Search Results - "Bales, Brian C."

Novel intravascular tantalum oxide-based contrast agent achieves improved vascular contrast enhancement and conspicuity compared to Iopamidol in an animal multiphase CT protocol by Heimer, Maurice M., Sun, Yuxin, Grosu, Sergio, Cyran, Clemens C., Bonitatibus, Peter J., Okwelogu, Nikki, Bales, Brian C., Meyer, Dan E., Yeh, Benjamin M.

“…Background To assess thoracic vascular computed tomography (CT) contrast enhancement of a novel intravenous tantalum oxide nanoparticle contrast agent…”
Get full text

Methane Oxidation by Aqueous Osmium Tetroxide and Sodium Periodate: Inhibition of Methanol Oxidation by Methane by Osako, Takao, Watson, Eric J., Dehestani, Ahmad, Bales, Brian C., Mayer, James M.

“…Cast in a new role: Aqueous solutions of OsO4 and NaIO4 oxidize methane to methanol under very mild conditions (see scheme). The generated methanol is…”
Get full text

Radiolabeled Aminopyrazoles as Novel Isoform Selective Probes for pJNK3 Quantification by Bales, Brian C., Cotero, Victoria, Meyer, Dan E., Roberts, Jeannette C., Rodriguez-Silva, Monica, Siclovan, Tiberiu M., Chambers, Jeremy W., Rishel, Michael J.

“…The c-Jun N-terminal kinase 3 (JNK3) is a stress-activated kinase primarily expressed in the brain and implicated as an early mediator of neuronal apoptosis…”
Get full text

Fe-HBED Analogs: A Promising Class of Iron-Chelate Contrast Agents for Magnetic Resonance Imaging by Roberts, Jeannette, Polyanskaya, Tatyana, Meyer, Dan E., Luttrell, M. Todd, Johnson, Bruce F., Grimmond, Brian, Bales, Brian C., Rishel, Michael J.

“…Contrast-enhanced magnetic resonance imaging is an essential tool for disease diagnosis and management; all marketed clinical magnetic resonance imaging (MRI)…”
Get full text

In vitro and in vivo DFO-chelatable labile iron release profiles among commercially available intravenous iron nanoparticle formulations by Pai, Amy Barton, Pai, Manjunath P., Meyer, Dan E., Bales, Brian C., Cotero, Victoria E., Zheng, Nan, Jiang, Wenlei

“…Intravenous (IV) iron formulations are complex colloidal suspensions of iron oxide nanoparticles. Small changes in formulation can allow more labile iron to be…”
Get full text

Mechanistic studies on DNA damage by minor groove binding copper–phenanthroline conjugates by Bales, Brian C., Kodama, Tetsuya, Weledji, Yvonne N., Pitié, Marguerite, Meunier, Bernard, Greenberg, Marc M.

“…Copper–phenanthroline complexes oxidatively damage and cleave nucleic acids. Copper bis-phenanthroline and copper complexes of mono- and bis-phenanthroline…”
Get full text

Alkane Oxidation by Osmium Tetroxide by Bales, Brian C, Brown, Peter, Dehestani, Ahmad, Mayer, James M

“…Aqueous alkaline OsO4 at 85 °C oxidizes saturated alkanes, including primary, secondary, and tertiary C−H bonds. Isobutane affords tert-butanol in quantitative…”
Get full text

Synthesis of highly loaded and well-controlled magnetic beads via emulsion polymerization by Kniajanski, Sergei, Colborn, Robert E., Bales, Brian C., Riccobono, Orrie, Dulgar-Tulloch, Aaron J., Stein, Judith, Kandapallil, Binil I. I.

“…Superparamagnetic iron oxide (SPIO) incorporated polystyrene beads of uniform size distribution (∼170 nm) and high magnetic content (∼40%) are synthesized by…”
Get full text

Covalent Trapping of Human DNA Polymerase β by the Oxidative DNA Lesion 2-Deoxyribonolactone by DeMott, Michael S., Beyret, Ergin, Wong, Donny, Bales, Brian C., Hwang, Jae-Taeg, Greenberg, Marc M., Demple, Bruce

“…Oxidized abasic residues in DNA constitute a major class of radiation and oxidative damage. Free radical attack on the nucleotidyl C-1′ carbon yields…”
Get full text

A Minor Groove Binding Copper-Phenanthroline Conjugate Produces Direct Strand Breaks via β-Elimination of 2-Deoxyribonolactone by Bales, Brian C, Pitié, Marguerite, Meunier, Bernard, Greenberg, Marc M

“…Copper-phenanthroline complexes and their conjugates are useful reagents for studying nucleic acid interactions. Although DNA cleavage by such complexes was…”
Get full text

Estimating amounts of iron oxide from gradient echo images by Dixon, W. Thomas, Blezek, Daniel J., Lowery, Lisa A., Meyer, Dan E., Kulkarni, Amit M., Bales, Brian C., Petko, Danielle L., Foo, Thomas K.

“…Rat legs directly injected with superparamagnetic iron oxide (SPIO) were studied by dual‐echo, gradient‐echo imaging. The amount of iron injected was estimated…”
Get full text

Stoichiometric oxidations of σ-bonds: Radical and possible non-radical pathways by Mayer, James M., Mader, Elizabeth A., Roth, Justine P., Bryant, Jasmine R., Matsuo, Takashi, Dehestani, Ahmad, Bales, Brian C., Watson, Eric J., Osako, Takao, Valliant-Saunders, Karine, Lam, Wai Han, Hrovat, David A., Borden, Weston Thatcher, Davidson, Ernest R.

“…Oxidizing transition metal complexes can abstract hydrogen atoms from C H and O H bonds. Examples reviewed here include oxidations of alkylaromatics and…”
Get full text

Repair of Oxidized Abasic Sites by Exonuclease III, Endonuclease IV, and Endonuclease III by Greenberg, Marc M, Weledji, Yvonne N, Kim, Jaeseung, Bales, Brian C

“…2-Deoxyribonolactone (L) and the C4‘-oxidized abasic site (C4-AP) are produced by a variety of DNA-damaging agents. If not repaired, these lesions can be…”
Get full text

Product Studies and Laser Flash Photolysis on Alkyl Radicals Containing Two Different β-Leaving Groups Are Consonant with the Formation of an Olefin Cation Radical by Bales, Brian C, Horner, John H, Huang, Xianhai, Newcomb, Martin, Crich, David, Greenberg, Marc M

“…1-Bromo-2-methoxy-1-phenylpropan-2-yl (3) and 2-methoxy-1-phenyl-1-diphenylphosphatopropan-2-yl (4) were generated under continual photolysis from the…”
Get full text

Methane Oxidation by Aqueous Osmium Tetroxide and Sodium Periodate: Inhibition of Methanol Oxidation by Methane by Osako, Takao, Watson, Eric J., Dehestani, Ahmad, Bales, Brian C., Mayer, James M.

“…Eine ganz neue Rolle: Wässrige Lösungen von OsO4 und NaIO4 oxidieren unter sehr milden Bedingungen Methan zu Methanol. Das gebildete Methanol liegt auch nach 5…”
Get full text

Covalent Trapping of Human DNA Polymerase β by the Oxidative DNA Lesion 2-Deoxyribonolactone by Michael S. DeMott, Ergin Beyret, Donny Wong, Brian C. Bales, Jae-Taeg Hwang, Marc M. Greenberg, Bruce Demple

“…Oxidized abasic residues in DNA constitute a major class of radiation and oxidative damage. Free radical attack on the nucleotidyl C-1′ carbon yields…”
Get full text

Methane Oxidation by Aqueous Osmium Tetroxide and Sodium Periodate: Inhibition of Methanol Oxidation by Methane by Osako, Takao, Watson, Eric J., Dehestani, Ahmad, Bales, Brian C., Mayer, James M.

Get full text