Search Results - "Baldwin, R Mitchell"

Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy by Guo, Huishan, Chitiprolu, Maneka, Roncevic, Luc, Javalet, Charlotte, Hemming, Fiona J., Trung, My Tran, Meng, Lingrui, Latreille, Elyse, Tanese de Souza, Christiano, McCulloch, Danielle, Baldwin, R. Mitchell, Auer, Rebecca, Côté, Jocelyn, Russell, Ryan Charles, Sadoul, Rémy, Gibbings, Derrick

“…Autophagy and autophagy-related genes (Atg) have been attributed prominent roles in tumorigenesis, tumor growth, and metastasis. Extracellular vesicles called…”
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Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression by Baldwin, R Mitchell, Haghandish, Nasim, Daneshmand, Manijeh, Amin, Shahrier, Paris, Geneviève, Falls, Theresa J, Bell, John C, Islam, Shahidul, Côté, Jocelyn

“…Recent evidence points to the protein arginine methyltransferase (PRMT) family of enzymes playing critical roles in cancer. PRMT7 has been identified in…”
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Arginine methyltransferases as novel therapeutic targets for breast cancer by Morettin, Alan, Baldwin, R Mitchell, Côté, Jocelyn

“…Breast cancer is the most commonly diagnosed female cancer in the world. Though therapeutic treatments are available to treat breast cancer and in some…”
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Tudor Domain Containing Protein 3 Promotes Tumorigenesis and Invasive Capacity of Breast Cancer Cells by Morettin, Alan, Paris, Geneviève, Bouzid, Younes, Baldwin, R. Mitchell, Falls, Theresa J., Bell, John C., Côté, Jocelyn

“…Tudor domain containing protein 3 (TDRD3) is a modular protein identified based on its ability to recognize methylated arginine motifs through its Tudor…”
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Transgenic overexpression of IGF-II induces spontaneous lung tumors: a model for human lung adenocarcinoma by MOOREHEAD, Roger A, SANCHEZ, Otto H, BALDWIN, R. Mitchell, KHOKHA, Rama

“…Elevated levels of insulin-like growth factor (IGF)-II are associated with a poor prognosis in human pulmonary adenocarcinoma; however, a causal role for…”
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PRMT7 methylates eukaryotic translation initiation factor 2α and regulates its role in stress granule formation by Haghandish, Nasim, Baldwin, R Mitchell, Morettin, Alan, Dawit, Haben Tesfu, Adhikary, Hemanta, Masson, Jean-Yves, Mazroui, Rachid, Trinkle-Mulcahy, Laura, Côté, Jocelyn

“…Protein arginine methyltransferases (PRMTs) are a family of enzymes that modify proteins by methylating the guanidino nitrogen atoms of arginine residues to…”
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Coordination of glioblastoma cell motility by PKCι by Baldwin, R Mitchell, Barrett, Gordon M, Parolin, Doris A E, Gillies, Jana K, Paget, Judith A, Lavictoire, Sylvie J, Gray, Douglas A, Lorimer, Ian A J

“…Glioblastoma is one of the deadliest forms of cancer, in part because of its highly invasive nature. The tumor suppressor PTEN is frequently mutated in…”
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Alternatively spliced protein arginine methyltransferase 1 isoform PRMT1v2 promotes the survival and invasiveness of breast cancer cells by Baldwin, R. Mitchell, Morettin, Alan, Paris, Genevieve, Goulet, Isabelle, Côté, Jocelyn

“…Protein arginine methylation is catalyzed by protein arginine methyltransferases (PRMTs) and plays an important role in many cellular processes. Aberrant PRMT…”
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RNA binding protein RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells by Bondy-Chorney, Emma, Baldwin, R. Mitchell, Didillon, Andréanne, Chabot, Benoît, Jasmin, Bernard J., Côté, Jocelyn

“…Aberrant expression of Protein Arginine Methyltransferases (PRMTs) has been observed in several cancer types, including breast cancer. We previously reported…”
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Activation of p38MAPK contributes to expanded polyglutamine-induced cytotoxicity by Tsirigotis, Maria, Baldwin, R Mitchell, Tang, Matthew Y, Lorimer, Ian A J, Gray, Douglas A

“…The signaling pathways that may modulate the pathogenesis of diseases induced by expanded polyglutamine proteins are not well understood. Herein we demonstrate…”
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Identification of the PRMT1v1 and PRMT1v2 specific interactomes by quantitative mass spectrometry in breast cancer cells by Baldwin, R. Mitchell, Bejide, Margaret, Trinkle-Mulcahy, Laura, Côté, Jocelyn

“…Arginine methylation is catalyzed by a family of enzymes called protein arginine methyltransferases (PRMTs). The PRMT1 gene generates at least seven distinct…”
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Coordination of glioblastoma cell motility by PKCi by Baldwin, R Mitchell, Barrett, Gordon M, Parolin, Doris AE, Gillies, Jana K, Paget, Judith A, Lavictoire, Sylvie J, Gray, Douglas A, Lorimer, Ian AJ

“…Glioblastoma is one of the deadliest forms of cancer, in part because of its highly invasive nature. The tumor suppressor PTEN is frequently mutated in…”
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Role of PRMTs in cancer: Could minor isoforms be leaving a mark? by Baldwin, R Mitchell, Morettin, Alan, Côté, Jocelyn

“…Protein arginine methyltransferases(PRMTs) catalyze the methylation of a variety of protein substrates, many of which have been linked to the development,…”
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Developing habitat models for waterbirds in urban wetlands: a log-linear approach by Pearce, Cheryl M, Green, Milford B, Baldwin, Mitchell R

“…Up to 95% of wetlands in southwestern Ontario, Canada, have been drained and converted to other land uses since the mid-1800s. Remaining wetlands now exist…”
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Atg5 Disassociates the V 1 V 0 -ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy by Guo, Huishan, Chitiprolu, Maneka, Roncevic, Luc, Javalet, Charlotte, Hemming, Fiona J, Trung, My Tran, Meng, Lingrui, Latreille, Elyse, Tanese de Souza, Christiano, McCulloch, Danielle, Baldwin, R Mitchell, Auer, Rebecca, Côté, Jocelyn, Russell, Ryan Charles, Sadoul, Rémy, Gibbings, Derrick

“…Autophagy and autophagy-related genes (Atg) have been attributed prominent roles in tumorigenesis, tumor growth, and metastasis. Extracellular vesicles called…”
Get full text

Coordination of glioblastoma cell motility by PKC? by Baldwin, R Mitchell, Barrett, Gordon M, Parolin, Doris AE, Gillies, Jana K, Paget, Judith A, Lavictoire, Sylvie J, Gray, Douglas A, Lorimer, Ian AJ

“…Background Glioblastoma is one of the deadliest forms of cancer, in part because of its highly invasive nature. The tumor suppressor PTEN is frequently mutated…”
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The role of atypical protein kinase C iota in glioblastoma multiforme by Baldwin, R. Mitchell

“…Glioblastoma multiforme is the most aggressive form of primary brain tumour occurring in adults. Despite aggressive multimodal therapy which includes surgery,…”
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