Search Results - "Baldascini, H"

Rapid whole monoclonal antibody analysis by mass spectrometry: An Ultra scale-down study of the effect of harvesting by centrifugation on the post-translational modification profile by Reid, C.Q, Tait, A, Baldascini, H, Mohindra, A, Racher, A, Bilsborough, S, Smales, C.M, Hoare, M

“…With the trend towards the generation and production of increasing numbers of complex biopharmaceutical (protein based) products, there is an increased need…”
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Ultra scale-down approach to correct dispersive and retentive effects in small-scale columns when predicting larger scale elution profiles by Hutchinson, N., Chhatre, S., Baldascini, H., Davies, J. L., Bracewell, D. G., Hoare, M.

“…Ultra scale‐down approaches represent valuable methods for chromatography development work in the biopharmaceutical sector, but for them to be of value,…”
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Impact of clarification strategy on chromatographic separations: Pre-processing of cell homogenates by Bracewell, D.G, Boychyn, M, Baldascini, H, Storey, S.A, Bulmer, M, More, J, Hoare, M

“…This research focused on how the extent and type of primary solid-liquid separation can affect the performance of guard filtration and chromatography, in this…”
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Interfacial inactivation of epoxide hydrolase in a two-liquid-phase system by Baldascini, Helen, Janssen, Dick B.

“…Enantioselective epoxide hydrolases are useful biocatalysts for the preparation of enantiopure epoxides and diols. The kinetic resolution of racemic epoxides…”
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Inactivation of epoxide hydrolase by catalysis-induced formation of isoaspartate by van Loo, Bert, Permentier, Hjalmar P., Kingma, Jaap, Baldascini, Helen, Janssen, Dick B.

“…Epoxide hydrolases catalyze hydrolytic epoxide ring-opening, most often via formation of a covalent hydroxyalkyl-enzyme intermediate. A mutant of Agrobacterium…”
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Effect of mass transfer limitations on the enzymatic kinetic resolution of epoxides in a two-liquid-phase system by Baldascini, Helen, Ganzeveld, Klaassien J., Janssen, Dick B., Beenackers, Antonie A. C. M.

“…Optically active epoxides can be obtained by kinetic resolution of racemic mixtures using enantioselective epoxide hydrolases. To increase the productivity of…”
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