Search Results - "Balda, Maria S."
-
1
Tight junctions: from simple barriers to multifunctional molecular gates
Published in Nature reviews. Molecular cell biology (01-09-2016)“…Key Points Tight junctions are intercellular adhesion complexes in epithelia and endothelia that control paracellular permeability. This paracellular diffusion…”
Get full text
Journal Article -
2
ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation
Published in The Journal of cell biology (16-03-2015)“…Intercellular junctions are crucial for mechanotransduction, but whether tight junctions contribute to the regulation of cell-cell tension and adherens…”
Get full text
Journal Article -
3
Tight junctions and the regulation of gene expression
Published in Biochimica et biophysica acta (01-04-2009)“…Cell adhesion is a key regulator of cell differentiation. Cell interactions with neighboring cells and the extracellular matrix regulate gene expression, cell…”
Get full text
Journal Article -
4
Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly
Published in Cell reports (Cambridge) (21-07-2020)“…Tight-junction-regulated actomyosin activity determines epithelial and endothelial tension on adherens junctions and drives morphogenetic processes; however,…”
Get full text
Journal Article -
5
Rho Signaling and Tight Junction Functions
Published in Physiology (Bethesda, Md.) (01-02-2010)“…Steve Terry , Mei Nie , Karl Matter and Maria S. Balda Department of Cell Biology, UCL Institute of Ophthalmology, University College London, London, United…”
Get full text
Journal Article -
6
Stress- and Rho-activated ZO-1–associated nucleic acid binding protein binding to p21 mRNA mediates stabilization, translation, and cell survival
Published in Proceedings of the National Academy of Sciences - PNAS (03-07-2012)“…A central component of the cellular stress response is p21 ᵂᴬF¹/Cᴵᴾ¹, which regulates cell proliferation, survival, and differentiation. Inflammation and cell…”
Get full text
Journal Article -
7
Proper E‐cadherin membrane location in colon requires Dab2 and it modifies by inflammation and cancer
Published in Journal of cellular physiology (01-02-2021)“…We reported that Disabled‐2 (Dab2) is located at the apical membrane in suckling rat intestine. Here, we discovered that, in colon of suckling and adult mouse…”
Get full text
Journal Article -
8
MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival
Published in The Journal of cell biology (03-03-2014)“…MarvelD3 is a transmembrane component of tight junctions, but there is little evidence for a direct involvement in the junctional permeability barrier. Tight…”
Get full text
Journal Article -
9
Mammalian tight junctions in the regulation of epithelial differentiation and proliferation
Published in Current opinion in cell biology (01-10-2005)“…Tight junctions are important for the permeability properties of epithelial and endothelial barriers as they restrict diffusion along the paracellular space…”
Get full text
Journal Article -
10
Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex
Published in The Journal of cell biology (20-08-2012)“…Epithelial cell-cell adhesion and morphogenesis require dynamic control of actin-driven membrane remodeling. The Rho guanosine triphosphatase (GTPase) Cdc42…”
Get full text
Journal Article -
11
Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function
Published in Scientific reports (15-07-2021)“…Tight junction complexes are involved in the establishment and maintenance of cell polarity and the regulation of signalling pathways, controlling biological…”
Get full text
Journal Article -
12
ZO-1 Guides Tight Junction Assembly and Epithelial Morphogenesis via Cytoskeletal Tension-Dependent and -Independent Functions
Published in Cells (Basel, Switzerland) (25-11-2022)“…Formation and maintenance of tissue barriers require the coordination of cell mechanics and cell-cell junction assembly. Here, we combined methods to modulate…”
Get full text
Journal Article -
13
Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation
Published in The Journal of cell biology (06-01-2014)“…Epithelial cells develop morphologically characteristic apical domains that are bordered by tight junctions, the apical-lateral border. Cdc42 and its effector…”
Get full text
Journal Article -
14
The ZO-1-Associated Y-Box Factor ZONAB Regulates Epithelial Cell Proliferation and Cell Density
Published in The Journal of cell biology (03-02-2003)“…Epithelial tight junctions regulate paracellular permeability, restrict apical/basolateral intramembrane diffusion of lipids, and have been proposed to…”
Get full text
Journal Article -
15
ZO-1 Regulates Hippo-Independent YAP Activity and Cell Proliferation via a GEF-H1- and TBK1-Regulated Signalling Network
Published in Cells (Basel, Switzerland) (01-04-2024)“…Tight junctions are a barrier-forming cell-cell adhesion complex and have been proposed to regulate cell proliferation. However, the underlying mechanisms are…”
Get full text
Journal Article -
16
Regulation of PCNA and Cyclin D1 Expression and Epithelial Morphogenesis by the ZO-1-Regulated Transcription Factor ZONAB/DbpA
Published in Molecular and Cellular Biology (01-03-2006)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
17
The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice
Published in PloS one (30-12-2010)“…Cell-cell adhesion regulates the development and function of epithelia by providing mechanical support and by guiding cell proliferation and differentiation…”
Get full text
Journal Article -
18
Control of neural crest induction by MarvelD3-mediated attenuation of JNK signalling
Published in Scientific reports (19-01-2018)“…Tight junctions are required for the formation of tissue barriers and function as suppressors of signalling mechanisms that control gene expression and cell…”
Get full text
Journal Article -
19
ZONAB Promotes Proliferation and Represses Differentiation of Proximal Tubule Epithelial Cells
Published in Journal of the American Society of Nephrology (01-03-2010)“…Epithelial polarization modulates gene expression. The transcription factor zonula occludens 1 (ZO-1)-associated nucleic acid binding protein (ZONAB) can…”
Get full text
Journal Article -
20
Tight junctions as regulators of tissue remodelling
Published in Current opinion in cell biology (01-10-2016)“…Formation of tissue barriers by epithelial and endothelial cells requires neighbouring cells to interact via intercellular junctions, which includes tight…”
Get full text
Journal Article