Search Results - "Balcarkova, Jana"

Whole-genome optical mapping of bone-marrow myeloma cells reveals association of extramedullary multiple myeloma with chromosome 1 abnormalities by Kriegova, Eva, Fillerova, Regina, Minarik, Jiri, Savara, Jakub, Manakova, Jirina, Petrackova, Anna, Dihel, Martin, Balcarkova, Jana, Krhovska, Petra, Pika, Tomas, Gajdos, Petr, Behalek, Marek, Vasinek, Michal, Papajik, Tomas

“…Extramedullary disease (EMM) represents a rare, aggressive and mostly resistant phenotype of multiple myeloma (MM). EMM is frequently associated with high-risk…”
Get full text

Gain of chromosome 2p in chronic lymphocytic leukemia: significant heterogeneity and a new recurrent dicentric rearrangement by Jarosova, Marie, Urbankova, Helena, Plachy, Radek, Papajik, Tomas, Holzerova, Milena, Balcarkova, Jana, Pikalova, Zuzana, Divoky, Vladimir, Indrak, Karel

“…Array-based comparative genomic hybridization (arrayCGH) studies in chronic lymphocytic leukemia (CLL) have revealed novel recurrent chromosomal imbalances,…”
Get full text

Bone metabolism parameters and their relation to cytogenetics in multiple myeloma by Krhovska, Petra, Pika, Tomas, Proskova, Jitka, Balcarkova, Jana, Zapletalova, Jana, Bacovsky, Jaroslav, Minarik, Jiri

“…Objectives Our aim was to correlate serum levels of selected markers of bone metabolism and bone marrow microenvironment to cytogenetic changes in patients…”
Get full text

Diagnostic deep‐targeted next‐generation sequencing assessment of TP53 gene mutations in multiple myeloma from the whole bone marrow by Petrackova, Anna, Minarik, Jiri, Sedlarikova, Lenka, Libigerova, Tereza, Hamplova, Alzbeta, Krhovska, Petra, Balcarkova, Jana, Pika, Tomas, Papajik, Tomas, Kriegova, Eva

Get full text

CD38‐negative relapse in multiple myeloma after daratumumab‐based chemotherapy by Minarik, Jiri, Novak, Martin, Flodr, Patrik, Balcarkova, Jana, Mlynarcikova, Miroslava, Krhovska, Petra, Pika, Tomas, Pikalova, Zuzana, Bacovsky, Jaroslav, Scudla, Vlastimil

“…We present a case report of a patient relapsing after anti‐CD38 treatment (daratumumab). The phenotype of the disease changed during this treatment, and the…”
Get full text

Aberrations of chromosome X in patients with multiple myeloma by Balcarkova, Jana, Flodr, Patrik, Svobodova, Nela, Pika, Tomas, Krhovska, Petra, Papajik, Tomas, Urbankova, Helena, Minarik, Jiri

Get full text

CD 38‐negative relapse in multiple myeloma after daratumumab‐based chemotherapy by Minarik, Jiri, Novak, Martin, Flodr, Patrik, Balcarkova, Jana, Mlynarcikova, Miroslava, Krhovska, Petra, Pika, Tomas, Pikalova, Zuzana, Bacovsky, Jaroslav, Scudla, Vlastimil

“…We present a case report of a patient relapsing after anti‐ CD 38 treatment (daratumumab). The phenotype of the disease changed during this treatment, and the…”
Get full text

Next-generation optical mapping reveals numerous previously unrecognizable structural variants in multiple myeloma by Fillerova, Regina, Minarik, Jiri, Petrackova, Anna, Mikulkova, Zuzana, Balcarkova, Jana, Krhovska, Petra, Pika, Tomas, Bacovsky, Jaroslav, Gajdos, Petr, Behalek, Marek, Proskova, Jana, Papajik, Tomas, Kriegova, Eva

Get full text

Molecular Cytogenetic Analysis of Chromosome 8 Aberrations in Patients With Multiple Myeloma Examined in 2 Different Stages, at Diagnosis and at Progression/Relapse by Mlynarcikova, Miroslava, Balcarkova, Jana, Mickova, Pavla, Scudla, Vlastimil, Pika, Tomas, Bacovsky, Jaroslav, Minarik, Jiri, Janousova, Eva, Jarosova, Marie

“…This retrospective study of 62 patients with multiple myeloma examined at 2 different phases (diagnosis and progression/relapse), revealed chromosome 8…”
Get full text

Complex karyotype and translocation t(4;14) define patients with high-risk newly diagnosed multiple myeloma: results of CMG2002 trial by Nemec, Pavel, Zemanova, Zuzana, Kuglik, Petr, Michalova, Kyra, Tajtlova, Jana, Kaisarova, Petra, Oltova, Alexandra, Filkova, Hana, Holzerova, Milena, Balcarkova, Jana, Jarosova, Marie, Rabasova, Jana, Hruba, Martina, Spicka, Ivan, Gregora, Evzen, Adam, Zdenek, Scudla, Vlastimil, Maisnar, Vladimir, Schutzova, Miroslava, Hajek, Roman

“…Abstract The prognostic impact of chromosomal abnormalities was evaluated by fluorescence in situ hybridization with cytoplasmic immunoglobulin light chain…”
Get full text

Molecular cytogenetic analysis of chromosome 8 aberrations in multiple myeloma (MM) patients examined in two different stages, at diagnosis and at progression/relapse by Mlynarcikova, Miroslava, Balcarkova, Jana, Mickova, Pavla, Scudla, Vlastimil, Pika, Tomas, Bacovsky, Jaroslav, Minarik, Jiri, Janousova, Eva, Jarosova, Marie

“…Abstract Background The genome of multiple myeloma (MM) clonal plasma cells is characterized by genetic changes of prognostic importance. Disease progression…”
Get full text

Array-based karyotyping in chronic lymphocytic leukemia (CLL) detects new unbalanced abnormalities that escape conventional cytogenetics and CLL FISH panel by Urbankova, Helena, Papajik, Tomas, Plachy, Radek, Holzerova, Milena, Balcarkova, Jana, Divoka, Martina, Prochazka, Vit, Pikalova, Zuzana, Indrak, Karel, Jarosova, Marie

“…Chronic lymphocytic leukemia (CLL) is the most common adult leukemia with a very heterogeneous course. Progress in molecular genetic characterization of CLL…”
Get full text

Bcr-Abl-Independent Activation of Src Kinases Associated with Development of Dasatinib Resistance in a CML Patient by Veselovska, Jitka, Solna, Renata, Jarosova, Marie, Faber, Edgar, Urbankova, Helena, Holzerova, Milena, Balcarkova, Jana, Indrak, Karel, Divoky, Vladimir

“…Activation of Src family of kinases (SFK) is associated with chronic myeloid leukemia (CML) disease progression and resistance to imatinib (IM) therapy…”
Get full text

Gain of chromosome arm 1q in patieznts in relapse and progression of multiple myeloma by Balcarkova, Jana, Urbankova, Helena, Scudla, Vlastimil, Holzerova, Milena, Bacovsky, Jaroslav, Indrak, Karel, Jarosova, Marie

“…Abstract Abnormalities of chromosome 1 are among the most frequent chromosomal aberrations in patients with multiple myeloma (MM) and are considered a…”
Get full text

Gain of chromosome arm 1q in patients in relapse and progression of multiple myeloma by Balcárková, Jana, Urbánková, Helena, Scudla, Vlastimil, Holzerová, Milena, Bacovský, Jaroslav, Indrák, Karel, Jarosová, Marie

“…Abnormalities of chromosome 1 are among the most frequent chromosomal aberrations in patients with multiple myeloma (MM) and are considered a poor-risk genetic…”
Get full text

Analysis of serum free light chains κ/λ ratio and heavy/light chain pairs of immunoglobulin to the stratification of multiple myeloma according to Mayo Stratification of Myeloma and Revised International Staging System by Ščudla, Vlastimil, Balcárková, Jana, Lochman, Pavel, Vincová, Miroslava, Pika, Tomáš, Minařík, Jiří, Zapletalová, Jana, Jarošová, Marie

“…Assessment of serum levels of free light chains (FLC-κ and FLC-λ) and recently heavy/light chain pairs of immunoglobulin (HLC-κ and HLC-λ) and their ratio…”
Get more information

Array comparative genomic hybridization in the detection of chromosomal abnormalities in T-cell prolymphocytic leukemia by Urbánková, Helena, Holzerová, Milena, Balcárková, Jana, Raida, Ludĕk, Procházka, Vít, Pikalová, Zuzana, Papajík, Tomáš, Indrák, Karel, Jarošová, Marie

Get full text

Imatinib mesylate efficacy in 72 previously treated Philadelphia-positive chronic myeloid leukemia patients with and without additional chromosomal changes: single-center results by Holzerová, Milena, Faber, Edgar, Veselovská, Jitka, Urbánková, Helena, Balcárková, Jana, Rožmanová, Šárka, Voglová, Jaroslava, Mužík, Jan, Chroust, Karel, Indrák, Karel, Jarošová, Marie

“…Abstract Reported here are 72 previously treated Philadelphia chromosome–positive (Ph+) CML patients on imatinib (IM) therapy, with a focus on patients with…”
Get full text

CD38-negative relapse in multiple myeloma after daratumumab-based chemotherapy by Minarik, Jiri, Novak, Martin, Flodr, Patrik, Balcarkova, Jana, Mlynarcikova, Miroslava, Krhovska, Petra, Pika, Tomas, Pikalova, Zuzana, Bacovsky, Jaroslav, Scudla, Vlastimil

“…We present a case report of a patient relapsing after anti-CD38 treatment (daratumumab). The phenotype of the disease changed during this treatment, and the…”
Get full text

Original article: Imatinib mesylate efficacy in 72 previously treated Philadelphia-positive chronic myeloid leukemia patients with and without additional chromosomal changes: single-center results by Holzerova, Milena, Faber, Edgar, Veselovska, Jitka, Urbankova, Helena, Balcarkova, Jana, Rozmanova, Sarka, Voglova, Jaroslava, Muzik, Jan, Chroust, Karel, Indrak, Karel, Jarosova, Marie

“…Reported here are 72 previously treated Philadelphia chromosome-positive (Ph+) CML patients on imatinib (IM) therapy, with a focus on patients with additional…”
Get full text