Search Results - "Baldwin III, W M"
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An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell–suppressive function and therapeutic efficacy
Published in Mucosal immunology (01-01-2016)“…Foxp3-expressing regulatory T cells (Tregs) are central regulators of immune homeostasis and tolerance. As it has been suggested that proper Treg function is…”
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2
The Spleen Is the Major Source of Antidonor Antibody‐Secreting Cells in Murine Heart Allograft Recipients
Published in American journal of transplantation (01-07-2012)“…Antibody‐mediated allograft rejection is an increasingly recognized problem in clinical transplantation. However, the primary location of donor‐specific…”
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3
Platelets Influence Vascularized Organ Transplants from Start to Finish
Published in American journal of transplantation (01-01-2009)“…This review relates the basic functions of platelets to specific aspects of organ allograft rejection. Platelet activation can occur in the donor or recipient…”
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4
Antibody‐Mediated Rejection of Single Class I MHC‐Disparate Cardiac Allografts
Published in American journal of transplantation (01-08-2012)“…Murine CCR5−/− recipients produce high titers of antibody to complete MHC‐mismatched heart and renal allografts. To study mechanisms of class I MHC…”
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5
NK Cells: New Partners in Antibody‐Triggered Chronic Rejection
Published in American journal of transplantation (01-02-2012)“…NK cells have a surprising new role in transplant vasculopathy by partnering with donor‐specific antibodies. See article by Hirohashi et al on page 313…”
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6
Of Mice and Men: Terminal Complement Inhibition With Anti‐C5 Monoclonal Antibodies
Published in American journal of transplantation (01-11-2011)“…The author provides perspective on clinical application of C5‐specific antibody therapy for terminal complement inhibition in kidney transplantation. See…”
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7
B Cells and Plasma Cells in Coronaries of Chronically Rejected Cardiac Transplants
Published in Transplantation (15-05-2010)“…BACKGROUND.: Previously, we reported that transcripts of immunoglobulins were increased in coronary arteries dissected from cardiac transplants with…”
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8
Treatment with riboflavin and ultraviolet light prevents alloimmunization to platelet transfusions and cardiac transplants
Published in Transplantation (15-11-2007)“…Functional leukocytes in blood transfusions can cause alloimmunization. Previous studies have shown that exposure of platelet concentrates to riboflavin and…”
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9
The Involvement of FcR Mechanisms in Antibody-Mediated Rejection
Published in Transplantation (27-11-2007)“…Antibody-mediated rejection is characterized by macrophage margination against vascular endothelium. The potential interactions triggered by antibodies between…”
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10
Lymphatic Injury and Regeneration in Cardiac Allografts
Published in Transplantation (15-03-2010)“…Severed donor heart lymphatics are not anastomosed to recipient lymphatics in cardiac transplantation. We evaluated the effects of cellular infiltrates of T…”
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11
A human suppressor T-cell factor that inhibits T-cell replication by interaction with the IgM-Fc receptor (CD7)
Published in Human immunology (01-06-1989)“…We have previously described the induction of human suppressor T cells from fresh peripheral blood lymphocytes of a kidney transplant recipient by in vitro…”
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12
Immunopathological abnormalities in the normal skin of patients with rheumatoid arthritis in relation to clinical and serological findings: a one year follow up study
Published in Annals of the rheumatic diseases (01-03-1987)“…Fifty two patients with seropositive rheumatoid arthritis (RA) were studied over a period of one year to investigate possible relationships among changes of…”
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13
Association of rheumatoid factors in renal transplant recipients with cytomegalovirus infection and not with rejection
Published in Transplantation (01-05-1987)“…Because rheumatoid factors (RF) were detected in the circulation of the majority of early renal transplant recipients and could be eluted from rejected…”
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14
Innate Immune Responses to Transplants: A Significant Variable with Cadaver Donors
Published in Immunity (01-04-2001)“…Over the past several decades, advances in the study of T cell biology have led to numerous experimental protocols and strategies to induce transplantation…”
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15
Anti-Human Leukocyte Antigen Antibodies, Vascular C4d Deposition and Increased Soluble C4d in Broncho-Alveolar Lavage of Lung Allografts
Published in Transplantation (27-07-2008)“…The hallmark of humoral rejection is the presence of subendothelial C4d in the allograft. A simultaneous determination of vascular C4d with soluble C4d in…”
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16
Passive transfer of alloantibodies restores acute cardiac rejection in IgKO MICE
Published in Transplantation (27-03-2001)“…Alloantibody is an intrinsic component of the immune response to organ transplants. Although alloantibodies have been correlated with decreased graft survival,…”
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17
Antibody and complement mediated injury in transplants following sensitization by allogeneic blood transfusion
Published in Transplantation (15-10-2006)“…Many patients on the waiting list for transplants are sensitized from previous blood transfusions, pregnancy, or transplants. We investigated the role of…”
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18
Perivascular deposits of IgM in the skin of transplant recipients during active cytomegalovirus infections. Correlation with IgM rheumatoid factors and IgM immune complexes
Published in Transplantation (01-10-1987)“…Skin biopsies from 30 renal transplant patients were investigated for cellular infiltrates and deposits of IgM, IgA, IgG, C3, and C5-9 neoantigen. Granular…”
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19
Terminal complement components mediate release of von Willebrand factor and adhesion of platelets in arteries of allografts
Published in Transplantation (15-02-2005)“…Both humoral and cellular immune responses can cause arterial injury in organ transplants, but the manifestations of these different inflammatory mechanisms…”
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20
Complement deposition in early cardiac transplant biopsies is associated with ischemic injury and subsequent rejection episodes
Published in Transplantation (27-09-1999)“…Prolonged warm or cold ischemia is associated with poor survival of cardiac transplants, and ischemic changes in early posttransplantation endomyocardial…”
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