Search Results - "Baldursdóttir, Stefania"

Exploring the Complexity of Processing-Induced Dehydration during Hot Melt Extrusion Using In-Line Raman Spectroscopy by Arnfast, Lærke, van Renterghem, Jeroen, Aho, Johanna, Bøtker, Johan, Raijada, Dhara, Baldursdóttir, Stefania, De Beer, Thomas, Rantanen, Jukka

“…The specific aim in this study was to understand the effect of critical process parameters on the solid form composition of model drug compounds during hot…”
Get full text

Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption by Boegh, Marie, Baldursdóttir, Stefania G., Müllertz, Anette, Nielsen, Hanne M.

“…[Display omitted] Oral delivery of drugs, including peptide and protein therapeutics, can be impeded by the presence of the mucus surface-lining the intestinal…”
Get full text

Qualitative and quantitative analysis of the biophysical interaction of inhaled nanoparticles with pulmonary surfactant by using quartz crystal microbalance with dissipation monitoring by Wan, Feng, Nylander, Tommy, Foged, Camilla, Yang, Mingshi, Baldursdottir, Stefania G., Nielsen, Hanne M.

“…[Display omitted] Understanding the interaction between inhaled nanoparticles and pulmonary surfactant is a prerequisite for predicting the fate of inhaled…”
Get full text

Effect of excipients on encapsulation and release of insulin from spray-dried solid lipid microparticles by Wu, Chengyu, van de Weert, Marco, Baldursdottir, Stefania G., Yang, Mingshi, Mu, Huiling

“…[Display omitted] The study aimed at investigating the potential of spray drying method for encapsulation of protein drugs into solid lipid microparticles (MP)…”
Get full text

In vivo evaluation of solid lipid microparticles and hybrid polymer-lipid microparticles for sustained delivery of leuprolide by Wu, Chengyu, Luo, Xianjin, Baldursdottir, Stefania G., Yang, Mingshi, Sun, Xun, Mu, Huiling

“…[Display omitted] This study aims to investigate the potential of solid lipid microparticles (MP) and hybrid polymer-lipid MPs for sustained delivery of a…”
Get full text

Electrospinnability of Poly Lactic-co-glycolic Acid (PLGA): the Role of Solvent Type and Solvent Composition by Liu, Xiaoli, Baldursdottir, Stefania G., Aho, Johanna, Qu, Haiyan, Christensen, Lars Porskjær, Rantanen, Jukka, Yang, Mingshi

“…ABSTRACT Purpose In this study, the electrospinnability of poly(lactic-co-glycolic acid) (PLGA) solutions was investigated, with a focus on understanding the…”
Get full text

Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities by Pedersen, Pernille Barbre, Vilmann, Peter, Bar-Shalom, Daniel, Müllertz, Anette, Baldursdottir, Stefania

“…To characterize human gastric fluid with regard to rheological properties and gastric lipase activity. In addition, traditional physicochemical properties were…”
Get full text

Adsorption of proteins at the oil/water interface—Observation of protein adsorption by interfacial shear stress measurements by Baldursdottir, Stefania G., Fullerton, Maria Stoier, Nielsen, Signe Hougaard, Jorgensen, Lene

“…The interfacial adsorption of proteins is a problem during processing and formulation. The flexibility and aggregation of the protein cause the formation of a…”
Get full text

Lipid Shell-Enveloped Polymeric Nanoparticles with High Integrity of Lipid Shells Improve Mucus Penetration and Interaction with Cystic Fibrosis-Related Bacterial Biofilms by Wan, Feng, Nylander, Tommy, Klodzinska, Sylvia Natalie, Foged, Camilla, Yang, Mingshi, Baldursdottir, Stefania G, M. Nielsen, Hanne

“…Nanoparticle (NP) mediated drug delivery into viscous biomatrices, e.g., mucus and bacterial biofilms, is challenging. Lipid shell-enveloped polymeric NPs…”
Get full text

Particle formation and characteristics of Celecoxib-loaded poly(lactic-co-glycolic acid) microparticles prepared in different solvents using electrospraying by Bohr, Adam, Yang, Mingshi, Baldursdóttir, Stefanía, Kristensen, Jakob, Dyas, Mark, Stride, Eleanor, Edirisinghe, Mohan

“…Microparticles were fabricated for pharmaceutical purposes using electrospraying with the aim to determine the effect of the solvent(s) used. Particles of…”
Get full text

Melt Extrusion of High-Dose Co-Amorphous Drug-Drug Combinations by Arnfast, Lærke, Kamruzzaman, Md, Löbmann, Korbinian, Aho, Johanna, Baldursdottir, Stefania, Rades, Thomas, Rantanen, Jukka

“…Purpose Many future drug products will be based on innovative manufacturing solutions, which will increase the need for a thorough understanding of the…”
Get full text

Pharmaceutical microparticle engineering with electrospraying: the role of mixed solvent systems in particle formation and characteristics by Bohr, Adam, Wan, Feng, Kristensen, Jakob, Dyas, Mark, Stride, Eleanor, Baldursdottír, Stefania, Edirisinghe, Mohan, Yang, Mingshi

“…Microparticles of Celecoxib, dispersed in a matrix of poly(lactic-co-glycolic acid) (PLGA), were prepared by electrospraying using different solvent mixtures…”
Get full text

Molecular weight-dependent degradation and drug release of surface-eroding poly(ethylene carbonate) by Bohr, Adam, Wang, Yingya, Harmankaya, Necati, Water, Jorrit J., Baldursdottír, Stefania, Almdal, Kristoffer, Beck-Broichsitter, Moritz

“…[Display omitted] Poly(ethylene carbonate) (PEC) is a unique biomaterial showing significant potential for controlled drug delivery applications. The current…”
Get full text

Modulating Protein Release Profiles by Incorporating Hyaluronic Acid into PLGA Microparticles Via a Spray Dryer Equipped with a 3-Fluid Nozzle by Wan, Feng, Maltesen, Morten Jonas, Andersen, Sune Klint, Bjerregaard, Simon, Baldursdottir, Stefania G., Foged, Camilla, Rantanen, Jukka, Yang, Mingshi

“…ABSTRACT Purpose The purpose of this study was to modulate the release profiles of the model protein drug from spray dried poly(DL-lactic-co-glycolic acid)…”
Get full text

Impact of PLGA molecular behavior in the feed solution on the drug release kinetics of spray dried microparticles by Wan, Feng, Wu, Jian X., Bohr, Adam, Baldursdottir, Stefania G., Maltesen, Morten Jonas, Bjerregaard, Simon, Foged, Camilla, Rantanen, Jukka, Yang, Mingshi

“…The purpose of this study was to understand the impact of the poly (lactic-co-glycolic acid) (PLGA) molecular behavior in the feed solution on the drug release…”
Get full text

The influence of size, structure and hydrophilicity of model surfactants on the adsorption of lysozyme to oil–water interface—Interfacial shear measurements by Baldursdottir, Stefania G., Jorgensen, Lene

“…[Display omitted] ► The influence of surfactants on lysozyme adsorption to oil–water interfaces. ► The lysozyme adsorption was prevented by addition of…”
Get full text

Characterization of Riboflavin-Photosensitized Changes in Aqueous Solutions of Alginate by Dynamic Light Scattering by Kjoniksen, Anna-Lena, Baldursdottir, Stefania G, Nystrom, Bo

“…The effect of irradiation, in the wavelength range of 310–800 nm, on aqueous solutions (pH = 7.4) of alginate in the presence of the photosensitizer riboflavin…”
Get full text

Behaviour of stereoblock poly(N-isopropyl acrylamide) in acetone–water mixtures by Munk, Tommy, Hietala, Sami, Kalliomäki, Katriina, Nuopponen, Markus, Tenhu, Heikki, Tian, Fang, Rantanen, Jukka, Baldursdóttir, Stefanía

“…The purpose of this study was to investigate the usability of poly( N -isopropyl acrylamide) (PNIPAM) as an additive for crystallization of a model drug,…”
Get full text

The influence of thermal history on the physical behavior of poly(ethylene glycol) (PEG) by Baldursdottir, Stefania, Tian, Fang, Santacruz, Bruno Gallo, Jørgensen, Anna Cecilia, Rantanen, Jukka

“…Objectives: To investigate the influence of thermal history on the physical behavior of poly(ethylene glycol) (PEG), commonly used as a pharmaceutical…”
Get full text

The effect of riboflavin-photoinduced degradation of alginate matrices on the diffusion of poly(oxyethylene) probes in the polymer network by Baldursdottir, Stefania G, Kjoniksen, Anna-Lena, Nystrom, Bo

“…The effect of irradiation, in the wavelength range of 310–800 nm, on the tracer diffusion of poly(oxyethylene) (POE) of different molecular weights embedded in…”
Get full text