Search Results - "Baldwin, W M"

An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell–suppressive function and therapeutic efficacy by Do, J-s, Visperas, A, Sanogo, Y O, Bechtel, J J, Dvorina, N, Kim, S, Jang, E, Stohlman, S A, Shen, B, Fairchild, R L, Baldwin III, W M, Vignali, D A A, Min, B

“…Foxp3-expressing regulatory T cells (Tregs) are central regulators of immune homeostasis and tolerance. As it has been suggested that proper Treg function is…”
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Facile Amide Bond Formation with TCFH–NMI in an Organic Laboratory Course by M. Baldwin, Oliver W., Conrad-Marut, Linden H., Beutner, Gregory L., Vosburg, David A.

“…A new undergraduate organic laboratory experiment has been developed for amide bond formation between biorenewable 2-furoic acid and either of two substituted…”
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IL‐15 Induces Alloreactive CD28− Memory CD8 T Cell Proliferation and CTLA4‐Ig Resistant Memory CD8 T Cell Activation by Traitanon, O., Gorbachev, A., Bechtel, J. J., Keslar, K. S., Baldwin, W. M., Poggio, E. D., Fairchild, R. L.

“…The presence of CD28− memory CD8 T cells in the peripheral blood of renal transplant patients is a risk factor for graft rejection and resistance to CTLA‐4Ig…”
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The Spleen Is the Major Source of Antidonor Antibody‐Secreting Cells in Murine Heart Allograft Recipients by Sicard, A., Phares, T. W., Yu, H., Fan, R., Baldwin III, W. M., Fairchild, R. L., Valujskikh, A.

“…Antibody‐mediated allograft rejection is an increasingly recognized problem in clinical transplantation. However, the primary location of donor‐specific…”
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Platelets Influence Vascularized Organ Transplants from Start to Finish by Kirk, A. D., Morrell, C. N., Baldwin, III, W. M.

“…This review relates the basic functions of platelets to specific aspects of organ allograft rejection. Platelet activation can occur in the donor or recipient…”
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Platelets an Inflammatory Force in Transplantation by Morrell, C. N., Sun, H., Swaim, A. M., Baldwin, W. M.

“…Platelet interactions with dendritic cells, T cells and B cells have been best studied in vasculitis and atherosclerosis, but similar mechanisms may contribute…”
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Complement Dependence of Murine Costimulatory Blockade‐Resistant Cellular Cardiac Allograft Rejection by Chun, N., Fairchild, R. L., Li, Y., Liu, J., Zhang, M., Baldwin, W. M., Heeger, P. S.

“…Building on studies showing that ischemia–reperfusion‐(I/R)‐injury is complement dependent, we tested links among complement activation,…”
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Graft‐Derived CCL2 Increases Graft Injury During Antibody‐Mediated Rejection of Cardiac Allografts by Abe, T., Su, C. A., Iida, S., Baldwin, W. M., Nonomura, N., Takahara, S., Fairchild, R. L.

“…The pathogenic role of macrophages in antibody‐mediated rejection (AMR) remains unclear. Monocyte chemoattractant protein‐1 (MCP‐1/CCL2) is a potent…”
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Endogenous Memory CD8 T Cells Are Activated Within Cardiac Allografts Without Mediating Rejection by Setoguchi, K., Hattori, Y., Iida, S., Baldwin, W. M., Fairchild, R. L.

“…Endogenous memory CD8 T cells infiltrate MHC‐mismatched cardiac allografts within 12–24 h posttransplant in mice and are activated to proliferate and produce…”
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Antibody‐Mediated Rejection of Single Class I MHC‐Disparate Cardiac Allografts by Hattori, Y., Bucy, R. P., Kubota, Y., Baldwin III, W. M., Fairchild, R. L.

“…Murine CCR5−/− recipients produce high titers of antibody to complete MHC‐mismatched heart and renal allografts. To study mechanisms of class I MHC…”
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LFA‐1 Antagonism Inhibits Early Infiltration of Endogenous Memory CD8 T Cells into Cardiac Allografts and Donor‐Reactive T Cell Priming by Setoguchi, K., Schenk, A. D., Ishii, D., Hattori, Y., Baldwin, W. M., Tanabe, K., Fairchild, R. L.

“…Alloreactive memory T cells are present in virtually all transplant recipients due to prior sensitization or heterologous immunity and mediate injury…”
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Parental recall, attachment relating and self-attacking/self-reassurance: Their relationship with depression by Irons, C., Gilbert, P., Baldwin, M.W., Baccus, J. R., Palmer, M.

“…Objectives. When things go wrong for people they can become self‐critical or focus on positive, reassuring aspects of the self. This study explored the…”
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Recent Progress and New Perspectives in Studying T Cell Responses to Allografts by Valujskikh, A., Baldwin, W. M., Fairchild, R. L.

“…Studies in the past decade advanced our understanding of the development, execution and regulation of T‐cell‐mediated allograft rejection. This review outlines…”
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Synergistic Deposition of C4d by Complement‐Activating and Non‐activating Antibodies in Cardiac Transplants by Murata, K., Fox‐Talbot, K., Qian, Z., Takahashi, K., Stahl, G. L., Baldwin, W. M., Wasowska, B. A.

“…The role of non‐complement‐activating alloantibodies in humoral graft rejection is unclear. We hypothesized that the non‐complement‐activating alloantibodies…”
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B Cell Activating Factor (BAFF) and a Proliferation Inducing Ligand (APRIL) Mediate CD40‐Independent Help by Memory CD4 T Cells by Gorbacheva, V., Ayasoufi, K., Fan, R., Baldwin, W. M., Valujskikh, A.

“…Donor‐reactive memory T cells undermine organ transplant survival and are poorly controlled by immunosuppression or costimulatory blockade. Memory CD4 T cells…”
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Antibody‐Mediated Rejection—An Ounce of Prevention Is Worth a Pound of Cure by Bradley, J. A., Baldwin, W. M., Bingaman, A., Ellenrieder, C., Gebel, H. M., Glotz, D., Kirk, A. D.

“…The presence of preformed, donor‐specific alloantibodies inpatients undergoing renal transplantation is associated with a high risk of hyperacute and acute…”
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Strategically Altering the Balance of Macrophage Subpopulations to Inhibit Chronic Rejection by Baldwin, W. M., Morelli, A. E.

“…Wu and colleagues (page 2563) report that treatment with oxidized ATP differentially inhibits the function of macrophage subpopulations and decreases intimal…”
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Anti‐huCD20 Antibody Therapy for Antibody‐Mediated Rejection of Renal Allografts in a Mouse Model by Abe, T., Ishii, D., Gorbacheva, V., Kohei, N., Tsuda, H., Tanaka, T., Dvorina, N., Nonomura, N., Takahara, S., Valujskikh, A., Baldwin, W. M., Fairchild, R. L.

“…We have reported that B6.CCR5−/− mice reject renal allografts with high serum donor‐specific antibody (DSA) titers and marked C4d deposition in grafts,…”
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Acute and Chronic Rejection: Compartmentalization and Kinetics of Counterbalancing Signals in Cardiac Transplants by Kaul, A. M. K., Goparaju, S., Dvorina, N., Iida, S., Keslar, K. S., de la Motte, C. A., Valujskikh, A., Fairchild, R. L., Baldwin, W. M.

“…Acute and chronic rejection impact distinct compartments of cardiac allografts. Intramyocardial mononuclear cell infiltrates define acute rejection, whereas…”
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Of Mice and Men: Terminal Complement Inhibition With Anti‐C5 Monoclonal Antibodies by Woodle, E. S., Baldwin III, W. M.

“…The author provides perspective on clinical application of C5‐specific antibody therapy for terminal complement inhibition in kidney transplantation. See…”
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