Search Results - "Baldwin, Amy J."

Polyglycine Acts as a Rejection Signal for Protein Transport at the Chloroplast Envelope by Endow, Joshua K, Rocha, Agostinho Gomes, Baldwin, Amy J, Roston, Rebecca L, Yamaguchi, Toshio, Kamikubo, Hironari, Inoue, Kentaro

“…PolyGly is present in many proteins in various organisms. One example is found in a transmembrane β-barrel protein, translocon at the outer-envelope-membrane…”
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Curcumin and derivatives function through protein phosphatase 2A and presenilin orthologues in Dictyostelium discoideum by Cocorocchio, Marco, Baldwin, Amy J, Stewart, Balint, Kim, Lou, Harwood, Adrian J, Thompson, Christopher R L, Andrews, Paul L R, Williams, Robin S B

“…Natural compounds often have complex molecular structures and unknown molecular targets. These characteristics make them difficult to analyse using a classical…”
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In-frame amber stop codon replacement mutagenesis for the directed evolution of proteins containing non-canonical amino acids: identification of residues open to bio-orthogonal modification by Arpino, James A J, Baldwin, Amy J, McGarrity, Adam R, Tippmann, Eric M, Jones, D Dafydd

“…Expanded genetic code approaches are a powerful means to add new and useful chemistry to proteins at defined residues positions. One such use is the…”
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Functional diversification of thylakoidal processing peptidases in Arabidopsis thaliana by Hsu, Shih-Chi, Endow, Joshua K, Ruppel, Nicholas J, Roston, Rebecca L, Baldwin, Amy J, Inoue, Kentaro

“…Thylakoidal processing peptidase (TPP) is responsible for removing amino-terminal thylakoid-transfer signals from several proteins in the thylakoid lumen…”
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significance of the Dewar valence photoisomer as a UV radiation‐induced DNA photoproduct in marine microbial communities by Meador, Jarah A, Baldwin, Amy J, Pakulski, J. Dean, Jeffrey, Wade H, Mitchell, David L, Douki, Thierry

“…Induction of pyrimidine dimers in DNA by solar UV radiation has drastic effects on microorganisms. To better define the nature of these DNA photoproducts in…”
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Expanded molecular diversity generation during directed evolution by trinucleotide exchange (TriNEx) by Baldwin, Amy J, Busse, Kathy, Simm, Alan M, Jones, D. Dafydd

“…Trinucleotide exchange (TriNEx) is a method for generating novel molecular diversity during directed evolution by random substitution of one contiguous…”
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Complete maturation of the plastid protein translocation channel requires a type I signal peptidase by Inoue, Kentaro, Baldwin, Amy J, Shipman, Rebecca L, Matsui, Kyoko, Theg, Steven M, Ohme-Takagi, Masaru

“…The protein translocation channel at the plastid outer envelope membrane, Toc75, is essential for the viability of plants from the embryonic stage. It is…”
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The most C‐terminal tri‐glycine segment within the polyglycine stretch of the pea Toc75 transit peptide plays a critical role for targeting the protein to the chloroplast outer envelope membrane by Baldwin, Amy J., Inoue, Kentaro

“…The protein translocation channel at the outer envelope membrane of chloroplasts (Toc75) is synthesized as a larger precursor with an N‐terminal transit…”
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Directed evolution of GFP with non-natural amino acids identifies residues for augmenting and photoswitching fluorescence by Reddington, Samuel C, Baldwin, Amy J, Thompson, Rebecca, Brancale, Andrea, Tippmann, Eric M, Jones, D Dafydd

“…Genetic code reprogramming allows proteins to sample new chemistry through the defined and targeted introduction of non-natural amino acids (nAAs). Many useful…”
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Regulation of β-Lactamase Activity by Remote Binding of Heme: Functional Coupling of Unrelated Proteins through Domain Insertion by Edwards, Wayne R, Williams, Abigail J, Morris, Josephine L, Baldwin, Amy J, Allemann, Rudolf K, Jones, D. Dafydd

“…Coupling the activities of normally disparate proteins into one functional unit has significant potential in terms of constructing novel switching components…”
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Investigating protein structural plasticity by surveying the consequence of an amino acid deletion from TEM-1 β-lactamase by Simm, Alan M., Baldwin, Amy J., Busse, Kathy, Jones, D. Dafydd

“…While the deletion of an amino acid is a common mutation observed in nature, it is generally thought to be disruptive to protein structure. Using a directed…”
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Sunlight-induced DNA Damage in Marine Micro-organisms Collected Along a Latitudinal Gradient from 70°N to 68°S by Meador, Jarah A., Baldwin, Amy J., Catala, Phillipe, Jeffrey, Wade H., Joux, Fabien, Moss, Joseph A., Dean Pakulski, J., Stevens, Richard, Mitchell, David L.

“…We examined ultraviolet radiation (UVR)‐induced DNA damage in marine micro‐organisms collected from surface seawater along a latitudinal transect in the…”
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Sunlight-induced DNA damage in marine micro-organisms collected along a latitudinal gradient from 70 degrees N to 68 degrees S by Meador, Jarah A, Baldwin, Amy J, Catala, Phillipe, Jeffrey, Wade H, Joux, Fabien, Moss, Joseph A, Dean Pakulski, J, Stevens, Richard, Mitchell, David L

“…We examined ultraviolet radiation (UVR)-induced DNA damage in marine micro-organisms collected from surface seawater along a latitudinal transect in the…”
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Expanded chemical diversity sampling through whole protein evolution by Baldwin, Amy J, Arpino, James A J, Edwards, Wayne R, Tippmann, Eric M, Jones, D Dafydd

“…A directed evolution method has been developed that allows random substitution of a contiguous trinucleotide sequence for TAG throughout a target gene for use…”
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Transposon-based approaches for generating novel molecular diversity during directed evolution by Jones, D Dafydd, Arpino, James A J, Baldwin, Amy J, Edmundson, Matthew C

“…This chapter introduces a set of transposon-based methods that were developed to sample trinucleotide deletion, trinucleotide replacement, and domain…”
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Directed evolution of GFP with non-natural amino acids identifies residues for augmenting and photoswitching fluorescenceElectronic supplementary information (ESI) available: Detailed experimental methods, supplementary Fig. 1 to 11 and supplementary Tables 1-3. See DOI: 10.1039/c4sc02827a by Reddington, Samuel C, Baldwin, Amy J, Thompson, Rebecca, Brancale, Andrea, Tippmann, Eric M, Jones, D. Dafydd

“…Genetic code reprogramming allows proteins to sample new chemistry through the defined and targeted introduction of non-natural amino acids (nAAs). Many useful…”
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Directed evolution of GFP with non-natural amino acids identifies residues for augmenting and photoswitching fluorescence† †Electronic supplementary information (ESI) available: Detailed experimental methods, supplementary Fig. 1 to 11 and supplementary Tables 1–3. See DOI: 10.1039/c4sc02827a Click here for additional data file by Reddington, Samuel C., Baldwin, Amy J., Thompson, Rebecca, Brancale, Andrea, Tippmann, Eric M., Jones, D. Dafydd

“…Genetic code reprogramming allows proteins to sample new chemistry through targeted introduction of non-natural amino acids. By combining with random codon…”
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The significance of the D ewar valence photoisomer as a UV radiation‐induced DNA photoproduct in marine microbial communities by Meador, Jarah A., Baldwin, Amy J., Pakulski, J. Dean, Jeffrey, Wade H., Mitchell, David L., Douki, Thierry

“…Summary Induction of pyrimidine dimers in DNA by solar UV radiation has drastic effects on microorganisms. To better define the nature of these DNA…”
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Sunlight-induced DNA Damage in Marine Micro-organisms Collected Along a Latitudinal Gradient from 70 degree N to 68 degree S by Meador, Jarah A, Baldwin, Amy J, Catala, Phillipe, Jeffrey, Wade H, Joux, Fabien, Moss, Joseph A, Dean Pakulski, J, Stevens, Richard, Mitchell, David L

“…AbstractWe examined ultraviolet radiation (UVR)-induced DNA damage in marine micro-organisms collected from surface seawater along a latitudinal transect in…”
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Sunlight-induced DNA Damage in Marine Micro-organisms Collected Along a Latitudinal Gradient from 70 degree N to 68 degree S by Meador, Jarah A, Baldwin, Amy J, Catala, Phillipe, Jeffrey, Wade H, Joux, Fabien, Moss, Joseph A, Dean Pakulski, J, Stevens, Richard, Mitchell, David L

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