Search Results - "Baldwin, RL"

How Hofmeister ion interactions affect protein stability by Baldwin, R.L.

“…Model compound studies in the literature show how Hofmeister ion interactions affect protein stability. Although model compound results are typically obtained…”
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Characterization of a normalized cDNA library from bovine intestinal muscle and epithelial tissues by Baumann, R.G, Baldwin, R.L, Van Tassell, C.P, Sonstegard, T.S, Matukumalli, L.K

“…Tissue-specific cDNA library sequences (expressed sequence tags, or EST) yield a detailed snapshot of gene expression and are useful in developing…”
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Improved survival in women with BRCA‐associated ovarian carcinoma by Cass, Ilana, Baldwin, Rae Lynn, Varkey, Taz, Moslehi, Roxana, Narod, Steven A., Karlan, Beth Y.

“…BACKGROUND The objective of this study was to determine the clinical characteristics, treatment response, and frequency of p53 overexpression in Ashkenazi…”
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Polyproline II Structure in a Sequence of Seven Alanine Residues by Shi, Zhengshuang, Olson, C. Anders, Rose, George D., Baldwin, Robert L., Kallenbach, Neville R.

“…A sequence of seven alanine residues-too short to form an α-helix and whose side chains do not interact with each other-is a particularly simple model for…”
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In search of the energetic role of peptide hydrogen bonds by Baldwin, Robert L

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Is protein folding hierarchic? I. Local structure and peptide folding by Baldwin, Robert L., Rose, George D.

“…The folding reactions of some small proteins show clear evidence of a hierarchic process, whereas others, lacking detectable intermediates, do not…”
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Is protein folding hierarchic? II. Folding intermediates and transition states by Baldwin, Robert L., Rose, George D.

“…The folding reactions of some small proteins show clear evidence of a hierarchic process, whereas others, lacking detectable intermediates, do not. Evidence…”
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Origin of the Neighboring Residue Effect on Peptide Backbone Conformation by Avbelj, Franc, Baldwin, Robert L.

“…Unfolded peptides in water have some residual structure that may be important in the folding process, and the nature of the residual structure is currently of…”
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Mechanism of Helix Induction by Trifluoroethanol:  A Framework for Extrapolating the Helix-Forming Properties of Peptides from Trifluoroethanol/Water Mixtures Back to Water by Luo, Peizhi, Baldwin, Robert L

“…To establish a framework for extrapolating the helix-forming properties of peptides from TFE/H2O mixtures (TFE = 2,2,2-trifluoroethanol) back to water, the…”
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Intrinsic Backbone Preferences Are Fully Present in Blocked Amino Acids by Avbelj, Franc, Grdadolnik, Simona Golic, Grdadolnik, Joze, Baldwin, Robert L.

“…The preferences of amino acid residues for Φ,ψ backbone angles vary strikingly among the amino acids, as shown by the backbone angle Φ found from…”
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Astrocyte-specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures by Uhlmann, Erik J., Wong, Michael, Baldwin, Rebecca L., Bajenaru, M. Livia, Onda, Hiroaki, Kwiatkowski, David J., Yamada, Kelvin, Gutmann, David H.

“…Persons affected with tuberous sclerosis complex (TSC) develop a wide range of neurological abnormalities including aberrant neuronal migration and seizures…”
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Role of Backbone Solvation and Electrostatics in Generating Preferred Peptide Backbone Conformations: Distributions of Phi by Avbelj, Franc, Baldwin, Robert L.

“…The "coil library," consisting of the $\phi,\>\psi$ values of residues outside secondary structure in high-resolution protein structures, has chiefly the…”
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Prognostic DNA Methylation Biomarkers in Ovarian Cancer by WEI, Susan H, BALCH, Curtis, KARLAN, Beth Y, GIFFORD, Gillian, BROWN, Robert, KIM, Sun, HUANG, Tim H-M, NEPHEW, Kenneth P, PAIK, Henry H, KIM, Yoo-Sung, BALDWIN, Rae Lynn, LIYANARACHCHI, Sandya, LANG LI, ZAILONG WANG, WAN, Joseph C, DAVULURI, Ramana V

“…Purpose: Aberrant DNA methylation, now recognized as a contributing factor to neoplasia, often shows definitive gene/sequence preferences unique to specific…”
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BRCA1 promoter region hypermethylation in ovarian carcinoma : A population-based study by BALDWIN, Rae Lynn, NEMETH, Elizabeta, HANG TRAN, SHVARTSMAN, Hyun, CASS, Ilana, NAROD, Steven, KARLAN, Beth Y

“…There is a clear association between germ-line BRCA1 mutations and inherited ovarian cancer; however, the association between BRCA1 mutations and sporadic…”
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Limited validity of group additivity for the folding energetics of the peptide group by Avbelj, Franc, Baldwin, Robert L.

“…The principle of group additivity is a standard feature of analyses of the energetics of protein folding, but it is known that it may not always be valid for…”
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Protein Chemical Shifts Arising from α-Helices and β-Sheets Depend on Solvent Exposure by Avbelj, Franc, Kocjan, Darko, Baldwin, Robert L.

“…The NMR chemical shifts of certain atomic nuclei in proteins (1Hα,13Cαand13Cβ) depend sensitively on whether or not the amino acid residue is part of a…”
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Sulfate anion stabilization of native ribonuclease A both by anion binding and by the Hofmeister effect by Ramos, Carlos H.I., Baldwin, Robert L.

“…Data are reported for Tm, the temperature midpoint of the thermal unfolding curve, of ribonuclease A, versus pH (range 2–9) and salt concentration (range 0–1…”
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Comparative hybridization of an array of 21 500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas by Schummer, Michèl, Ng, WaiLap V, Bumgarner, Roger E, Nelson, Peter S, Schummer, Bernhard, Bednarski, David W, Hassell, Laurie, Baldwin, Rae Lynn, Karlan, Beth Y, Hood, Leroy

“…Comparative hybridization of cDNA arrays is a powerful tool for the measurement of differences in gene expression between two or more tissues. We optimized…”
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Circular Dichroism Spectra of Short, Fixed-Nucleus Alanine Helices by Chin, Der-Hang, Woody, Robert W., Rohl, Carol A., Baldwin, Robert L.

“…Very short alanine peptide helices can be studied in a fixed-nucleus, helix-forming system [Siedlicka, M., Goch, G., Ejchart, A., Sticht, H. & Bierzynski, A…”
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Milk production of dairy cows fed differing concentrations of rumen-degraded protein by Kalscheur, K F, Baldwin, 6th, R L, Glenn, B P, Kohn, R A

“…Thirty-two multiparous and 16 primiparous Holstein cows in midlactation averaging 126 d in milk were used to determine the effects of rumen-degraded protein…”
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