Search Results - "Baldauf, Michaela C"

Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes by Musa, Julian, Cidre-Aranaz, Florencia, Aynaud, Marie-Ming, Orth, Martin F., Knott, Maximilian M. L., Mirabeau, Olivier, Mazor, Gal, Varon, Mor, Hölting, Tilman L. B., Grossetête, Sandrine, Gartlgruber, Moritz, Surdez, Didier, Gerke, Julia S., Ohmura, Shunya, Marchetto, Aruna, Dallmayer, Marlene, Baldauf, Michaela C., Stein, Stefanie, Sannino, Giuseppina, Li, Jing, Romero-Pérez, Laura, Westermann, Frank, Hartmann, Wolfgang, Dirksen, Uta, Gymrek, Melissa, Anderson, Nathaniel D., Shlien, Adam, Rotblat, Barak, Kirchner, Thomas, Delattre, Olivier, Grünewald, Thomas G. P.

“…Pediatric malignancies including Ewing sarcoma (EwS) feature a paucity of somatic alterations except for pathognomonic driver-mutations that cannot explain…”
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Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma by Marchetto, Aruna, Ohmura, Shunya, Orth, Martin F., Knott, Maximilian M. L., Colombo, Maria V., Arrigoni, Chiara, Bardinet, Victor, Saucier, David, Wehweck, Fabienne S., Li, Jing, Stein, Stefanie, Gerke, Julia S., Baldauf, Michaela C., Musa, Julian, Dallmayer, Marlene, Romero-Pérez, Laura, Hölting, Tilman L. B., Amatruda, James F., Cossarizza, Andrea, Henssen, Anton G., Kirchner, Thomas, Moretti, Matteo, Cidre-Aranaz, Florencia, Sannino, Giuseppina, Grünewald, Thomas G. P.

“…Ewing sarcoma (EwS) is an aggressive childhood cancer likely originating from mesenchymal stem cells or osteo-chondrogenic progenitors. It is characterized by…”
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Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets by Baldauf, Michaela C, Orth, Martin F, Dallmayer, Marlene, Marchetto, Aruna, Gerke, Julia S, Rubio, Rebeca Alba, Kiran, Merve M, Musa, Julian, Knott, Maximilian M L, Ohmura, Shunya, Li, Jing, Akpolat, Nusret, Akatli, Ayse N, Özen, Özlem, Dirksen, Uta, Hartmann, Wolfgang, de Alava, Enrique, Baumhoer, Daniel, Sannino, Giuseppina, Kirchner, Thomas, Grünewald, Thomas G P

“…Ewing sarcoma is an undifferentiated small-round-cell sarcoma. Although molecular detection of pathognomonic fusions such as enables definitive diagnosis,…”
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Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma by Orth, Martin F., Gerke, Julia S., Knösel, Thomas, Altendorf‐Hofmann, Annelore, Musa, Julian, Alba‐Rubio, Rebeca, Stein, Stefanie, Hölting, Tilman L. B., Cidre‐Aranaz, Florencia, Romero‐Pérez, Laura, Dallmayer, Marlene, Baldauf, Michaela C., Marchetto, Aruna, Sannino, Giuseppina, Knott, Maximilian M. L., Wehweck, Fabienne, Ohmura, Shunya, Li, Jing, Hakozaki, Michiyuki, Kirchner, Thomas, Dandekar, Thomas, Butt, Elke, Grünewald, Thomas G. P.

“…Soft‐tissue sarcomas are rare, heterogeneous, and often aggressive mesenchymal cancers. Many of them are associated with poor outcome, partially because…”
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Publisher Correction: Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma by Marchetto, Aruna, Ohmura, Shunya, Orth, Martin F., Knott, Maximilian M. L., Colombo, Maria V., Arrigoni, Chiara, Bardinet, Victor, Saucier, David, Wehweck, Fabienne S., Li, Jing, Stein, Stefanie, Gerke, Julia S., Baldauf, Michaela C., Musa, Julian, Dallmayer, Marlene, Romero-Pérez, Laura, Hölting, Tilman L. B., Amatruda, James F., Cossarizza, Andrea, Henssen, Anton G., Kirchner, Thomas, Moretti, Matteo, Cidre-Aranaz, Florencia, Sannino, Giuseppina, Grünewald, Thomas G. P.

“…A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20017-2…”
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Systematic identification of cancer-specific MHC-binding peptides with RAVEN by Baldauf, Michaela C., Gerke, Julia S., Kirschner, Andreas, Blaeschke, Franziska, Effenberger, Manuel, Schober, Kilian, Rubio, Rebeca Alba, Kanaseki, Takayuki, Kiran, Merve M., Dallmayer, Marlene, Musa, Julian, Akpolat, Nurset, Akatli, Ayse N., Rosman, Fernando C., Özen, Özlem, Sugita, Shintaro, Hasegawa, Tadashi, Sugimura, Haruhiko, Baumhoer, Daniel, Knott, Maximilian M. L., Sannino, Giuseppina, Marchetto, Aruna, Li, Jing, Busch, Dirk H., Feuchtinger, Tobias, Ohmura, Shunya, Orth, Martin F., Thiel, Uwe, Kirchner, Thomas, Grünewald, Thomas G. P.

“…Immunotherapy can revolutionize anti-cancer therapy if specific targets are available. Immunogenic peptides encoded by cancer-specific genes (CSGs) may enable…”
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Are EWSR1-NFATc2-positive sarcomas really Ewing sarcomas? by Baldauf, Michaela C., Gerke, Julia S., Orth, Martin F., Dallmayer, Marlene, Baumhoer, Daniel, de Alava, Enrique, Hartmann, Wolfgang, Kirchner, Thomas, Grünewald, Thomas G.P.

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MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress by Sipol, Alexandra, Hameister, Erik, Xue, Busheng, Hofstetter, Julia, Barenboim, Maxim, Öllinger, Rupert, Jain, Gaurav, Prexler, Carolin, Rubio, Rebeca Alba, Baldauf, Michaela C., Franchina, Davide G., Petry, Andreas, Schmäh, Juliane, Thiel, Uwe, Görlach, Agnes, Cario, Gunnar, Brenner, Dirk, Richter, Günther H.S., Grünewald, Thomas G.P., Rad, Roland, Wolf, Elmar, Ruland, Jürgen, Sorensen, Poul H., Burdach, Stefan E.G.

“…Cancer cells are in most instances characterized by rapid proliferation and uncontrolled cell division. Hence, they must adapt to proliferation-induced…”
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Are EWSR1-NFATc2-positive sarcomas really Ewing sarcomas? by Baldauf, Michaela C., Gerke, Julia S., Orth, Martin F., Dallmayer, Marlene, Baumhoer, Daniel, de Alava, Enrique, Hartmann, Wolfgang, Kirchner, Thomas, Grünewald, Thomas G. P.

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Pembrolizumab-Associated CD8+ Vasculitic Mononeuritis Multiplex in a Patient With Mesothelioma by Baldauf, Michaela C., Kapauer, Monika, Joerger, Markus, Flatz, Lukas, Rodriguez, Regulo, Frank, Stephan, Felbecker, Ansgar, Hartmann-Fussenegger, Susanne, Hundsberger, Thomas

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High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma by Orth, Martin F, Hölting, Tilman L B, Dallmayer, Marlene, Wehweck, Fabienne S, Paul, Tanja, Musa, Julian, Baldauf, Michaela C, Surdez, Didier, Delattre, Olivier, Knott, Maximilian M L, Romero-Pérez, Laura, Kasan, Merve, Cidre-Aranaz, Florencia, Gerke, Julia S, Ohmura, Shunya, Li, Jing, Marchetto, Aruna, Henssen, Anton G, Özen, Özlem, Sugita, Shintaro, Hasegawa, Tadashi, Kanaseki, Takayuki, Bertram, Stefanie, Dirksen, Uta, Hartmann, Wolfgang, Kirchner, Thomas, Grünewald, Thomas G P

“…Ewing sarcoma (EwS) is an aggressive cancer displaying an undifferentiated small-round-cell histomorphology that can be easily confused with a broad spectrum…”
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Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma by Dallmayer, Marlene, Li, Jing, Ohmura, Shunya, Alba Rubio, Rebeca, Baldauf, Michaela C., Hölting, Tilman L. B., Musa, Julian, Knott, Max M. L., Stein, Stefanie, Cidre-Aranaz, Florencia, Wehweck, Fabienne S., Romero-Pérez, Laura, Gerke, Julia S., Orth, Martin F., Marchetto, Aruna, Kirchner, Thomas, Bach, Horacio, Sannino, Giuseppina, Grünewald, Thomas G. P.

“…Ewing sarcoma (EwS) is an aggressive cancer characterized by chromosomal translocations generating fusions of the EWSR1 gene with ETS transcription factors (in…”
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Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8+ T cells directed against tumor-associated antigens by Kirschner, Andreas, Thiede, Melanie, Blaeschke, Franziska, Richter, Günther H S, Gerke, Julia S, Baldauf, Michaela C, Grünewald, Thomas G P, Busch, Dirk H, Burdach, Stefan, Thiel, Uwe

“…Autologous as well as allogeneic CD8+ T cells transduced with tumor antigen specific T cell receptors (TCR) may cause significant tumor lysis upon adoptive…”
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