Search Results - "Baldwin, Nicole E."
-
1
mTORC1 links pathology in experimental models of Still’s disease and macrophage activation syndrome
Published in Nature communications (28-11-2022)“…Still’s disease is a severe inflammatory syndrome characterized by fever, skin rash and arthritis affecting children and adults. Patients with Still’s disease…”
Get full text
Journal Article -
2
Breaking the paradigm: Dr Insight empowers signature-free, enhanced drug repurposing
Published in Bioinformatics (Oxford, England) (15-08-2019)“…Transcriptome-based computational drug repurposing has attracted considerable interest by bringing about faster and more cost-effective drug discovery…”
Get full text
Journal Article -
3
Phantom: investigating heterogeneous gene sets in time-course data
Published in Bioinformatics (Oxford, England) (15-09-2017)“…Gene set analysis is a powerful tool to study the coordinative change of time-course data. However, most existing methods only model the overall change of a…”
Get full text
Journal Article -
4
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function
Published in Nature genetics (01-03-2005)“…Patterns of gene expression in the central nervous system are highly variable and heritable. This genetic variation among normal individuals leads to…”
Get full text
Journal Article -
5
Computational, integrative, and comparative methods for the elucidation of genetic coexpression networks
Published in Journal of biomedicine & biotechnology (30-06-2005)“…Gene expression microarray data can be used for the assembly of genetic coexpression network graphs. Using mRNA samples obtained from recombinant inbred Mus…”
Get full text
Journal Article -
6
Two "wild-type" variants of Escherichia coli sigma(70): context-dependent effects of the identity of amino acid 149
Published in Journal of bacteriology (01-02-2002)“…The identity of amino acid 149 of Escherichia coli sigma(70) has been reported variably as either arginine or aspartic acid. We show that the behavior of both…”
Get full text
Journal Article -
7
Genome-Scale Computational Approaches to Memory-Intensive Applications in Systems Biology
Published in ACM/IEEE SC 2005 Conference (SC'05) (12-11-2005)“…Graph-theoretical approaches to biological network analysis have proven to be effective for small networks but are computationally infeasible for comprehensive…”
Get full text
Conference Proceeding -
8
Isolation and characterization of mutations in region 1.2 of Escherichia coli σ 70
Published in Molecular microbiology (01-10-2001)“…Eubacterial RNA polymerase uses the sigma (σ) subunit for recognition of and transcription initiation from promoter DNA sequences. One family of σ factors…”
Get full text
Journal Article -
9
Isolation and characterization of mutations in region 1.2 of Escherichia coliσ70
Published in Molecular microbiology (01-10-2001)“…Eubacterial RNA polymerase uses the sigma (σ) subunit for recognition of and transcription initiation from promoter DNA sequences. One family of σ factors…”
Get full text
Journal Article -
10
Isolation and characterization of mutations in region 1.2 of Escherichia coli sigma(70)
Published in Molecular microbiology (01-10-2001)Get full text
Journal Article -
11
Two “Wild-Type” Variants of Escherichia coli σ 70 : Context-Dependent Effects of the Identity of Amino Acid 149
Published in Journal of bacteriology (15-02-2002)“…ABSTRACT The identity of amino acid 149 of Escherichia coli σ 70 has been reported variably as either arginine or aspartic acid. We show that the behavior of…”
Get full text
Journal Article -
12
Two “Wild-Type” Variants of Escherichia coli σ70: Context-Dependent Effects of the Identity of Amino Acid 149
Published in Journal of Bacteriology (15-02-2002)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
13
Two "wild type" variants of Escherichia coli sigma70: Context-dependent effects of the identity of amino acid 149
Published in Journal of bacteriology (01-02-2002)“…The identity of amino acid 149 of Escherichia coli sigma(70) has been reported variably as either arginine or aspartic acid. We show that the behavior of both…”
Get full text
Journal Article -
14
Two “Wild-Type” Variants of Escherichia coli ςsgr;70: Context-Dependent Effects of the Identity of Amino Acid 149
Published in Journal of bacteriology (01-02-2002)“…The identity of amino acid 149 of Escherichia coli ςsgr; 70 has been reported variably as either arginine or aspartic acid. We show that the behavior of both a…”
Get full text
Journal Article