymphocytic leukemia (CLL), especially among aggressive,…”
Get full text
Journal Article -
5
Outbreak of cutaneous zygomycosis associated with the use of adhesive tape in haematology patients
Published in The Journal of hospital infection (01-07-2012)“…Summary We report an outbreak of cutaneous Rhizopus oryzae infection associated with adhesive polyethylene tapes used to stabilize peripheral venous catheters…”
Get full text
Journal Article -
6
An Immunogenetic Signature of Ongoing Antigen Interactions in Splenic Marginal Zone Lymphoma Expressing IGHV1-204 Receptors
Published in Clinical cancer research (15-04-2016)“…Prompted by the extensive biases in the immunoglobulin (IG) gene repertoire of splenic marginal-zone lymphoma (SMZL), supporting antigen selection in SMZL…”
Get full text
Journal Article -
7
UGT2B17 expression: a novel prognostic marker within IGHV-mutated chronic lymphocytic leukemia?
Published in Haematologica (Roma) (01-02-2016)Get full text
Journal Article -
8
Selection of antigen receptors in splenic marginal-zone lymphoma: further support from the analysis of the immunoglobulin light-chain gene repertoire
Published in Leukemia (01-12-2012)Get full text
Journal Article -
9
Coexistence of trisomies of chromosomes 12 and 19 in chronic lymphocytic leukemia occurs exclusively in the rare IgG-positive variant
Published in Leukemia (01-01-2012)Get full text
Journal Article -
10
Prognostic and Predictive Implications of Cytogenetics and Genomics
Published in Hematology/oncology clinics of North America (01-08-2021)“…Chronic lymphocytic leukemia (CLL) is characterized by extreme genomic heterogeneity. Numerous recurrent genetic abnormalities are associated with dismal…”
Get full text
Journal Article -
11
Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact
Published in Blood (14-03-2019)“…Recent evidence suggests that complex karyotype (CK) defined by the presence of ≥3 chromosomal aberrations (structural and/or numerical) identified by using…”
Get full text
Journal Article -
12
Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL
Published in Blood (11-03-2021)“…Chronic lymphocytic leukemia (CLL) is characterized by the existence of subsets of patients with (quasi)identical, stereotyped B-cell receptor (BcR)…”
Get full text
Journal Article -
13
COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study
Published in Leukemia (01-12-2021)“…Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to Coronavirus disease 2019 (COVID-19) due to age, disease, and treatment-related…”
Get full text
Journal Article -
14
Somatic Exonic Deletions in RUNX1 Constitutes a Novel Recurrent Genomic Abnormality in Acute Myeloid Leukemia
Published in Clinical cancer research (01-08-2023)“…In acute myeloid leukemia (AML), somatic mutations (commonly missense, nonsense, and frameshift indels) in RUNX1 are associated with a dismal clinical outcome…”
Get full text
Journal Article -
15
The clinical phenotype of germline RUNX1 mutations in relation to the accompanying somatic variants and RUNX1 isoform expression
Published in Genes chromosomes & cancer (01-11-2023)“…Germline RUNX1 mutations lead to familial platelet disorder with associated myeloid malignancy (FPDMM), characterized by thrombocytopenia, abnormal bleeding,…”
Get full text
Journal Article -
16
Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations
Published in Blood (25-02-2016)“…Fludarabine, cyclophosphamide, and rituximab (FCR) is first-line treatment of medically fit chronic lymphocytic leukemia (CLL) patients; however, despite good…”
Get full text
Journal Article -
17
ARResT/AssignSubsets: a novel application for robust subclassification of chronic lymphocytic leukemia based on B cell receptor IG stereotypy
Published in Bioinformatics (Oxford, England) (01-12-2015)“…An ever-increasing body of evidence supports the importance of B cell receptor immunoglobulin (BcR IG) sequence restriction, alias stereotypy, in chronic…”
Get full text
Journal Article -
18
Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: a multi-center study
Published in Haematologica (Roma) (2021)“…Complex karyotype (CK) identified by chromosome-banding analysis (CBA) has shown prognostic value in chronic lymphocytic leukemia (CLL). Genomic arrays offer…”
Get full text
Journal Article -
19
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY
Published in Leukemia (01-02-2023)“…Recent evidence suggests that the prognostic impact of gene mutations in patients with chronic lymphocytic leukemia (CLL) may differ depending on the…”
Get full text
Journal Article -
20
Integrating a Polygenic Risk Score into a clinical setting would impact risk predictions in familial breast cancer
Published in Journal of medical genetics (01-02-2024)“…Low-impact genetic variants identified in population-based genetic studies are not routinely measured as part of clinical genetic testing in familial breast…”
Get more information
Journal Article