Search Results - "Baldeosingh, Rajkumar"

Hepatic Stellate Cells and Hepatocarcinogenesis by Barry, Anna E., Baldeosingh, Rajkumar, Lamm, Ryan, Patel, Keyur, Zhang, Kai, Dominguez, Dana A., Kirton, Kayla J., Shah, Ashesh P., Dang, Hien

“…Hepatic stellate cells (HSCs) are a significant component of the hepatocellular carcinoma (HCC) tumor microenvironment (TME). Activated HSCs transform into…”
Get full text

An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy by Bhutto, Imran A, Ogura, Shuntaro, Baldeosingh, Rajkumar, McLeod, D Scott, Lutty, Gerard A, Edwards, Malia M

“…Geographic atrophy (GA) is the late stage of non-neovascular age-related macular degeneration. A lack of animal models for GA has hampered treatment efforts…”
Get full text

The Friend of GATA Transcriptional Co-Regulator, U-Shaped, Is a Downstream Antagonist of Dorsal-Driven Prohemocyte Differentiation in Drosophila by Gao, Hongjuan, Baldeosingh, Rajkumar, Wu, Xiaorong, Fossett, Nancy

“…Recent studies suggest that mammalian hematopoietic stem and progenitor cells (HSPCs) respond directly to infection and inflammatory signaling. These signaling…”
Get full text

Hedgehog signaling from the Posterior Signaling Center maintains U-shaped expression and a prohemocyte population in Drosophila by Baldeosingh, Rajkumar, Gao, Hongjuan, Wu, Xiaorong, Fossett, Nancy

“…Hematopoietic progenitor choice between multipotency and differentiation is tightly regulated by intrinsic factors and extrinsic signals from the surrounding…”
Get full text

A role for mast cells in geographic atrophy by Ogura, Shuntaro, Baldeosingh, Rajkumar, Bhutto, Imran A., Kambhampati, Siva P., Scott McLeod, Donald, Edwards, Malia M., Rais, Rana, Schubert, William, Lutty, Gerard A.

“…Mast cells (MCs) are the initial responders of innate immunity and their degranulation contribute to various etiologies. While the abundance of MCs in the…”
Get full text

Mast Cell-Derived Tryptase in Geographic Atrophy by McLeod, D Scott, Bhutto, Imran, Edwards, Malia M, Gedam, Manasee, Baldeosingh, Rajkumar, Lutty, Gerard A

“…Our previous study demonstrated significantly more degranulating mast cells (MCs) in choroids from subjects with age-related macular degeneration compared to…”
Get full text

The PAX-SIX-EYA-DACH network modulates GATA-FOG function in fly hematopoiesis and human erythropoiesis by Creed, T Michael, Baldeosingh, Rajkumar, Eberly, Christian L, Schlee, Caroline S, Kim, MinJung, Cutler, Jevon A, Pandey, Akhilesh, Civin, Curt I, Fossett, Nancy G, Kingsbury, Tami J

“…The GATA and PAX-SIX-EYA-DACH transcriptional networks (PSEDNs) are essential for proper development across taxa. Here, we demonstrate novel PSEDN roles in…”
Get full text

Hedgehog Signaling Regulates Friend of GATA to Maintain Hematopoietic Progenitor Cells in Drosophila melanogaster by Baldeosingh, Rajkumar

“…Hematopoietic stem cells must be capable of both self-renewal and production of progenitor cells that give rise to all of the blood cell types, the two basic…”
Get full text

Hedgehog Signaling Regulates Friend of GATA to Maintain Hematopoietic Progenitor Cells in Drosophila melanogaster by Baldeosingh, Rajkumar

“…Hematopoietic stem cells must be capable of both self-renewal and production of progenitor cells that give rise to all of the blood cell types, the two basic…”
Get full text