Search Results - "Baldwin, Jeremy G"

Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma by Wagner, Ferdinand, Holzapfel, Boris M., McGovern, Jacqui A., Shafiee, Abbas, Baldwin, Jeremy G., Martine, Laure C., Lahr, Christoph A., Wunner, Felix M., Friis, Thor, Bas, Onur, Boxberg, Melanie, Prodinger, Peter M., Shokoohmand, Ali, Moi, Davide, Mazzieri, Roberta, Loessner, Daniela, Hutmacher, Dietmar W.

“…Existing preclinical murine models often fail to predict effects of anti-cancer drugs. In order to minimize interspecies-differences between murine hosts and…”
Get full text

Cancer cells hijack T-cell mitochondria by Baldwin, Jeremy G., Gattinoni, Luca

“…Nanotube-mediated acquisition of immune cells’ mitochondria by tumour cells is a novel mechanism for immune evasion that can be pharmacologically targeted to…”
Get full text

A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells by McGovern, Jacqui A., Bock, Nathalie, Shafiee, Abbas, Martine, Laure C., Wagner, Ferdinand, Baldwin, Jeremy G., Landgraf, Marietta, Lahr, Christoph A., Meinert, Christoph, Williams, Elizabeth D., Pollock, Pamela M., Denham, Jim, Russell, Pamela J., Risbridger, Gail P., Clements, Judith A., Loessner, Daniela, Holzapfel, Boris M., Hutmacher, Dietmar W.

“…Prostate cancer (PCa) is the second most commonly diagnosed cancer in men, and bone is the most frequent site of metastasis. The tumor microenvironment (TME)…”
Get full text

Biofabricated soft network composites for cartilage tissue engineering by Bas, Onur, De-Juan-Pardo, Elena M, Meinert, Christoph, D'Angella, Davide, Baldwin, Jeremy G, Bray, Laura J, Wellard, R Mark, Kollmannsberger, Stefan, Rank, Ernst, Werner, Carsten, Klein, Travis J, Catelas, Isabelle, Hutmacher, Dietmar W

“…Articular cartilage from a material science point of view is a soft network composite that plays a critical role in load-bearing joints during dynamic loading…”
Get more information

An Integrated Design, Material, and Fabrication Platform for Engineering Biomechanically and Biologically Functional Soft Tissues by Bas, Onur, D’Angella, Davide, Baldwin, Jeremy G, Castro, Nathan J, Wunner, Felix M, Saidy, Navid T, Kollmannsberger, Stefan, Reali, Alessandro, Rank, Ernst, De-Juan-Pardo, Elena M, Hutmacher, Dietmar W

“…We present a design rationale for stretchable soft network composites for engineering tissues that predominantly function under high tensile loads. The…”
Get full text

A Novel 3D Cultured Model for Studying Early Changes in Age‐Related Macular Degeneration by Shokoohmand, Ali, Jeon, June E., Theodoropoulos, Christina, Baldwin, Jeremy G., Hutmacher, Dietmar W., Feigl, Beatrix

“…Various in vitro culture systems have been used to investigate the pathogenesis of age‐related macular degeneration (AMD). However, many still rely on…”
Get full text

Fetal Bone Marrow‐Derived Mesenchymal Stem/Stromal Cells Enhance Humanization and Bone Formation of BMP7 Loaded Scaffolds by Shafiee, Abbas, Baldwin, Jeremy G., Patel, Jatin, Holzapfel, Boris M., Fisk, Nicholas M., Khosrotehrani, Kiarash, Hutmacher, Dietmar W.

“…Tissue engineered constructs built with human cells capable of generating a bone‐like organ within the mouse have attracted considerable interest over the past…”
Get full text

LIM-domain-only 4 (LMO4) enhances CD8+ T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling by Schelker, Roland C., Fioravanti, Jessica, Mastrogiovanni, Fabio, Baldwin, Jeremy G., Rana, Nisha, Li, Peng, Chen, Ping, Vadász, Timea, Spolski, Rosanne, Heuser-Loy, Christoph, Slavkovic-Lukic, Dragana, Noronha, Pedro, Damiano, Giuseppe, Raccosta, Laura, Maggioni, Daniela, Pullugula, Sree, Lin, Jian-Xin, Oh, Jangsuk, Grandinetti, Patrick, Lecce, Mario, Hesse, Leo, Kocks, Emilia, Martín-Santos, Azucena, Gebhard, Claudia, Telford, William G., Ji, Yun, Restifo, Nicholas P., Russo, Vincenzo, Rehli, Michael, Herr, Wolfgang, Leonard, Warren J., Gattinoni, Luca

“…High frequencies of stem-like memory T cells in infusion products correlate with superior patient outcomes across multiple T cell therapy trials. Herein, we…”
Get full text