Search Results - "Bale, L"

Parental Advisory: Maternal and Paternal Stress Can Impact Offspring Neurodevelopment by Chan, Jennifer C, Nugent, Bridget M., Bale, Tracy L.

“…Parental stress exposures are implicated in the risk for offspring neurodevelopmental and neuropsychiatric disorders, prompting critical examination of…”
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Prenatal Stress-Induced Increases in Placental Inflammation and Offspring Hyperactivity Are Male-Specific and Ameliorated by Maternal Antiinflammatory Treatment by Bronson, Stefanie L, Bale, Tracy L

“…Adverse experiences during gestation such as maternal stress and infection are known risk factors for neurodevelopmental disorders, including schizophrenia,…”
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The Placenta as a Mediator of Stress Effects on Neurodevelopmental Reprogramming by Bronson, Stefanie L, Bale, Tracy L

“…Adversity experienced during gestation is a predictor of lifetime neuropsychiatric disease susceptibility. Specifically, maternal stress during pregnancy…”
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Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress by Rodgers, Ali B., Morgan, Christopher P., Leu, N. Adrian, Bale, Tracy L.

“…Epigenetic signatures in germ cells, capable of both responding to the parental environment and shaping offspring neurodevelopment, are uniquely positioned to…”
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Sex-Specific Programming of Offspring Emotionality after Stress Early in Pregnancy by Mueller, Bridget R, Bale, Tracy L

“…Prenatal stress is associated with an increased vulnerability to neurodevelopmental disorders, including autism and schizophrenia. To determine the critical…”
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Maternal High-Fat Diet Effects on Third-Generation Female Body Size via the Paternal Lineage by Dunn, Gregory A, Bale, Tracy L

“…Maternal high-fat diet results in increased body size in third-generation female offspring through the paternal line that may be due to programming of…”
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Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation by Rodgers, Ali B, Morgan, Christopher P, Bronson, Stefanie L, Revello, Sonia, Bale, Tracy L

“…Neuropsychiatric disease frequently presents with an underlying hyporeactivity or hyperreactivity of the HPA stress axis, suggesting an exceptional…”
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Targeted placental deletion of OGT recapitulates the prenatal stress phenotype including hypothalamic mitochondrial dysfunction by Howerton, Christopher L., Bale, Tracy L.

“…Maternal stress is a key risk factor in neurodevelopmental disorders, which often have a sex bias in severity and prevalence. We previously identified O…”
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Maternal High-Fat Diet Promotes Body Length Increases and Insulin Insensitivity in Second-Generation Mice by Dunn, Gregory A, Bale, Tracy L

“…Maternal obesity and diet consumption during pregnancy have been linked to offspring adiposity, cardiovascular disease, and impaired glucose metabolism…”
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The maternal vaginal microbiome partially mediates the effects of prenatal stress on offspring gut and hypothalamus by Jašarević, Eldin, Howard, Christopher D., Morrison, Kathleen, Misic, Ana, Weinkopff, Tiffany, Scott, Phillip, Hunter, Christopher, Beiting, Daniel, Bale, Tracy L.

“…Early prenatal stress disrupts maternal-to-offspring microbiota transmission and has lasting effects on metabolism, physiology, cognition, and behavior in male…”
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Stress during pregnancy alters temporal and spatial dynamics of the maternal and offspring microbiome in a sex-specific manner by Jašarević, Eldin, Howard, Christopher D., Misic, Ana M., Beiting, Daniel P., Bale, Tracy L.

“…The microbiome is a regulator of host immunity, metabolism, neurodevelopment, and behavior. During early life, bacterial communities within maternal gut and…”
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CRF and CRF receptors: Role in stress responsivity and other behaviors by BALER, Tracy L, VALE, Wylie W

“…Since corticotropin-releasing factor (CRF) was first characterized, a growing family of ligands and receptors has evolved. The mammalian family members include…”
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Placental H3K27me3 establishes female resilience to prenatal insults by Nugent, Bridget M., O’Donnell, Carly M., Epperson, C. Neill, Bale, Tracy L.

“…Although sex biases in disease presentation are well documented, the mechanisms mediating vulnerability or resilience to diseases are unknown. In utero insults…”
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O-GlcNAc transferase (OGT) as a placental biomarker of maternal stress and reprogramming of CNS gene transcription in development by Howerton, Christopher L., Morgan, Christopher P., Fischer, David B., Bale, Tracy L.

“…Maternal stress is a key risk factor for neurodevelopmental disorders, including schizophrenia and autism, which often exhibit a sex bias in rates of…”
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The critical importance of basic animal research for neuropsychiatric disorders by Bale, Tracy L, Abel, Ted, Akil, Huda, Carlezon, Jr, William A, Moghaddam, Bita, Nestler, Eric J, Ressler, Kerry J, Thompson, Scott M

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Reproductive tract extracellular vesicles are sufficient to transmit intergenerational stress and program neurodevelopment by Chan, Jennifer C., Morgan, Christopher P., Adrian Leu, N., Shetty, Amol, Cisse, Yasmine M., Nugent, Bridget M., Morrison, Kathleen E., Jašarević, Eldin, Huang, Weiliang, Kanyuch, Nickole, Rodgers, Ali B., Bhanu, Natarajan V., Berger, Dara S., Garcia, Benjamin A., Ament, Seth, Kane, Maureen, Neill Epperson, C., Bale, Tracy L.

“…Extracellular vesicles (EVs) are a unique mode of intercellular communication capable of incredible specificity in transmitting signals involved in cellular…”
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Stress sensitivity and the development of affective disorders by Bale, Tracy L.

“…Depressive disorders are the most common form of mental illness in America, affecting females twice as often as males. The great variability of symptoms and…”
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Extracellular vesicles are dynamic regulators of maternal glucose homeostasis during pregnancy by Zierden, Hannah C., Marx-Rattner, Ruth, Rock, Kylie D., Montgomery, Kristen R., Anastasiadis, Pavlos, Folts, Lillian, Bale, Tracy L.

“…Homeostatic regulation of the maternal milieu during pregnancy is critical for maternal and fetal health. The placenta facilitates critical communication…”
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It's the fiber, not the fat: significant effects of dietary challenge on the gut microbiome by Morrison, Kathleen E, Jašarević, Eldin, Howard, Christopher D, Bale, Tracy L

“…Dietary effects on the gut microbiome play key roles in the pathophysiology of inflammatory disorders, metabolic syndrome, obesity, and behavioral…”
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Prenatal Programming of Mental Illness: Current Understanding of Relationship and Mechanisms by Kim, Deborah R., Bale, Tracy L., Epperson, C. Neill

“…The British epidemiologist Dr. David J. Barker documented the relationship between infant birth weight and later onset of hypertension, coronary heart disease,…”
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