Search Results - "Baldus, Stephan"

Impact of the 3D microenvironment on phenotype, gene expression, and EGFR inhibition of colorectal cancer cell lines by Luca, Anna C, Mersch, Sabrina, Deenen, René, Schmidt, Stephan, Messner, Isabelle, Schäfer, Karl-Ludwig, Baldus, Stephan E, Huckenbeck, Wolfgang, Piekorz, Roland P, Knoefel, Wolfram T, Krieg, Andreas, Stoecklein, Nikolas H

“…Three-dimensional (3D) tumor cell cultures grown in laminin-rich-extracellular matrix (lrECM) are considered to reflect human tumors more realistic as compared…”
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Depletion of neutrophil extracellular traps in vivo results in hypersusceptibility to polymicrobial sepsis in mice by Meng, Wei, Paunel-Görgülü, Adnana, Flohé, Sascha, Hoffmann, Almuth, Witte, Ingo, MacKenzie, Colin, Baldus, Stephan E, Windolf, Joachim, Lögters, Tim T

“…Although the formation of neutrophil (PMN) extracellular traps (NETs) has been detected during infection and sepsis, their role in vivo is still unclear. This…”
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Myeloperoxidase and its contributory role in inflammatory vascular disease by Lau, Denise, Baldus, Stephan

“…Myeloperoxidase (MPO), a heme protein abundantly expressed in polymorphonuclear neutrophils (PMN), has long been viewed to function primarily as a bactericidal…”
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Inflammatory pathways underlying atrial fibrillation by Friedrichs, Kai, Klinke, Anna, Baldus, Stephan

“…The pathophysiology of atrial fibrillation (AF) remains incompletely understood, despite its prevalence and contributing role in stroke and heart failure…”
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Prevalence and Heterogeneity of KRAS, BRAF, and PIK3CA Mutations in Primary Colorectal Adenocarcinomas and Their Corresponding Metastases by BALDUS, Stephan E, SCHAEFER, Karl-L, ENGERS, Rainer, HARTLEB, Dinah, STOECKLEIN, Nikolas H, GABBERT, Helmut E

“…Purpose: Epidermal growth factor receptor (EGFR) antibody therapy is established in patients with wild-type KRAS colorectal carcinoma; however, up to 50% of…”
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Transcatheter mitral valve repair for functional mitral regurgitation using the Cardioband system: 1 year outcomes by Messika-Zeitoun, David, Nickenig, Georg, Latib, Azeem, Kuck, Karl-Heinz, Baldus, Stephan, Schueler, Robert, La Canna, Giovanni, Agricola, Eustachio, Kreidel, Felix, Huntgeburth, Michael, Zuber, Michel, Verta, Patrick, Grayburn, Paul, Vahanian, Alec, Maisano, Francesco

“…Abstract Aims The Cardioband™ (Edwards Lifesciences) is a transcatheter implant designed to reduce mitral annulus size and mitral regurgitation (MR) severity…”
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Percutaneous Mitral Valve Interventions in the Real World by Maisano, Francesco, MD, Franzen, Olaf, MD, Baldus, Stephan, MD, Schäfer, Ulrich, MD, Hausleiter, Jörg, MD, Butter, Christian, MD, Ussia, Gian Paolo, MD, Sievert, Horst, MD, Richardt, Gert, MD, Widder, Julian D., MD, Moccetti, Tiziano, MD, Schillinger, Wolfgang, MD

“…Objectives The purpose of this article is to report early and mid-term outcomes of the ACCESS-EU study (ACCESS-Europe A Two-Phase Observational Study of the…”
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Serial Changes in Highly Sensitive Troponin I Assay and Early Diagnosis of Myocardial Infarction by Keller, Till, Zeller, Tanja, Ojeda, Francisco, Tzikas, Stergios, Lillpopp, Lars, Sinning, Christoph, Wild, Philipp, Genth-Zotz, Sabine, Warnholtz, Ascan, Giannitsis, Evangelos, Möckel, Martin, Bickel, Christoph, Peetz, Dirk, Lackner, Karl, Baldus, Stephan, Münzel, Thomas, Blankenberg, Stefan

“…CONTEXT Introduction of highly sensitive troponin assays into clinical practice has substantially improved the evaluation of patients with chest pain…”
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Cardioband, a transcatheter surgical-like direct mitral valve annuloplasty system: early results of the feasibility trial by Maisano, Francesco, Taramasso, Maurizio, Nickenig, Georg, Hammerstingl, Christoph, Vahanian, Alec, Messika-Zeitoun, David, Baldus, Stephan, Huntgeburth, Michael, Alfieri, Ottavio, Colombo, Antonio, La Canna, Giovanni, Agricola, Eustachio, Zuber, Michel, Tanner, Felix C, Topilsky, Yan, Kreidel, Felix, Kuck, Karl-Heinz

“…Cardioband system is a direct annuloplasty adjustable device that is implanted in the beating heart on the posterior annulus under fluoroscopic and…”
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MPO (Myeloperoxidase) Reduces Endothelial Glycocalyx Thickness Dependent on Its Cationic Charge by Manchanda, Kashish, Kolarova, Hana, Kerkenpaß, Christina, Mollenhauer, Martin, Vitecek, Jan, Rudolph, Volker, Kubala, Lukas, Baldus, Stephan, Adam, Matti, Klinke, Anna

“…OBJECTIVE—The leukocyte heme-enzyme MPO (myeloperoxidase) exerts proinflammatory effects on the vascular system primarily linked to its catalytic properties…”
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Predictors of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Replacement With the SAPIEN 3 by Mauri, Victor, MD, Reimann, Andreas, Stern, Daniel, MD, Scherner, Maximilian, MD, Kuhn, Elmar, MD, Rudolph, Volker, MD, Rosenkranz, Stephan, MD, Eghbalzadeh, Kaveh, MD, Friedrichs, Kai, MD, Wahlers, Thorsten, MD, Baldus, Stephan, MD, Madershahian, Navid, MD, Rudolph, Tanja K., MD

“…Abstract Objectives The aim of this study was to identify predictors of permanent pacemaker implantation (PPMI) following transcatheter aortic valve…”
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Edoxaban in patients with non-valvular atrial fibrillation after percutaneous coronary intervention: ENCOURAGE-AF design by Baldus, Stephan, Beyer-Westendorf, Jan, Möllmann, Helge, Rottbauer, Wolfgang, Beyerlein, Elisabeth, Goette, Andreas

“…Approximately one fifth of patients diagnosed with atrial fibrillation (AF) undergo a percutaneous coronary intervention (PCI). Current guidelines recommend…”
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Impact of Right Ventricular Dysfunction on Outcomes After Transcatheter Edge-to-Edge Repair for Secondary Mitral Regurgitation by Karam, Nicole, Stolz, Lukas, Orban, Mathias, Deseive, Simon, Praz, Fabien, Kalbacher, Daniel, Westermann, Dirk, Braun, Daniel, Näbauer, Michael, Neuss, Michael, Butter, Christian, Kassar, Mohammad, Petrescu, Aniela, Pfister, Roman, Iliadis, Christos, Unterhuber, Matthias, Park, Sang-Don, Thiele, Holger, Baldus, Stephan, Stephan von Bardeleben, Ralph, Blankenberg, Stefan, Massberg, Steffen, Windecker, Stephan, Lurz, Philipp, Hausleiter, Jörg

“…This study sought to assess the impact of right ventricular dysfunction (RVD) as defined by impaired right ventricular-to-pulmonary artery (RV-PA) coupling, on…”
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Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus by Honke, Nadine, Shaabani, Namir, Cadeddu, Giuseppe, Sorg, Ursula R, Zhang, Dong-Er, Trilling, Mirko, Klingel, Karin, Sauter, Martina, Kandolf, Reinhard, Gailus, Nicole, van Rooijen, Nico, Burkart, Christoph, Baldus, Stephan E, Grusdat, Melanie, Löhning, Max, Hengel, Hartmut, Pfeffer, Klaus, Tanaka, Masato, Häussinger, Dieter, Recher, Mike, Lang, Philipp A, Lang, Karl S

“…Type 1 interferon limits virus replication. Lang and colleagues show that expression of Usp18 in metallophilic macrophages results in less interferon…”
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Sensitive Troponin I Assay in Early Diagnosis of Acute Myocardial Infarction by Keller, Till, Zeller, Tanja, Peetz, Dirk, Tzikas, Stergios, Roth, Alexander, Czyz, Ewa, Bickel, Christoph, Baldus, Stephan, Warnholtz, Ascan, Fröhlich, Meike, Sinning, Christoph R, Eleftheriadis, Medea S, Wild, Philipp S, Schnabel, Renate B, Lubos, Edith, Jachmann, Nicole, Genth-Zotz, Sabine, Post, Felix, Nicaud, Viviane, Tiret, Laurence, Lackner, Karl J, Münzel, Thomas F, Blankenberg, Stefan

“…A highly sensitive assay for troponin I was found to improve on standard serum markers for the diagnosis of acute myocardial infarction. The measurement of…”
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MitraClip therapy in daily clinical practice: initial results from the German transcatheter mitral valve interventions (TRAMI) registry by Baldus, Stephan, Schillinger, Wolfgang, Franzen, Olaf, Bekeredjian, Raffi, Sievert, Horst, Schofer, Joachim, Kuck, Karl-Heinz, Konorza, Thomas, Möllmann, Helge, Hehrlein, Christoph, Ouarrak, Taoufik, Senges, Jochen, Meinertz, Thomas

“…Aims A substantial percentage of patients with mitral regurgitation (MR) in need of mitral valve repair are currently considered not suitable for conventional…”
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Down-regulation of CDH1 is associated with expression of SNAI1 in colorectal adenomas by Kroepil, Feride, Fluegen, Georg, Totikov, Zaurbek, Baldus, Stephan E, Vay, Christian, Schauer, Matthias, Topp, Stefan A, Esch, Jan Schulte Am, Knoefel, Wolfram T, Stoecklein, Nikolas H

“…Down-regulation of E-cadherin (CDH1) and epithelial-mesenchymal transition (EMT) are considered critical events for invasion and metastasis of colorectal…”
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The Enzymatic and Non-Enzymatic Function of Myeloperoxidase (MPO) in Inflammatory Communication by Kargapolova, Yulia, Geißen, Simon, Zheng, Ruiyuan, Baldus, Stephan, Winkels, Holger, Adam, Matti

“…Myeloperoxidase is a signature enzyme of polymorphonuclear neutrophils in mice and humans. Being a component of circulating white blood cells, myeloperoxidase…”
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Impact of Proportionality of Secondary Mitral Regurgitation on Outcome After Transcatheter Mitral Valve Repair by Orban, Mathias, Karam, Nicole, Lubos, Edith, Kalbacher, Daniel, Braun, Daniel, Deseive, Simon, Neuss, Michael, Butter, Christian, Praz, Fabien, Kassar, Mohammad, Petrescu, Aniela, Pfister, Roman, Iliadis, Christos, Unterhuber, Matthias, Lurz, Philipp, Thiele, Holger, Baldus, Stephan, Stephan von Bardeleben, Ralph, Blankenberg, Stefan, Massberg, Steffen, Windecker, Stephan, Hausleiter, Jörg, Orban, Mathias, Stolz, Lukas, Orban, Martin, Braun, Daniel, Näbauer, Michael, Deseive, Simon, Massberg, Steffen, Hausleiter, Jörg, Karam, Nicole, Puscas, Tania, Tence, Noemie, Latremouille, Christian, Lubos, Edith, Kalbacher, Daniel, Westermann, Dirk, Schofer, Niklas, Ludwig, Sebastian, Blankenberg, Stefan, Neuss, Michael, Bannehr, Marvin, Kücken, Tanja, Edlinger, Christoph, Hähnel, Valentin, Butter, Christian, Praz, Fabien, Kassar, Mohammad, Brugger, Nicolas, Pilgrim, Thomas, Winkel, Mirjam G., Windecker, Stephan, Petrescu, Aniela, von Bardeleben, Stephan, Pfister, Roman, Iliadis, Christos, Körber, Maria, Mauri, Viktor, Wösten, Monique, Stephan Baldus, Clemens Metze, Unterhuber, Matthias, Lurz, Philipp, Noack, Thilo, Borger, Michael, Blazek, Stephan, Desch, Steffen, Thiele, Holger

“…The purpose of this paper was to evaluate the impact of proportionality of secondary mitral regurgitation (SMR) in a large real-world registry of transcatheter…”
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Machine Learning Identifies Clinical Parameters to Predict Mortality in Patients Undergoing Transcatheter Mitral Valve Repair by Zweck, Elric, Spieker, Maximilian, Horn, Patrick, Iliadis, Christos, Metze, Clemens, Kavsur, Refik, Tiyerili, Vedat, Nickenig, Georg, Baldus, Stephan, Kelm, Malte, Becher, Marc Ulrich, Pfister, Roman, Westenfeld, Ralf

“…OBJECTIVESThe aim of this study was to develop a machine learning (ML)-based risk stratification tool for 1-year mortality in transcatheter mitral valve repair…”
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