Search Results - "Baldeschwieler, J D"

Evidence for the Role of Proteoglycans in Cation-Mediated Gene Transfer by Mislick, Kimberly A., Baldeschwieler, John D.

“…We report evidence that gene complexes, consisting of polycations and plasmid DNA enter cells via binding to membrane-associated proteoglycans. Treatment of…”
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Subfibrillar structure of type I collagen observed by atomic force microscopy by Baselt, D.R., Revel, J.P., Baldeschwieler, J.D.

“…We have imaged native rat tail and reconstituted bovine dermal type I collagen by atomic force microscopy, obtaining a level of detail comparable to that…”
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Real-time detection of DNA hybridization and melting on oligonucleotide arrays by using optical wave guides by Stimpson, D.I, Houer, J.V, Hsieh, W.T, Jou, C, Gordon, J, Theriault, T, Gamble, R, Baldeschwieler, J.D

“…The challenge of the Human Genome Project is to increase the rate of DNA sequence acquisition by two orders of magnitude to complete sequencing of the human…”
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Atomic-scale imaging of DNA using scanning tunnelling microscopy by Driscoll, Robert J, Youngquist, Michael G, Baldeschwieler, John D

“…The scanning tunnelling microscope (STM) has been used to visualize DNA under water, under oil and in air. Images of single-stranded DNA have shown that…”
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Atomic Force Microscopy of Human Hair Cuticles: A Microscopic Study of Environmental Effects on Hair Morphology by O'Connor, Stephen D., Komisarek, Kimberly L., Baldeschwieler, John D.

“…We have used an atomic force microscope to provide quantitative real-time analysis of human hair morphologic changes under ambient conditions. This form of…”
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Phagocytosis of Liposomes By Human Platelets by Male, Roxanne, Vannier, Wilton E., Baldeschwieler, John D.

“…We have shown that platelets are capable of phagocytosing liposomes rather than simply sequestering particles as previously postulated. Incubation of human…”
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Spatially resolved chemical analysis with an NSOM-based laser desorption microprobe by Kossakovski, D.A, O'Connor, S.D, Widmer, M, Baldeschwieler, J.D, Beauchamp, J.L

“…A new instrument for simultaneous analysis of surface topography and chemical composition has been developed. An uncoated probe of a near-field scanning…”
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Organ distributions of liposome-loaded rat platelets by Male, R, Moon, D G, Garvey, J S, Vannier, W E, Baldeschwieler, J D

“…Past in vitro functional assays have demonstrated that platelet function is not inhibited by liposome uptake. In the present study, the organ distributions of…”
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In vivo Stability of Ester- and Ether-Linked Phospholipid-Containing Liposomes as Measured by Perturbed Angular Correlation Spectroscopy by Derksen, Johannes T., Baldeschwieler, John D., Scherphof, Gerrit L.

“…To evaluate liposome formulations for use as intracellular sustained-release drug depots, we have compared the uptake and degradation in rat liver and spleen…”
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Suppression of Liver Uptake of Liposomes by Dextran Sulfate 500 by Patel, Kanaiyalal R., Li, Ming P., Baldeschwieler, John D.

“…The effect of dextran sulfate (DS, 500,000 Mr) and multilamellar vesicles (MLV) as liver blockade agents has been investigated in mice. Intravenous injection…”
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'Oxide-free' tip for scanning tunneling microscopy by Colton, R. J., Baker, S. M., Baldeschwieler, J. D., Kaiser, W. J.

“…A new tip for scanning tunneling microscopy and a tip repair procedure that allows one to reproducibly obtain atomic images of highly oriented pyrolytic…”
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Imaging graphite in air by scanning tunneling microscopy - Role of the tip by Colton, R. J., Baker, S. M., Driscoll, R. J., Youngquist, M. G., Baldeschwieler, J. D., Kaiser, W. J.

“…Atomically resolved images of highly oriented pyrolytic graphite (HOPG) in air at point contact have been obtained. Direct contact between tip and sample or…”
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Targeting of Lipid Vesicles: Specificity of Carbohydrate Receptor Analogues for Leukocytes in Mice by Mauk, Marcia R., Gamble, Ronald C., Baldeschwieler, John D.

“…The presence of particular surface carbohydrate modifications is shown to affect dramatically the stability and tissue specificity of unilamellar distearoyl…”
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Fluorescence measurement of the kinetics of DNA injection by bacteriophage .lambda. into liposomes by Novick, Steven L, Baldeschwieler, John D

“…Bacteriophage lambda attaches to Gram-negative bacteria using the outer membrane protein LamB as its receptor. Subsequently, DNA is injected by the…”
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Transfection of Folate-Polylysine DNA Complexes: Evidence for Lysosomal Delivery by Mislick, Kimberly A, Baldeschwieler, John D, Kayyem, Jon F, Meade, Thomas J

“…We are utilizing the folate receptor for the intracellular delivery of DNA. In this study, a folate-poly-L-lysine (FPLL) conjugate was synthesized and…”
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Characterization of pH-Dependent Poly(acrylic Acid) Complexation with Phospholipid Vesicles by Fujiwara, Mitsuko, Grubbs, Robert H., Baldeschwieler, John D.

“…The pH-dependent complexation of poly(acrylic acid) (PAA) with phospholipid (phosphatidylcholine) vesicles was characterized by fluorescence polarization,…”
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The pharmacological efficacy of a rigid non-phospholipid liposome drug delivery system by Patel, K R, Li, M P, Schuh, J R, Baldeschwieler, J D

“…Hydration of an ethoxylate derivative of cholesterol, triethoxycholesterol, results in the formation of stable, rigid, bilayer-like structures capable of…”
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Phagocytosis Of Carbohydrate-Modified Phospholipid Vesicles by Macrophage by Wu, Po-shun, Tin, George W., Baldeschwieler, John D.

“…Modification of the surface of distearoyl phosphatidylcholine vesicles with synthetic glycolipids dramatically affects the rate of uptake of these vesicles by…”
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Tumor-Imaging Potential of Liposomes Loaded with In-111-NTA: Biodistribution in Mice by Proffitt, Richard T, Williams, Lawrence E, Presant, Cary A, Tin, George W, Uliana, Joseph A, Gamble, Ronald C, Baldeschwieler, John D

“…EMT6 tumors in BALB/c mice have been successfully imaged with small (less than 0.1 mu), unilamellar lipid vesicles (SUVs) loaded with In-111 nitrilotriacetic…”
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Modification of lipid phase behavior with membrane-bound cryoprotectants by Goodrich, R P, Handel, T M, Baldeschwieler, J D

“…Several derivatives of cholesterol containing oxyethylene headgroups with and without a terminal galactose have been synthesized in order to examine the…”
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