Search Results - "Baldini, Francesca"
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The Anti-Inflammatory Potential of an Ethanolic Extract from Sarcopoterium spinosum Fruits for Protection and/or Counteraction against Oxidative Stress in Dysfunctional Endothelial Cells
Published in International journal of molecular sciences (01-02-2024)“…Plants and plant extracts are a relevant source of bioactive compounds widely employed as functional foods. In the Mediterranean area, the shrub is…”
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Unraveling the metabolic activities of bioactive compounds on cellular models of hepatosteatosis and adipogenesis through docking analysis with PPARs
Published in Scientific reports (15-11-2024)“…Obesity is associated with fatty liver disease. Available therapies show modest efficacy, and nutraceuticals with good effectiveness and safety are largely…”
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The Potential of Lamiaceae Herbs for Mitigation of Overweight, Obesity, and Fatty Liver: Studies and Perspectives
Published in Molecules (Basel, Switzerland) (08-08-2022)“…Numerous plants, plant extracts, and plant-derived compounds are being explored for their beneficial effects against overweight and liver diseases. Obesity is…”
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An Overview of Long Non-Coding (lnc)RNAs in Neuroblastoma
Published in International journal of molecular sciences (19-04-2021)“…Neuroblastoma (NB) is a heterogeneous developmental tumor occurring in childhood, which arises from the embryonic sympathoadrenal cells of the neural crest…”
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New Perspectives of S-Adenosylmethionine (SAMe) Applications to Attenuate Fatty Acid-Induced Steatosis and Oxidative Stress in Hepatic and Endothelial Cells
Published in Molecules (Basel, Switzerland) (15-09-2020)“…S-adenosylmethionine (SAMe) is an endogenous methyl donor derived from ATP and methionine that has pleiotropic functions. Most SAMe is synthetized and consumed…”
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Silybin counteracts lipid excess and oxidative stress in cultured steatotic hepatic cells
Published in World journal of gastroenterology : WJG (14-07-2016)“…AIM: To investigate in vitro the therapeutic effect and mechanisms of silybin in a cellular model of hepatic steatosis.METHODS: Rat hepatoma Fa O cells were…”
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Efficacy of a Three Drug-Based Therapy for Neuroblastoma in Mice
Published in International journal of molecular sciences (01-07-2021)“…High-risk neuroblastoma (HR-NB) still remains the most dangerous tumor in early childhood. For this reason, the identification of new therapeutic approaches is…”
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Relationship between Liver Stiffness and Steatosis in Obesity Conditions: In Vivo and In Vitro Studies
Published in Biomolecules (Basel, Switzerland) (23-05-2022)“…Obesity is a major risk factor for metabolic dysfunction such as non-alcoholic fatty liver disease (NAFLD). The NAFLD spectrum ranges from simple steatosis, to…”
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Reactive Astrocytosis in a Mouse Model of Chronic Polyamine Catabolism Activation
Published in Biomolecules (Basel, Switzerland) (25-08-2021)“…In the brain, polyamines are mainly synthesized in neurons, but preferentially accumulated in astrocytes, and are proposed to be involved in…”
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MCM2 and Carbonic Anhydrase 9 Are Novel Potential Targets for Neuroblastoma Pharmacological Treatment
Published in Biomedicines (03-11-2020)“…To overcome the lack of effective pharmacological treatments for high-risk neuroblastoma (HR-NB), the development of novel in vitro and in vivo models that…”
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The Nutraceutic Silybin Counteracts Excess Lipid Accumulation and Ongoing Oxidative Stress in an In Vitro Model of Non-Alcoholic Fatty Liver Disease Progression
Published in Frontiers in nutrition (Lausanne) (19-09-2017)“…Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver-related morbidity and mortality. Oxidative stress and release of pro-inflammatory…”
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The Anti-Inflammatory Potential of an Ethanolic Extract from ISarcopoterium spinosum/I Fruits for Protection and/or Counteraction against Oxidative Stress in Dysfunctional Endothelial Cells
Published in International journal of molecular sciences (01-01-2024)“…Plants and plant extracts are a relevant source of bioactive compounds widely employed as functional foods. In the Mediterranean area, the shrub Sarcopoterium…”
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Photobiomodulation with 808-nm diode laser light promotes wound healing of human endothelial cells through increased reactive oxygen species production stimulating mitochondrial oxidative phosphorylation
Published in Lasers in medical science (01-04-2019)“…Photobiomodulation of cells using near-infrared (NIR) monochromatic light can affect cell functions such as proliferation, viability, and metabolism in a range…”
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Unveiling nuclear chromatin distribution using IsoConcentraChromJ: A flourescence imaging plugin for IsoRegional and IsoVolumetric based ratios analysis
Published in PloS one (02-07-2024)“…Chromatin exhibits non-random distribution within the nucleus being arranged into discrete domains that are spatially organized throughout the nuclear space…”
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Antisteatotic and antioxidant activities of Thymbra spicata L. extracts in hepatic and endothelial cells as in vitro models of non-alcoholic fatty liver disease
Published in Journal of ethnopharmacology (15-07-2019)“…Thymbra spicata, a member of the Lamiaceae family, is native to eastern Mediterranean area. Leaves of this plant are rich in phenolic compounds and are a…”
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Adipocyte hypertrophy parallels alterations of mitochondrial status in a cell model for adipose tissue dysfunction in obesity
Published in Life sciences (1973) (15-01-2021)“…Adipocyte hypertrophy is the main cause of obesity. A deeper understanding of the molecular mechanisms regulating adipocyte dysfunction may help to plan…”
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Adipocyte-hepatocyte crosstalk in cellular models of obesity: Role of soluble factors
Published in Life sciences (1973) (15-03-2023)“…Hepatic steatosis is often a consequence of obesity. Adipose tissue is an important endocrine regulator of metabolic homeostasis in the body. In obesity,…”
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New insights in Progerin-induced modifications of chromatin landscapes
Published in Biophysical journal (10-02-2023)Get full text
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Optical nanoscopy approach to unveil chromatin alterations implicated in neuroblastoma transformation
Published in Biophysical journal (10-02-2023)Get full text
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